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Fluspirilene Mechanism of Action Action Pathway
smpdb.ca/view/SMP0126514Drug actionFluspirilene is an antipsychotic agent used in the treatment of schizophrenia. Fluspirilene is a relatively long-acting injectable depot antipsychotic drug used for schizophrenia. Fluspirilene does not differ greatly from other depot ant...
Flupentixol Dopamine Antagonist Action Pathway
smpdb.ca/view/SMP0126515Drug actionFlupentixol is a first generation antipsychotic drug of the thioxanthene group. It exists in two geometric isomers, the trans(E) and pharmacologically active cis(Z) forms. Flupentixol decanoate is one of the active ingredients found in i...
Pimozide Mechanism of Action Action Pathway
smpdb.ca/view/SMP0126532Drug actionPimozide is a member of the class of benzimidazoles that is 1,3-dihydro-2H-benzimidazol-2-one in which one of the nitrogens is substituted by a piperidin-4-yl group, which in turn is substituted on the nitrogen by a 4,4-bis(p-fluoropheny...
Thioridazine Dopamine Antagonist Action Pathway
smpdb.ca/view/SMP0126559Drug actionThioridazine is a trifluoro-methyl phenothiazine derivative. Thioridazine blocks postsynaptic mesolimbic dopaminergic D1 and D2 receptors in the brain; blocks alpha-adrenergic effect, depresses the release of hypothalamic and hypophyseal...
Trifluoperazine Dopamine Antagonist Action Pathway
smpdb.ca/view/SMP0126561Drug actionTrifluoperazine is a trifluoro-methyl phenothiazine derivative. Trifluoperazine blocks postsynaptic mesolimbic dopaminergic D1 and D2 receptors in the brain; depresses the release of hypothalamic and hypophyseal hormones and is believed ...
Methotrimeprazine Dopamine Antagonist Action Pathway
smpdb.ca/view/SMP0126562Drug actionMethotrimeprazine is a phenothiazine derivative, a first-generation antipsychotic, dopamine receptor antagonists (DRA) and a typical antipsychotic. Methotrimeprazine's antipsychotic effect is largely due to its antagonism of dopamine rec...
Acepromazine Dopamine Antagonist Action Pathway
smpdb.ca/view/SMP0126576Drug actionAcepromazine is a phenothiazine tranquilizer that blocks dopamine receptors in the CNS and depresses the reticular-activating system, resulting in sedation. Acepromazine was first used in humans in the 1950s as an antipsychotic agent. It...
Thiothixene Dopamine Antagonist Action Pathway
smpdb.ca/view/SMP0126580Drug actionThiothixene is an antipsychotic of the thioxanthene series. Thiothixene acts as an antagonist (blocking agent) on different post-sysnaptic receptors -on dopaminergic-receptors (subtypes D1, D2, D3 and D4 - different antipsychotic propert...
Haloperidol Dopamine Antagonist Action Pathway
smpdb.ca/view/SMP0126593Drug actionHaloperidol is a high potency first-generation (typical) antipsychotic. is indicated for the treatment of the manifestations of several psychotic disorders including schizophrenia, acute psychosis, Tourette syndrome, and other severe beh...
Prochlorperazine - Dopamine Antagonist Action Pathway
smpdb.ca/view/SMP0126629Drug actionProchlorperazine is administered orally. It is a phenothiazine derivative, used in the treatment of schizophrenia and anxiety and to relieve severe nausea and vomiting. Dopamine-antagonizing medications such as prochlorperazine are thoug...
Drugs: Pyridoxal phosphate · Tyrosine · Sapropterin · Prochlorperazine · Dopamine · Levodopa +2 more