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Displaying results 991 - 1000 of 10000 in total
  1. Indication

    Not a candidate for surgery

    go.drugbank.com/conditions/DBCOND0144299
    Drugs: Pembrolizumab · Spironolactone · Vimseltinib
    Synonyms: Not a candidate for surgery
  2. Indication

    HLA-A*02:06 positive

    go.drugbank.com/conditions/DBCOND0168342
    Drugs: Afamitresgene autoleucel
    Synonyms: HLA-A*02:06 positive
  3. Drug

    Butylene glycol

    go.drugbank.com/drugs/DB14110
    Approved

    Mixtures: Skin Renewal, HydroGold 9Products: Dr.g A-clear Balancing Toner, DR.G A-CLEAR SPOT Repairing SERUM
  4. Target

    L-lactate dehydrogenase A-like 6A

    go.drugbank.com/bio_entities/BE0000297
    TargetHumans

    Catalyzes the interconversion of L-lactate and pyruvate with nicotinamide adenine dinucleotide NAD(+) as a coenzyme (PubMed:18351441).

    Polypeptides: L-lactate dehydrogenase A-like 6A
  5. Target

    D-alanine--D-alanine ligase A

    go.drugbank.com/bio_entities/BE0000733
    TargetEscherichia coli (strain K12)

    Cell wall formation.

    Polypeptides: D-alanine--D-alanine ligase ASynonyms: D-Ala-D-Ala ligase A, D-alanylalanine synthetase A
  6. Target

    Peptidyl-prolyl cis-trans isomerase A

    go.drugbank.com/bio_entities/BE0001014
    TargetHumans

    Inhibits replication of influenza A virus (IAV) (PubMed:19207730). … Exerts a strong chemotactic effect on leukocytes partly through activation of one of its membrane receptors BSG/CD147, initiating a signaling cascade that culminates in MAPK/ERK activation (PubMed:11943775

    Polypeptides: Peptidyl-prolyl cis-trans isomerase ASynonyms: PPIase A, Rotamase A
  7. Target

    Ribosomal small subunit pseudouridine synthase A

    go.drugbank.com/bio_entities/BE0001276
    TargetHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

    Responsible for synthesis of pseudouridine from uracil-516 in 16S ribosomal RNA.

    Polypeptides: Ribosomal small subunit pseudouridine synthase ASynonyms: rRNA-uridine isomerase A, rRNA pseudouridylate synthase A
  8. Target

    Methane monooxygenase component A alpha chain

    go.drugbank.com/bio_entities/BE0003331
    TargetEnzymeMethylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath)

    It also catalyzes the monohydroxylation of a variety of unactivated alkenes, alicyclic, aromatic and heterocyclic compounds.

    Polypeptides: Methane monooxygenase component A alpha chain
  9. Target

    DNA polymerase epsilon catalytic subunit A

    go.drugbank.com/bio_entities/BE0003614
    TargetHumans

    Along with DNA polymerase POLD1 and DNA polymerase POLK, has a role in excision repair (NER) synthesis following UV irradiation (PubMed:20227374)

    Polypeptides: DNA polymerase epsilon catalytic subunit ASynonyms: DNA polymerase II subunit A
  10. Drug

    Phenylephrine

    go.drugbank.com/drugs/DB00388
    ApprovedInvestigational

    Phenylephrine is an alpha-1 adrenergic receptor agonist used to treat hypotension,[L9416,L9410] dilate the pupil,[L9413] and induce local vasoconstriction. … [A187370] The action of phenylephrine, or neo-synephrine, was first described in literature in the 1930s.[A187376] Phenylephrine was granted FDA approval in 1939.[L9413]

    Synonyms: l-(3-Hydroxyphenyl)-N-methylethanolamine, (−)-m-hydroxy-α-(methylaminomethyl)benzyl alcoholInternational brands: AK-Dilate, AK-Nefrin