Reaction: Oxcarbazepine to 1 product

Reaction
Reaction type
reduction
Direction
Major circulating metabolite?
Yes
Spontaneous?
No
Activity
active
References
  1. Malatkova P, Havlikova L, Wsol V: The role of carbonyl reducing enzymes in oxcarbazepine in vitro metabolism in man. Chem Biol Interact. 2014 Sep 5;220:241-7. doi: 10.1016/j.cbi.2014.07.005. Epub 2014 Jul 22. [Article]
  2. Schutz H, Feldmann KF, Faigle JW, Kriemler HP, Winkler T: The metabolism of 14C-oxcarbazepine in man. Xenobiotica. 1986 Aug;16(8):769-78. doi: 10.3109/00498258609043567. [Article]
Comments
Not Available
Enzymes
EnzymeKmVmaxRole
Aldo-keto reductase family 1 member C1Not AvailableNot Availableconfirmed
Aldo-keto reductase family 1 member C2Not AvailableNot Availableconfirmed
Aldo-keto reductase family 1 member C3Not AvailableNot Availableconfirmed
Aldo-keto reductase family 1 member C4Not AvailableNot Availableconfirmed
Carbonyl reductase [NADPH] 1Not AvailableNot Availableconfirmed
Carbonyl reductase [NADPH] 3Not AvailableNot Availableconfirmed