Muscle Spasms

Also known as: Muscle_spasm / Muscle Spasm / Spasms [D] / Muscular spasm / Spasm of muscle / Spasms / Spasm muscle / Spasm

DrugDrug NameDrug Description
DB00316AcetaminophenAn analgesic drug used alone or in combination with opioids for pain management, and as an antipyretic agent.
DB00945Acetylsalicylic acidA salicylate used to treat pain, fever, inflammation, migraines, and reducing the risk of major adverse cardiovascular events.
DB09300ButylscopolamineAn antispasmodic and anticholinergic agent used for the symptomatic treatment of abdominal cramping and pain.
DB00856ChlorphenesinA phenol ether used to treat painful muscular conditions.
DB00924CyclobenzaprineA skeletal muscle relaxant that works on the brainstem to treat muscle spasms of local origin.
DB06751DrotaverineA phosphodiesterase-4 inhibitor used to alleviate gastrointestinal and genitourinary smooth muscle spasms.
DB00749EtodolacAn NSAID used to treat osteoarthritis and rheumatoid arthritis, as well as acute pain.
DB00927FamotidineA histamine H2 receptor antagonist used to treat duodenal ulcers, benign gastric ulcers, GERD, and Zollinger-Ellison syndrome.
DB13414FenyramidolA muscle relaxant indicated in the symptomatic treatment of musculoskeletal pain and spasms.
DB00712FlurbiprofenAn NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis.
DB01050IbuprofenAn NSAID and non-selective COX inhibitor used to treat mild-moderate pain, fever, and inflammation.
DB00186LorazepamA short-acting benzodiazepine commonly used to treat panic disorders, severe anxiety, and seizures.
DB13754MephenoxaloneA muscle relaxant indicated in the treatment of painful muscle spasms and cramps.
DB00423MethocarbamolA CNS depressant indicated with rest, physical therapy and other treatments to control the discomfort associated with various acute musculoskeletal conditions.
DB00788NaproxenAn NSAID used to treat rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, polyarticular juvenile idiopathic arthritis, tendinitis, bursitis, acute gout, primary dysmenorrhea, and mild to moderate pain.
DB01173OrphenadrineA muscarinic antagonist used as an adjunct for the symptomatic relief of musculoskeletal pain and discomfort.
DB14016Ox bile extractNot Annotated
DB13354PhenprobamateA skeletal muscle relaxant indicated in the treatment of pain caused by muscle spasms.
DB11582ThiocolchicosideA semi-synthetic colchicine derivative used as an analgesic and anti-inflammatory.
DrugDrug NameTargetType
DB00316AcetaminophenProstaglandin G/H synthase 1target
DB00316AcetaminophenProstaglandin G/H synthase 2target
DB00316AcetaminophenCytochrome P450 1A2enzyme
DB00316AcetaminophenCytochrome P450 2E1enzyme
DB00316AcetaminophenP-glycoprotein 1transporter
DB00316AcetaminophenCytochrome P450 2D6enzyme
DB00316AcetaminophenCytochrome P450 2A6enzyme
DB00316AcetaminophenCytochrome P450 3A4enzyme
DB00316AcetaminophenUDP-glucuronosyltransferase 1-1enzyme
DB00316AcetaminophenUDP-glucuronosyltransferase 1-6enzyme
DB00316AcetaminophenUDP-glucuronosyltransferase 1-9enzyme
DB00316AcetaminophenUDP-glucuronosyltransferase 2B15enzyme
