Hafnium oxide

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Hafnium oxide
DrugBank Accession Number
DB17508
Background

Not Available

Type
Small Molecule
Groups
Investigational
Structure
Weight
Average: 210.49
Monoisotopic: 211.93639
Chemical Formula
HfO2
Synonyms
  • Hafnium oxide-containing nanoparticles nbtxr3
External IDs
  • NBTXR3
  • NSC-158931
  • PEP-503
  • PEP503

Pharmacology

Indication

Not Available

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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
3C4Z4KG52T
CAS number
12055-23-1
InChI Key
WIHZLLGSGQNAGK-UHFFFAOYSA-N
InChI
InChI=1S/Hf.2O/q+4;2*-2
IUPAC Name
hafnium(4+) dioxidandiide
SMILES
[O--].[O--].[Hf+4]

References

General References
Not Available
ChemSpider
140196
Wikipedia
Hafnium(IV)_oxide

Clinical Trials

Clinical Trials
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PhaseStatusPurposeConditionsCountStart DateWhy Stopped100+ additional columns
3RecruitingTreatmentAgeing / Locally advanced Squamous cell carcinoma of head and neck1somestatusstop reasonjust information to hide
2RecruitingTreatmentMetastatic Squamous Cell Carcinoma of the Head and Neck (HNSCC) / Recurrent Squamous Cell Carcinoma of the Head and Neck (SCCHN)1somestatusstop reasonjust information to hide
1RecruitingTreatmentImmunotherapy / Metastasis From Malignant Melanoma of Skin (Disorder) / Metastasis From Malignant Tumor of Bladder (Disorder) / Metastasis From Malignant Tumor of Cervix / Metastasis From Malignant Tumor of Liver / Metastatic Non-Small Cell Lung Cancer / Metastatic Renal Cell Carcinoma ( mRCC) / Metastatic Triple Negative Breast Cancers / Microsatellite Instability-High Solid Malignant Tumour / Radiation Therapy / Squamous Cell Carcinoma of the Head and Neck (SCCHN)1somestatusstop reasonjust information to hide
1, 2TerminatedTreatmentProstate Cancer1somestatusstop reasonjust information to hide
1, 2TerminatedTreatmentRectal Cancer1somestatusstop reasonjust information to hide

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
logP-0.65Chemaxon
pKa (Strongest Acidic)15.7Chemaxon
pKa (Strongest Basic)-1.8Chemaxon
Physiological Charge0Chemaxon
Hydrogen Acceptor Count1Chemaxon
Hydrogen Donor Count0Chemaxon
Polar Surface Area0 Å2Chemaxon
Rotatable Bond Count0Chemaxon
Refractivity13.11 m3·mol-1Chemaxon
Polarizability0.95 Å3Chemaxon
Number of Rings0Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterNoChemaxon
Veber's RuleYesChemaxon
MDDR-like RuleNoChemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available
Chromatographic Properties
Collision Cross Sections (CCS)
Not Available

Drug created at February 09, 2023 22:48 / Updated at February 10, 2023 08:56