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Displaying results 91 - 100 of 10000 in total
  1. Drug

    Sennosides

    go.drugbank.com/drugs/DB11365
    ApprovedInvestigational

    Sennoside A, one of the sennosides present in the laxative medication, has recently proven effective in inhibiting the ribonuclease H (RNase H) activity of human immunodeficiency virus (HIV) reverse transcriptase … It typically begins working in minutes when given by rectum and within twelve hours when given by mouth[FDA Label]. It is a weaker laxative than bisacodyl or castor oil[A177092].

    Salts: Sennosides A and BMixtures: BEKUNIS 3 MG/5 MG KAPLI TABLET, 30 ADET, 2 In 1laxative Stool Softener and Stiulant Laxative
  2. Drug

    Dapsone

    go.drugbank.com/drugs/DB00250
    ApprovedInvestigational

    It is also used with pyrimethamine in the treatment of malaria. (From Martindale, The Extra Pharmacopoeia, 30th ed, p157-8) … A sulfone active against a wide range of bacteria but mainly employed for its actions against mycobacterium leprae.

    Synonyms: 4-(4-aminophenylsulfonyl)aniline, p,p-sulphonylbisbenzamineMixtures: Dapsone 6% / Niacinamide 2% / Spironolactone 5%, Dapsone 8.5% / Niacinamide 2% / Spironolactone 5%
  3. Drug

    Ambroxol

    go.drugbank.com/drugs/DB06742
    ApprovedInvestigational

    Ambroxol is a secretolytic agent used in the treatment of respiratory diseases associated with viscid or excessive mucus. It is the active ingredient of Mucosolvan, Lasolvan or Mucoangin. … The substance is a mucoactive drug with several properties including secretolytic and secretomotoric actions that restore the physiological clearance mechanisms of the respiratory tract which play an important

    Mixtures: AMBROXOL 15 MG+ CLENBUTEROL 10 MCG /5 ML, VAKSAN COMPOSITUM JARABE ADULTOS 15 MG/0.01 MG/ 5MLCategories: Selective Beta 2-adrenergic Agonists, Cytochrome P-450 Substrates
  4. Drug

    Tetracycline

    go.drugbank.com/drugs/DB00759
    ApprovedInvestigationalVet approvedWithdrawn

    The FDA withdrew its approval for the use of all liquid oral drug products formulated for pediatric use containing tetracycline in a concentration greater than 25 mg/ml. … It exerts a bacteriostatic effect on bacteria by binding reversible to the bacterial 30S ribosomal subunit and blocking incoming aminoacyl tRNA from binding to the ribosome acceptor site.

    Synonyms: (4S,4aS,5aS,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamideMixtures: Pylera 140 mg/125 mg/125 mg Hartkapseln, Pylera 140 mg/125 mg/125 mg Hartkapseln
  5. Drug

    Alirocumab

    go.drugbank.com/drugs/DB09302
    ApprovedInvestigational

    Alirocumab is a biopharmaceutical that obtained FDA approval in July 2015 as a second line treatment for high cholesterol in adults whose LDL-cholesterol (LDL-C) is not controlled by the combination of … The FDA approval was contingent on the completion of further clinical trials to better determine efficacy and safety. PCSK9 inhibition facilitates more LDL-C clearance from the blood.

    Categories: Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) InhibitorsProducts: PRALUENT 75 MG/ML (SOLUTION FOR INJECTION IN PRE-FILLED PEN), Praluent 75 mg solution for injection in pre-filled pen
  6. Drug

    Methoxy polyethylene glycol-epoetin beta

    go.drugbank.com/drugs/DB09107
    ApprovedInvestigational

    Methoxy polyethylene glycol-epoetin beta is a chemically synthesised Erythropoiesis Stimulating Agent (ESA) with a longer half-life than erythropoietin.

    Categories: Compounds used in a research, industrial, or household settingProducts: MIRCERA 75 UG/0.3 ML, MIRCERA 75 UG/0.3ML
  7. Target

    Lymphocyte antigen 75

    go.drugbank.com/bio_entities/BE0010744
    TargetHumans

    Acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen-processing compartment (By similarity). Causes reduced proliferation of B-lymphocytes

    Polypeptides: Lymphocyte antigen 75Synonyms: Ly-75
  8. Drug

    Cefaclor

    go.drugbank.com/drugs/DB00833
    ApprovedInvestigational

    Semisynthetic, broad-spectrum antibiotic derivative of cephalexin.

    Mixtures: SEFKLAV 250/62.5 MG EFERVESAN TABLET, 20 ADET, SEFKLAV 500/125 MG EFERVESAN TABLET, 20 ADETCategories: Heterocyclic Compounds, 2-Ring
  9. Drug

    Ciprofloxacin

    go.drugbank.com/drugs/DB00537
    ApprovedInvestigational

    [L6469,L6472,L6475,L6478,L6481,L6484,L6487,L6490,L6493] The first ciprofloxacin containing product was FDA approved on 22 October 1987.[L6463] … Ciprofloxacin is a second generation fluoroquinolone that has spawned many derivative antibiotics.

    Synonyms: 1-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acidMixtures: SIPROGUT PLUS %0.3 + %0.1 KULAK DAMLASI, ÇÖZELTİ, 5 ML, ORCIPOL 500 MG/500 MG FILM TABLET, 28 ADET
  10. Drug

    Iodide I-131

    go.drugbank.com/drugs/DB09293
    ApprovedInvestigational

    For this reason, less toxic iodine isotopes such as I-123 are more frequently used in nuclear imaging, while I-131 is reserved for its tissue destroying effects. … Iodide I-131 (as Sodium iodide I-131) is a radioisotopic drug used for the treatment and palliation of thyroid malignancy.

    Synonyms: 131 I, 131-ISalts: Sodium iodide I-131