DB00316AcetaminophenSulfotransferase 1A1enzyme
DB00316AcetaminophenSulfotransferase 1A3/1A4enzyme
DB00316AcetaminophenArylamine N-acetyltransferase 2enzyme
DB00316AcetaminophenProstaglandin E synthase 3target
DB00316AcetaminophenTransient receptor potential cation channel subfamily V member 1target
DB00316AcetaminophenSerum albumincarrier
DB00316AcetaminophenFatty-acid amide hydrolase 1enzyme
DB00316AcetaminophenGlutathione S-transferase Penzyme
DB00316AcetaminophenGlutathione S-transferase Mu 1enzyme
DB00945Acetylsalicylic acidProstaglandin G/H synthase 1target
DB00945Acetylsalicylic acidProstaglandin G/H synthase 2target
DB00945Acetylsalicylic acidAldo-keto reductase family 1 member C1target
DB00945Acetylsalicylic acidSolute carrier family 22 member 6transporter
DB00945Acetylsalicylic acidP-glycoprotein 1transporter
DB00945Acetylsalicylic acidCytochrome P450 2C19enzyme
DB00945Acetylsalicylic acidCytochrome P450 2C9enzyme
DB00945Acetylsalicylic acid5'-AMP-activated protein kinasetarget
DB00945Acetylsalicylic acidEndothelin-1 receptortarget
DB00945Acetylsalicylic acidCellular tumor antigen p53target
DB00945Acetylsalicylic acid78 kDa glucose-regulated proteintarget
DB00945Acetylsalicylic acidRibosomal protein S6 kinase alpha-3target
DB00945Acetylsalicylic acidNF-kappa-B inhibitor alphatarget
DB00945Acetylsalicylic acidTumor necrosis factor-inducible gene 6 proteintarget
DB00945Acetylsalicylic acidCaspase-1target
DB00945Acetylsalicylic acidCaspase-3target
DB00945Acetylsalicylic acidInhibitor of nuclear factor kappa-B kinase subunit betatarget
DB00945Acetylsalicylic acidExtracellular signal-regulated kinase (ERK)target
DB00945Acetylsalicylic acidG1/S-specific cyclin-D1target
DB00945Acetylsalicylic acidMyc proto-oncogene proteintarget
DB00945Acetylsalicylic acidProliferating cell nuclear antigentarget
DB00945Acetylsalicylic acidCyclin Atarget
DB00945Acetylsalicylic acidUDP-glucuronosyltransferase 1-6enzyme
DB00945Acetylsalicylic acidArylamine N-acetyltransferase 2enzyme
DB00945Acetylsalicylic acidSolute carrier family 22 member 8transporter
DB00945Acetylsalicylic acidSialidase-1target
DB09300ButylscopolamineMuscarinic acetylcholine receptor M3target
DB09300ButylscopolamineMuscarinic acetylcholine receptor M2target
DB00856ChlorphenesinCytochrome P450 19A1enzyme
DB00856ChlorphenesinCytochrome P450 3A4enzyme
DB00856ChlorphenesinXanthine dehydrogenase/oxidaseenzyme
DB00856ChlorphenesinProstaglandin G/H synthase 2enzyme
DB00856ChlorphenesinCholinesteraseenzyme
DB00924Cyclobenzaprine5-hydroxytryptamine receptor 2Atarget
DB00924CyclobenzaprineCytochrome P450 1A2enzyme
DB00924CyclobenzaprineCytochrome P450 3A4enzyme
DB00924CyclobenzaprineCytochrome P450 2D6enzyme
DB00924CyclobenzaprineSerum albumincarrier
DB00924CyclobenzaprineUDP-glucuronosyltransferase 1-4enzyme
DB00924CyclobenzaprineUDP-glucuronosyltransferase 2B10enzyme
DB00924Cyclobenzaprine5-hydroxytryptamine receptor 2Btarget
DB00924Cyclobenzaprine5-hydroxytryptamine receptor 2Ctarget
DB00924Cyclobenzaprine5-hydroxytryptamine receptor 7target
DB00924Cyclobenzaprine5-hydroxytryptamine receptor 6target
