Orotic acid

DB02262InvestigationalSmall molecule

Orotic acid is a drug used to manage uncomplicated liver dysfunction in combination with xanthine.

Chemical structure of Orotic acid
Formula / weight
C5H4N2O4 · 156.0963 g/mol (avg)
Also known as
Uracil-6-carboxylic acid · Vitamin B13

Resolves to

Compound
UNII61H4T033E5CAS65-86-1ChEMBLCHEMBL1235017ChEBI16742PubChem967KEGGD00055
Clinical / RWD
RxNorm7712
Structure
InChIKeyPXQPEWDEAKTCGB-UHFFFAOYSA-NSMILESOC(=O)C1=CC(=O)NC(=O)N1
Targets
Q08210Dihydroorotate dehydrogenase (quinone), mitochondrialP08870pyrEQ02127DHODHP0A7E1pyrDP05020pyrCQ53ZE5pyrDA

What you can answer from here — as of September 16, 2026

6Protein targetsEach mapped to UniProt, with action and pharmacological action
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2Clinical trialsPhase, status and sponsor resolved per trial
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2Structured indicationsCondition, population, route and combination as fields, not prose
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2ContraindicationsEach with its own population and attribute set
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8Marketed productsAcross 2 countries and 6 labellers
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9+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Orotic acid, and which of those have an active Phase 3 trial?

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