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Hydrocortisone
go.drugbank.com/drugs/DB00741ApprovedInvestigationalVet approved[L10529,L10532,L10535,L10538,L7772,L7321] It was discovered in the 1930s by Edward Kendall and named Compound F, or 17-hydroxycorticosterone. … Hydrocortisone, or cortisol, is a glucocorticoid secreted by the adrenal cortex.[A188387] Hydrocortisone is used to treat immune, inflammatory, and neoplastic conditions.
Mixtures: OLIVIA QUIDO FIRM and FADE I, OLIVIA QUIDO FIRM and FADE IICategories: Corticosteroids, Weak (Group I)Nasal Polyps
go.drugbank.com/conditions/DBCOND0004147Drugs: BudesonideSynonyms: Polyp in anterior naresFutibatinib
go.drugbank.com/drugs/DB15149ApprovedInvestigationalFGFR was investigated in oncology as a therapeutic target, as FGFR genomic aberrations and dysregulated FGFR signalling pathways are observed in some cancers such as cholangiocarcinoma and urothelial malignancies … Futibatinib is an inhibitor of Fibroblast Growth Factor receptor (FGFR), which comprises a group of receptor tyrosine kinases that play a key role in cell proliferation, differentiation, migration, and
Synonyms: 1-[(3S)-3-{4-amino-3-[(3,5-dimethoxyphenyl)ethynyl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl}pyrrolidin-1-yl]prop-2-en-1-oneChronic Phase Chronic Myeloid Leukemia
go.drugbank.com/conditions/DBCOND0057382Synonyms: CML in Chronic Phase, Chronic Myeloid Leukemia in Chronic PhaseHydroquinone
go.drugbank.com/drugs/DB09526ApprovedInvestigationalAs a result of these concerns, hydroquinone has been banned in the EU and UK. … It can be used alone, but is more frequently found in combination with other agents such as alpha-hydroxy acids, corticosteroids, retinoids, or sunscreen.
Mixtures: I-max Lightening 5, Continuum Unifying Lotion ICategories: Compounds used in a research, industrial, or household settingDinutuximab
go.drugbank.com/drugs/DB09077ApprovedInvestigationalneuroblastoma who achieve at least a partial response to prior first-line multiagent, multimodality therapy. … Despite a high clinical response seen after first-line treatment, the complete eradication of neuroblastoma is rarely achieved and the majority of patients with advanced disease suffer a relapse.
Stromal cell-derived factor 1
go.drugbank.com/bio_entities/BE0001150TargetHumansInhibits CXCR4-mediated infection by T-cell line-adapted HIV-1 (PubMed:8752281). Plays a protective role after myocardial infarction. … Induces down-regulation and internalization of ACKR3 expressed in various cells.
Synonyms: Intercrine reduced in hepatomasPoliovirus type 1 antigen (formaldehyde inactivated)
go.drugbank.com/drugs/DB10795ApprovedInvestigationalThe vaccine contains purified and inactivated poliovirus type 1 that were grown from a continuous line of monkey kidney cells. … Poliovirus type 1 antigen is a suspension of poliovirus Type 1 (Mahoney) used in the active immunization of infants (as young as 6 weeks of age), children, and adults for the prevention of poliomyelitis
Synonyms: Inactivated poliovirus type IMixtures: VeroPol Injektionslösung in einer Fertigspritze, -POLIO SUSPENSION FOR INJECTION IN PRE-FILLED SYRINGETyrosine
go.drugbank.com/drugs/DB00135ApprovedInvestigationalNutraceuticalTyrosine is a non-essential amino acid. In animals it is synthesized from [phenylalanine]. It is also the precursor of [epinephrine], thyroid hormones, and melanin.
Mixtures: AMINOPLASMAL 15% IN 500ML GLASS BOTTLE, 5% Travasol Amino Acid Injection With Electrolytes In 20% DextroseNuclear factor NF-kappa-B p100 subunit
go.drugbank.com/bio_entities/BE0002387TargetHumansNF-kappa-B complexes are held in the cytoplasm in an inactive state complexed with members of the NF-kappa-B inhibitor (I-kappa-B) family. … In a conventional activation pathway, I-kappa-B is phosphorylated by I-kappa-B kinases (IKKs) in response to different activators, subsequently degraded thus liberating the active NF-kappa-B complex which
Synonyms: Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2