DB00924CyclobenzaprineSodium-dependent serotonin transportertarget
DB00924CyclobenzaprineSodium-dependent noradrenaline transportertarget
DB00924CyclobenzaprineToll-like receptor 4target
DB00924CyclobenzaprineAldehyde oxidasetarget
DB06751DrotaverinecAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
DB06751DrotaverineVoltage-dependent L-type calcium channeltarget
DB00749EtodolacProstaglandin G/H synthase 1target
DB00749EtodolacProstaglandin G/H synthase 2target
DB00749EtodolacCytochrome P450 2C9enzyme
DB00749EtodolacUDP-glucuronosyltransferase 1-9enzyme
DB00749EtodolacRetinoic acid receptor RXR-alphatarget
DB00749EtodolacSerum albumincarrier
DB00749EtodolacSolute carrier family 22 member 6transporter
DB00749EtodolacUDP-glucuronosyltransferase 1-3enzyme
DB00749EtodolacUDP-glucuronosyltransferase 1-10enzyme
DB00749EtodolacUDP-glucuronosyltransferase 2B7enzyme
DB00927FamotidineHistamine H2 receptortarget
DB00927FamotidineSolute carrier family 22 member 2transporter
DB00927FamotidineSolute carrier family 22 member 8transporter
DB00927FamotidineMultidrug and toxin extrusion protein 1transporter
DB00927FamotidineCytochrome P450 1A2enzyme
DB00927FamotidineSolute carrier family 22 member 6transporter
DB00712FlurbiprofenProstaglandin G/H synthase 2target
DB00712FlurbiprofenProstaglandin G/H synthase 1target
DB00712FlurbiprofenCytochrome P450 2C9enzyme
DB00712FlurbiprofenSerum albumincarrier
DB00712FlurbiprofenMultidrug resistance-associated protein 4transporter
DB00712FlurbiprofenSolute carrier family 22 member 6transporter
DB00712FlurbiprofenUDP-glucuronosyltransferase 2B7enzyme
DB00712FlurbiprofenUDP-glucuronosyltransferase 1-1enzyme
DB00712FlurbiprofenUDP-glucuronosyltransferase 1-3enzyme
DB00712FlurbiprofenUDP-glucuronosyltransferase 1-9enzyme
DB00712FlurbiprofenUDP-glucuronosyltransferase 2B4enzyme
DB01050IbuprofenProstaglandin G/H synthase 1target
DB01050IbuprofenProstaglandin G/H synthase 2target
DB01050IbuprofenCytochrome P450 2C9enzyme
DB01050IbuprofenSerum albumincarrier
DB01050IbuprofenMultidrug resistance-associated protein 4transporter
DB01050IbuprofenMultidrug resistance-associated protein 1transporter
DB01050IbuprofenSolute carrier organic anion transporter family member 1A2transporter
DB01050IbuprofenSolute carrier family 22 member 6transporter
DB01050IbuprofenSolute carrier family 22 member 8transporter
DB01050IbuprofenSolute carrier family 22 member 11transporter
DB01050IbuprofenSolute carrier organic anion transporter family member 2B1transporter
DB01050IbuprofenP-glycoprotein 1transporter
DB01050IbuprofenUDP-glucuronosyltransferase 1-3enzyme
DB01050IbuprofenUDP-glucuronosyltransferase 1-9enzyme
DB01050IbuprofenUDP-glucuronosyltransferase 2B4enzyme
DB01050IbuprofenUDP-glucuronosyltransferase 2B7enzyme
DB01050IbuprofenCytochrome P450 2C8enzyme
DB01050IbuprofenCytochrome P450 2C19enzyme
DB01050IbuprofenApoptosis regulator Bcl-2target
DB01050IbuprofenThrombomodulintarget
DB01050IbuprofenFatty acid-binding protein, intestinaltarget
DB01050IbuprofenPeroxisome proliferator-activated receptor gammatarget
