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Displaying results 91 - 100 of 10000 in total
  1. Drug

    Sodium chloride

    go.drugbank.com/drugs/DB09153
    ApprovedInvestigationalVet approved

    Sodium chloride, also known as salt, common salt, table salt or halite, is an ionic compound with the chemical formula NaCl, representing a 1:1 ratio of sodium and chloride ions. … Sodium chloride is the primary salt in seawater and in the extracellular fluid of many multicellular organisms. It is listed on the World Health Organization Model List of Essential Medicines.

    Mixtures: GLUCOSA AL 5% EN SOLUCION DE CLORURO DE SODIO AL 0.9%, INYECCION DE DEXTROSA AL 5% CLORURO DE POTASIO (20 MEG) Y CLORURO DE SODIO AL 0.2 %Products: CLORURO DE SODIO AL 0.9%, SOLUCION FISIOLOGICA DE CLORURO DE SODIO AL 0.9%
  2. Drug

    Potassium chloride

    go.drugbank.com/drugs/DB00761
    ApprovedInvestigationalWithdrawn

    A white crystal or crystalline powder used as an electrolyte replenisher, in the treatment of hypokalemia, in buffer solutions, and in fertilizers and explosives. … The FDA withdrew its approval for the use of all solid oral dosage form drug products containing potassium chloride that supply 100 mg or more of potassium per dosage unit, except for controlled-release

    Synonyms: Chloride of potash, Muriate of potashInternational brands: Kaon Cl, Kaon-CL 10
  3. Drug

    Tramadol

    go.drugbank.com/drugs/DB00193
    ApprovedInvestigational

    [A4269,A183842] Tramadol has also been shown to affect a number of other pain modulators within the central nervous system as well as non-neuronal inflammatory markers and immune mediators. … It is considered a Step 2 option on the World Health Organization's pain ladder and has about 1/10th of the potency of [morphine].

    Mixtures: Ag-acet-tramadol, ONEMER DTCategories: Combined Inhibitors of Serotonin/Norepinephrine Reuptake, Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome
  4. Drug

    Hydrochlorothiazide

    go.drugbank.com/drugs/DB00999
    ApprovedInvestigationalVet approved

    [A185138,L8447,L8450] Hydrochlorothiazide use is common but declining in favour of angiotensin converting enzyme inhibitors.

    Mixtures: LOSARTAN-KAL HCTAD100/25, LOSARTAN KAL HCTAD 100/25Categories: combinations of sulfonamides, Medications that reduce magnesium levels
  5. Drug

    KAI-1678

    go.drugbank.com/drugs/DB16211
    Investigational

    KAI-1678 is under investigation in clinical trial NCT01106716 (Safety and Efficacy Study of KAI-1678 to Treat Pain in Subjects With Postherpetic Neuralgia).

  6. Drug

    KAI-1455

    go.drugbank.com/drugs/DB06064
    Experimental

    In preclinical studies, KAI-1455 showed a dramatic reduction in infarct size when delivered prior to the ischemic insult. … KAI-1455 is a selective epsilon protein kinase C (εPKC) activator designed to reduce ischemic organ injury during procedures where blood supply may be compromised, such as coronary artery bypass grafting

  7. Drug

    Theophylline

    go.drugbank.com/drugs/DB00277
    ApprovedInvestigational

    Mechanistically, theophylline acts as a phosphodiesterase inhibitor, adenosine receptor blocker, and histone deacetylase activator. … A methylxanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities.

    Mixtures: TUSBRON-A JARABE, THEOLONG 600/200 MG EFERVESAN TABLET, 10 ADETCategories: combinations of xanthines, Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index
  8. Drug

    Cyclopentolate

    go.drugbank.com/drugs/DB00979
    Approved

    A parasympatholytic anticholinergic used solely to obtain mydriasis or cycloplegia.

    Products: Ak-pentolate, CICLOPENTOLATO AL 1 %
  9. Drug

    Pentoxifylline

    go.drugbank.com/drugs/DB00806
    ApprovedInvestigational

    [A226410, A226415, A226455] More recently, PTX has been suggested as a possible treatment for COVID-19-induced pulmonary complications due to its ability to regulate the production of inflammatory cytokines … Pentoxifylline (PTX) is a synthetic dimethylxanthine derivative that modulates the rheological properties of blood and also has both anti-oxidant and anti-inflammatory properties.

    Categories: Compounds used in a research, industrial, or household setting, combinations of xanthinesInternational brands: An Ruo Ning, Ao Le Ni
  10. Drug

    Ginkgo biloba

    go.drugbank.com/drugs/DB01381
    ApprovedInvestigationalNutraceutical

    [A232379] _Ginkgo folium_, the leaf extract of _Ginkgo biloba_, is considered an anti-dementia drug by the World Health Organization.[A232389] … [L32789] _Ginkgo biloba_ is an herbal plant that is now cultivated worldwide. It is originally native to China, and _ginkgo biloba_ extract has been used in traditional Chinese medicine for centuries.

    Mixtures: Ultra Eye Therapy Drops, DOMINGO 10/10/80 MG EFERVESAN TABLET, 30 ADETCategories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates