Search

Displaying results 991 - 1000 of 10000 in total
  1. Target

    Hydroxymycolate synthase MmaA4

    go.drugbank.com/bio_entities/BE0003863
    TargetMycobacterium tuberculosis

    Probably transfers a methyl group from the S-adenosylmethionine (SAM) cofactor and, subsequently or simultaneously, a water molecule onto the double bound of ethylene substrates, leading to the formation

    Synonyms: S-adenosylmethionine-dependent methyltransferase
  2. Target

    Cyanocobalamin reductase / alkylcobalamin dealkylase

    go.drugbank.com/bio_entities/BE0002175
    TargetHumans

    Cobalamin (vitamin B12) cytosolic chaperone that catalyzes the reductive decyanation of cyanocob(III)alamin (cyanocobalamin, CNCbl) to yield cob(II)alamin and cyanide, using FAD or FMN as cofactors and NADPH as cosubstrate (PubMed:187795...

    Synonyms: Alkylcobalamin:glutathione S-alkyltransferase
  3. Drug

    Grape seed oil

    go.drugbank.com/drugs/DB14323
    Investigational

    Grape seed oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

    Synonyms: European Grape Seed Oil
  4. Drug

    Azithromycin

    go.drugbank.com/drugs/DB00207
    ApprovedInvestigational

    In March 2020, a small study was funded by the French government to investigate the treatment of COVID-19 with a combination of azithromycin and the anti-malaria drug [hydroxychloroquine]. … It is structurally related to erythromycin [A174169].

    Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: ZITHROMAX TR-SAFT K B 25KG, AZYTER 15 MG/G TEK DOZLUK GOZ DAMLASI, 6 ADET
  5. Target

    Eukaryotic peptide chain release factor GTP-binding subunit ERF3A

    go.drugbank.com/bio_entities/BE0004448
    TargetHumans

    GTPase component of the eRF1-eRF3-GTP ternary complex, a ternary complex that mediates translation termination in response to the termination codons UAA, UAG and UGA (PubMed:15987998, PubMed:19417105, PubMed:2511002, PubMed:27863242). GS...

    Synonyms: G1 to S phase transition protein 1 homolog
  6. Drug

    Pemetrexed

    go.drugbank.com/drugs/DB00642
    ApprovedInvestigational

    Pemetrexed is a chemotherapy drug that is manufactured and marketed by Eli Lilly and Company under the brand name Alimta. … Pemetrexed was first approved by the FDA in February 4, 2004.[A253907]

    Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingProducts: TEC PRED, PEMETREXED 500 MG POLVO LIOFILIZADO PARA SOLUCIÓN DE INFUSIÓN.
  7. Drug

    Eucalyptol

    go.drugbank.com/drugs/DB03852
    ApprovedInvestigationalNutraceutical

    Eucalyptol is naturally produced cyclic ether and monoterpenoid. Eucalyptol is an ingredient in many brands of mouthwash and cough suppressant. … Eucalyptol is an effective treatment for nonpurulent rhinosinusitis. Eucalyptol reduces inflammation and pain when applied topically. It kills leukaemia cells in vitro.

    Synonyms: 1,8-epoxy-p-menthane, 1,8-oxido-p-menthaneMixtures: Aurora Blue Mint, Aurora Fresh Burst
  8. Drug

    Tozasertib

    go.drugbank.com/drugs/DB19675
    Investigational

    Tozasertib is under investigation in clinical trial NCT02532868 (A VX-680 (an Aurora Kinase Inhibitor) Study in Patients With Advanced Cancer (0457-002)). … Tozasertib is a small molecule drug. The usage of the INN stem '-sertib' in the name indicates that Tozasertib is a serine/threonine kinase inhibitor.

    Categories: Heterocyclic Compounds, 1-Ring
  9. Drug

    Sodium chloride

    go.drugbank.com/drugs/DB09153
    ApprovedInvestigationalVet approved

    Sodium chloride is the primary salt in seawater and in the extracellular fluid of many multicellular organisms. It is listed on the World Health Organization Model List of Essential Medicines. … Sodium chloride, also known as salt, common salt, table salt or halite, is an ionic compound with the chemical formula NaCl, representing a 1:1 ratio of sodium and chloride ions.

    Mixtures: B S S STERILE IRRIGATING SOLUTION, D-5-SProducts: CLORURO DE SODIO DE 2 MEQ/ML SOLUCIÓN INYECTABLE, BERKO-FIZ % 0,9 NAZAL ÇÖZELTI IÇEREN TEK KULLANIMLIK FLAKON, 5 ADET
  10. Drug

    Dextropropoxyphene

    go.drugbank.com/drugs/DB00647
    ApprovedIllicitWithdrawn

    Due to the risk of cardiac arrhythmias and overdose, possibly leading to death, dextropropoxyphene has been withdrawn from the market in Europe and the United States. … The drug is often referred to as the general form, "propoxyphene", however only the dextro-isomer (dextropropoxyphene) has any analgesic effect.

    Synonyms: d-PropoxypheneMixtures: Darvocet-N 50, Darvocet-N 100