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Sennosides
go.drugbank.com/drugs/DB11365ApprovedInvestigationalIt is a weaker laxative than bisacodyl or castor oil[A177092]. … Sennosides (also known as senna glycoside or senna) is a medication used to treat constipation[FDA Label][L771] and empty the large intestine before surgery.
Salts: Sennosides A and BMixtures: Sennosides 8.6 Mg and Docusate Sodium 50 Mg Tablets, Senna Plus Standardized Senna Concentrate 8.6 mg and Docusate Sodium 50 mg EachIomeprol
go.drugbank.com/drugs/DB11705ApprovedInvestigationalIomeprol is a tri-iodinated, non-ionic radiographic contrast agent for intraarterial or intravenous use.
Categories: Compounds used in a research, industrial, or household settingProducts: IOMERON 350 INJECTION 350 mg/ml, IOMERON 150 100 ML FLAKONFlurbiprofen
go.drugbank.com/drugs/DB00712ApprovedInvestigationalFlurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic and analgesic activity.
Mixtures: FULDUO 100 MG/8 MG FİLM KAPLI TABLET, 14 ADET, KLORHEX PLUS 2.5 MG/ML + 1.2 MG/ML ORAL SPREY, ÇÖZELTİ, 30 MLCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesErlotinib
go.drugbank.com/drugs/DB00530ApprovedInvestigationalRecent studies demonstrate that erlotinib is also a potent inhibitor of JAK2V617F, which is a mutant form of tyrosine kinase JAK2 found in most patients with polycythemia vera (PV) and a substantial proportion … Erlotinib binds to the epidermal growth factor receptor (EGFR) tyrosine kinase in a reversible fashion at the adenosine triphosphate (ATP) binding site of the receptor.
Categories: Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2C8 Substrates with a Narrow Therapeutic IndexProducts: TIRLEB® 150 MG, ERLONIB 150 FILM COATED TABLETS 150 mgDesloratadine
go.drugbank.com/drugs/DB00967ApprovedInvestigationalDesloratadine is a second generation, tricyclic antihistamine that which has a selective and peripheral H1-antagonist action. … It is the active descarboethoxy metabolite of loratidine (a second generation histamine).
Mixtures: DELOFED MR 2.5/120 MG KAPSUL, 10 ADET, DELODAY PLUS 120 MG/2,5 MG EFERVESAN TABLET, 10 ADETProducts: URTISIN LAM, TENEDES 0.5 MG/ML ŞURUP,150 MLAtropine
go.drugbank.com/drugs/DB00572ApprovedInvestigationalVet approvedIt is a racemic mixture of d-and l-hyoscyamine, of which only l-hyoscyamine is pharmacologically active. … [A251660] Atropine is a relatively inexpensive drug and is included in the World Health Organization List of Essential Medicines.[A251675]
Mixtures: LOMOTİL 2,5 MG + 0,025 MG / 5 ML ORAL ÇÖZELTİ, 60 ML, PHARMANIAGA DIPHENOXYLATE A TABLETProducts: N/a, ATROSOL EYE DROPS 10 mg/mlDyphylline
go.drugbank.com/drugs/DB00651ApprovedWithdrawnDyphylline is a theophylline derivative with broncho- and vasodilator properties. It is typically used in the management of asthma, cardiac dyspnea, and bronchitis.
Mixtures: ESPEKTAN A ŞURUP, 100 ML, ESPEKTAN ŞURUP, 100 MLProducts: ASTMADIN 200 MG 150 ML SURUP, DIFILIN 300 MG/ 3 ML I.M. ENJEKSİYONLUK ÇÖZELTİ, 100 AMPULPipotiazine
go.drugbank.com/drugs/DB01621ApprovedInvestigationalWithdrawnHowever, it produces a high incidence of extra pyramidal reactions. It is used for the maintenance treatment of chronic non-agitated schizophrenic patients. … Among the different phenothiazine derivatives, it appears to be less sedating and to have a weak propensity for causing hypotension or potentiating the effects of CNS depressants and anesthetics.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 InhibitorsProducts: PIPORTIL ® L-4SOLUCION INYECTABLE AL 2.5% (100 MG)., TRIPIPOT® SOLUCIÓN INYECTABLE 25 MG/MLPermethrin
go.drugbank.com/drugs/DB04930ApprovedInvestigationalA pyrethroid insecticide commonly used in the treatment of lice infestations and scabies. It is a yellow to light orange-brown, low melt-ing solid or viscous liquid.
Categories: Compounds used in a research, industrial, or household setting, Cytochrome P-450 SubstratesProducts: NIKSEN 150 ML SAMPUAN, METRIN % 5 LOSYON,120 MLOxaliplatin
go.drugbank.com/drugs/DB00526ApprovedInvestigationalOxaliplatin is a platinum-based chemotherapy drug in the same family as cisplatin and carboplatin. … Compared to cisplatin the two amine groups are replaced by diamino cyclohexane (DACH) group to provide a greater antitumor effect.
Categories: OCT2 Substrates with a Narrow Therapeutic IndexSynonyms: L-OHP