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Displaying results 91 - 100 of 1841 in total
  1. Drug

    Diazoxide

    go.drugbank.com/drugs/DB01119
    ApprovedInvestigational

    Diazoxide is a non-diuretic benzothiadiazine derivative that activates ATP-sensitive potassium channels.

    Categories: Potassium Channel Opener
  2. Pathway

    Furosemide Diuretic Action Pathway

    smpdb.ca/view/SMP0122712
    Drug action

    Furosemide may also inhibit sodium and chloride reabsorption in the proximal and distal tubules.

    Drugs: Furosemide · Potassium cation
    Enzymes: Chloride channel protein ClC-Ka, Sodium/potassium-transporting ATPase subunit alpha-1
  3. Indication

    Hypotonic Dehydration

    go.drugbank.com/conditions/DBCOND0135077
    Drugs: Potassium chloride · Sodium chloride
  4. Pathway

    Torasemide Action Pathway (New)

    smpdb.ca/view/SMP0124537
    Drug action

    Torasemide is a loop diuretic drug, administered orally or intravenously to treat hypertension and edema associated with heart failure, renal failure, or liver disease. It targets the nephrons of the kidney, mainly the ascending limb of ...

    Drugs: Torasemide · Potassium cation
    Enzymes: Chloride channel protein ClC-Ka, Sodium/potassium-transporting ATPase subunit alpha-1
  5. Pathway

    Hydrochlorothiazide Diuretic Action Pathway

    smpdb.ca/view/SMP0122688
    Drug action

    In the distal convoluted tubule (DCT), the regulation of ions such as sodium, potassium, calcium, chloride, and magnesium occurs. … transporter which transports chloride into the interstitium-blood.

    Drugs: Hydrochlorothiazide · Potassium cation · Calcium
    Enzymes: Chloride channel protein ClC-Ka, Sodium/potassium-transporting ATPase subunit alpha-1
  6. Pathway

    Hydroflumethiazide Diuretic Action Pathway

    smpdb.ca/view/SMP0123142
    Drug action

    In the distal convoluted tubule (DCT), the regulation of ions such as sodium, potassium, calcium, chloride and magnesium occur. … transporter which transports chloride into the interstitium-blood.

    Drugs: Hydroflumethiazide · Potassium cation · Calcium
    Enzymes: Chloride channel protein ClC-Ka, Sodium/potassium-transporting ATPase subunit alpha-1
  7. Pathway

    Chlorthalidone Diuretic Action Pathway

    smpdb.ca/view/SMP0123149
    Drug action

    In the distal convoluted tubule (DCT), the regulation of ions such as sodium, potassium, calcium, chloride, and magnesium occurs. … transporter which transports chloride into the interstitium-blood.

    Drugs: Chlorthalidone · Potassium cation · Calcium
    Enzymes: Chloride channel protein ClC-Ka, Sodium/potassium-transporting ATPase subunit alpha-1
  8. Pathway

    Polythiazide Diuretic Action Pathway

    smpdb.ca/view/SMP0123144
    Drug action

    In the distal convoluted tubule (DCT), the regulation of ions such as sodium, potassium, calcium, chloride, and magnesium occurs. … transporter which transports chloride into the interstitium-blood.

    Drugs: Polythiazide · Potassium cation · Calcium
    Enzymes: Chloride channel protein ClC-Ka, Sodium/potassium-transporting ATPase subunit alpha-1
  9. Pathway

    Cyclothiazide Diuretic Action Pathway

    smpdb.ca/view/SMP0123145
    Drug action

    In the distal convoluted tubule (DCT), the regulation of ions such as sodium, potassium, calcium, chloride and magnesium occur. … transporter which transports chloride into the interstitium-blood.

    Drugs: Cyclothiazide · Potassium cation · Calcium
    Enzymes: Chloride channel protein ClC-Ka, Sodium/potassium-transporting ATPase subunit alpha-1
  10. Pathway

    Benzthiazide Action Pathway

    smpdb.ca/view/SMP0126366
    Drug action

    In consequence, this will increase potassium excretion via the sodium-potassium exchange mechanism. The exact name of the inhibited transporter is the solute carrier family 12 member 3. … This inhibition of the cotransporter results in the increased excretion of sodium, chloride, and, in consequence, water.

    Drugs: Benzthiazide · Potassium cation · Calcium
    Enzymes: Chloride channel protein ClC-Ka, Sodium/potassium-transporting ATPase subunit alpha-1