Reaction: Methadone to 2 products

cyclisationMajor circulating metaboliteSpontaneousMetabolism of Methadone

Methadone is converted to 2-Ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine and [S-(E)]-2-Ethylidene-1,5-dimethyl-3,3-diphenyl-pyrrolidine spontaneously.

Direction
Activity
inactive

What you can answer from here — as of September 10, 2019

6EnzymesEach linked to its target card
Listed above
3ReferencesThe literature this reaction is curated from
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Which other drugs are metabolised by Cytochrome P450 2D6, Cytochrome P450 3A4, and Cytochrome P450 2B6, and which of those pairings are clinically significant?

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