DB01050IbuprofenCystic fibrosis transmembrane conductance regulatortarget
DB01050IbuprofenPeroxisome proliferator-activated receptor alphatarget
DB01050IbuprofenPlatelet glycoprotein Ib alpha chaintarget
DB01050IbuprofenProtein S100-A7target
DB01050IbuprofenAlpha-methylacyl-CoA racemaseenzyme
DB01050IbuprofenCytochrome P450 3A4enzyme
DB00186LorazepamUDP-glucuronosyltransferase 2B15enzyme
DB00186LorazepamGABA(A) Receptortarget
DB00186LorazepamCytochrome P450 3A4enzyme
DB00186LorazepamGABA(A) Receptor Benzodiazepine Binding Sitetarget
DB00423MethocarbamolCarbonic anhydrase 1target
DB00788NaproxenProstaglandin G/H synthase 1target
DB00788NaproxenProstaglandin G/H synthase 2target
DB00788NaproxenSerum albumincarrier
DB00788NaproxenCytochrome P450 2C9enzyme
DB00788NaproxenCytochrome P450 1A2enzyme
DB00788NaproxenSolute carrier organic anion transporter family member 1A2transporter
DB00788NaproxenSolute carrier family 22 member 6transporter
DB00788NaproxenCytochrome P450 2C8enzyme
DB00788NaproxenUDP-glucuronosyltransferase 2B7enzyme
DB00788NaproxenPeptostreptococcal albumin-binding proteintarget
DB00788NaproxenBile salt export pumptransporter
DB00788NaproxenP-glycoprotein 1transporter
DB00788NaproxenUDP-glucuronosyltransferase 1-3enzyme
DB00788NaproxenUDP-glucuronosyltransferase 1-6enzyme
DB00788NaproxenUDP-glucuronosyltransferase 1-7enzyme
DB00788NaproxenUDP-glucuronosyltransferase 1-8enzyme
DB00788NaproxenUDP-glucuronosyltransferase 1-9enzyme
DB00788NaproxenUDP-glucuronosyltransferase 1-10enzyme
DB00788NaproxenSolute carrier family 22 member 8transporter
DB01173OrphenadrineGlutamate receptor ionotropic, NMDA 1target
DB01173OrphenadrineGlutamate receptor ionotropic, NMDA 2Dtarget
DB01173OrphenadrineGlutamate receptor ionotropic, NMDA 3Btarget
DB01173OrphenadrineGlutamate receptor ionotropic, NMDA 3Atarget
DB01173OrphenadrineHistamine H1 receptortarget
DB01173OrphenadrineCytochrome P450 2B6enzyme
DB01173OrphenadrineCytochrome P450 2E1enzyme
DB01173OrphenadrineCytochrome P450 3A4enzyme
DB01173OrphenadrineSodium-dependent noradrenaline transportertarget
DB01173OrphenadrineSodium channel protein type 10 subunit alphatarget
DB01173OrphenadrineCytochrome P450 1A2enzyme
DB01173OrphenadrineCytochrome P450 2D6enzyme
DB11582ThiocolchicosideGABA(A) Receptortarget
DB11582ThiocolchicosideGlycine receptor subunit alpha-1target
DB11582ThiocolchicosideTumor necrosis factor ligand superfamily member 11target
DrugDrug NamePhaseStatusCount
DB06264Tolperisone2Completed1
DB06264Tolperisone3Recruiting1
DB00181BaclofenNot AvailableCompleted1
DB00297BupivacaineNot AvailableCompleted1
DB06774CapsaicinNot AvailableCompleted1
DB00924CyclobenzaprineNot AvailableCompleted1
DB00586DiclofenacNot AvailableCompleted1
DB00712FlurbiprofenNot AvailableCompleted1
DB00996GabapentinNot AvailableCompleted1
DB01221KetamineNot AvailableCompleted1
DB00825LevomentholNot AvailableCompleted1
DB00281LidocaineNot AvailableCompleted1
DB00814MeloxicamNot AvailableCompleted1
DB00750PrilocaineNot AvailableCompleted1
DB00669SumatriptanNot AvailableCompleted1
DB00697TizanidineNot AvailableCompleted1
DB00273TopiramateNot AvailableCompleted1