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Protamine
go.drugbank.com/drugs/DB13700ApprovedInvestigationalWithdrawnProducts: PROTAMYN 1000® UI/ML AMPOLLA, /ml - InjektionslösungCabozantinib
go.drugbank.com/drugs/DB08875ApprovedInvestigationalCabozantinib was first approved in 2012 and is a non-specific tyrosine kinase inhibitor. … [L15123] In 2016, a capsule formulation (Cabometyx) was approved for the treatment of advanced renal cell carcinoma, and this same formulation gained additional approval in both the US and Canada in 2019
Categories: Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexProducts: CABOMETYX 20 MG FİLM KAPLI TABLET, 30 ADET, CABOMETYX 40 MG FİLM KAPLI TABLET, 30 ADETDupilumab
go.drugbank.com/drugs/DB12159ApprovedInvestigational[L7186,L7192,L41439] Dupilumab is currently under investigations for potential therapeutic use in diseases driven by allergic reactions or type 2 inflammation, such as pediatric atopic dermatitis, and … [A180478] As an interleukin-4 receptor alpha antagonist, dupilumab inhibits the signaling of pro-inflammatory cytokines, called interleukins (IL), that induce inflammatory and immunological reactions in
Categories: Interleukin-4 Receptor alpha Antagonist, Interleukin 4 Receptor alpha AntagonistsProducts: Dupixent 175 mg/ml Enjeksiyonluk Çözelti İçeren Kullanıma Hazır Enjektör, 6 ADET, DUPİXENT 200 mg/1,14 ml ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 2 ADETDexchlorpheniramine maleate
go.drugbank.com/drugs/DB09555ApprovedDexchlorpheniramine is the S-enantiomer of chlorpheniramine which is a 1st generation anti-histamine. … Dexchlorpheniramine has more pharmacological activity than the R and so is more potent than the racemic mixture.
Mixtures: HUFADEXTA-M, Rescon MXCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 InhibitorsJosamycin
go.drugbank.com/drugs/DB01321InvestigationalA macrolide antibiotic from Streptomyces narbonensis. The drug has antimicrobial activity against a wide spectrum of pathogens.
Synonyms: Turimycin A5, leucomycin V 3-acetate 4B-(3-methylbutanoate)Products: Josalid 250 mg/5 ml - Saft für Kinder, Josalid 375 mg/5 ml - Saft für KinderBetaxolol
go.drugbank.com/drugs/DB00195ApprovedInvestigationalA cardioselective beta-1-adrenergic antagonist with no partial agonist activity.
Categories: Cytochrome P-450 Substrates, Adrenergic beta-1 Receptor AntagonistsSynonyms: 1-(4-(2-(cyclopropylmethoxy)ethyl)phenoxy)-3-((1-methylethyl)amino)-2-propanol, 1-(isopropylamino)-3-[p-(cyclopropylmethoxyethyl)phenoxy]-2-propanolUrapidil
go.drugbank.com/drugs/DB12661InvestigationalUrapidil has been investigated for the treatment of Hypertension During Pre-Eclampsia.
Categories: Peripheral alpha-1 blockers, Heterocyclic Compounds, 1-RingProducts: UPADİL 25 MG/5 ML IV ENJEKSİYONLUK ÇÖZELTİ, 5 ADET, PİDİLAX 25 MG/5 ML IV ENJEKSİYONLUK ÇÖZELTİ, 5 ADETSimoctocog alfa
go.drugbank.com/drugs/DB09108ApprovedIt is an antihemorrhagic agent used as a replacement therapy in individuals with Haemophilia A who lack the factor VIII in the intrinsic pathway of blood coagulation system. … Simoctocog alfa is a recombinant B-domain deleted (BDD) rFVIII produced in genetically modified human embryonic kidney (HEK) 293F cells.
Products: NUWIQ 500 UI, NUWIQ 2000 UIClotrimazole
go.drugbank.com/drugs/DB00257ApprovedInvestigationalVet approvedThis drug is a broad spectrum antimycotic or antifungal agent. Clotrimazole's antimycotic properties were discovered in the late 1960s [A174094]. … As well as its antifungal activity, clotrimazole has become a drug of interest in treating several other diseases such as sickle cell disease, malaria and some cancers [A174094].
Mixtures: Imazol duo 10 mg/g + 2,5 mg/g Creme, LINDAZOL-2 ®Categories: P-glycoprotein inducers, P-glycoprotein inhibitors