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Tremelimumab
go.drugbank.com/drugs/DB11771ApprovedInvestigationalCTLA-4 is a cell surface receptor expressed on activated T cells to act as a negative regulator for T cells. … [A253717, L43652] Because CTLA-4 is an immune checkpoint that plays a vital role in regulating T cell-mediated immune response, tremelimumab is considered an immune checkpoint inhibitor, which is an emerging
Categories: CTLA-4-directed Blocking AntibodyProducts: Imjudo Concentrate for Solution for Intravenous Infusion 20 mg/mL, Imjudo 300 mg/15 ml İnfüzyonluk Çözelti Hazırlamak İçin Konsantre, 1 adetHeparin
go.drugbank.com/drugs/DB01109ApprovedInvestigationalUH is different from low molecular weight heparin (LMWH) in the following ways: the average molecular weight of LMWH is about 4.5 kDa whereas it is 15 kDa for UH; UH requires continuous infusions; activated … It is a naturally occurring anticoagulant released from mast cells.
Mixtures: NOSKAR 100 MG/50 IU/10 MG / G, JEL 50 G, NOSKAR 100 MG/50 IU/10 MG / G, JEL 120 GProducts: Unihepa 1000 IU/ ml Injection (5 ml vial), ./100 g - GelPhentermine
go.drugbank.com/drugs/DB00191ApprovedIllicitInvestigational[A174361, A174364] It is chemically related to amphetamine and it is commonly referred to as an atypical amphetamine. … Phentermine is a sympathomimetic amine anorectic agent and it was introduced in 1959 as part of an anti-obesity combination drug.
International brands: Obestin-30Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesClomifene
go.drugbank.com/drugs/DB00882ApprovedInvestigationalA triphenyl ethylene stilbene derivative which is an estrogen agonist or antagonist depending on the target tissue.
Synonyms: 2-(4-(2-chloro-1,2-diphenylethenyl)phenoxy)-N,N-diethylethanamine, 2-(p-(2-chloro-1,2-diphenylvinyl)phenoxy)triethylamineProducts: KLOMEN 50 MG TABLET, 10 ADET, KLOMEN 50 MG, 30 ADETOseltamivir
go.drugbank.com/drugs/DB00198ApprovedInvestigationalThe authors concluded that oseltamivir use in healthy adults had small, non-specific effects on symptoms (where the time to first alleviation of symptoms was only reduced from 7 to 6.3 days), it had no … They recommend the use of oseltamivir in people with a higher risk of developing complications including children younger than 2 years, people over 65 years, people with some chronic conditions or immunosuppression
Synonyms: Ethyl (3R,4R,5S)-4-acetamido-5-amino-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylate, 1-Cyclohexene-1-carboxylic acid, 4-(acetylamino)-5-amino-3-(1-ethylpropoxy)-, ethyl ester, (3R-(3alpha,4beta,5alpha))-Products: OSEFLU 30 MG GRANÜL İÇEREN SAŞE, 25 ADET, ENFLUVIR 30 MG SERT KAPSÜL, 10 ADETIcatibant
go.drugbank.com/drugs/DB06196ApprovedInvestigationalIcatibant is a synthetic decapeptide with 5 nonproteinogenic amino acid antagonist targeting the B<sub>2</sub> receptors with a similar affinity to bradykinin. … [A4017,A263041] It was investigated as a potential treatment of hereditary angioedema (HAE) as bradykinin was implicated in HAE swelling; specifically, mice lacking B<sub>2</sub> receptors showed reduced
Categories: Drugs Used in Hereditary AngioedemaProducts: ICATIBANT EG, Icatibant Reddy 30 mg/3 ml Injektionslösung in einer FertigspritzeFerrous fumarate
go.drugbank.com/drugs/DB14491ApprovedInvestigationalUsed in treatment of iron deficiency anemia.
Synonyms: Iron(2+) fumarateMixtures: Vitamin C 202,8 mg/0,8 mg/100 mg - Hartkapseln, FOLEX 308MG/350 MCG KAPLI TABLET, 100 ADETAcylcarnitine (5Z)-7-[(1R)-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopent-2-en-1-yl]hept-5-enoylcarnitine
smpdb.ca/view/SMP0123464Metabolicen-1-yl]-5-oxocyclopent-2-en-1-yl]hept-5-enoylcarnitine. … (5Z)-7-[(1R)-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopent-2-en-1-yl]hept-5-enoylcarnitine is an acylcarnitine.
Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 moreBrimonidine
go.drugbank.com/drugs/DB00484ApprovedInvestigational[A178951] It is considered to be a third generation alpha-2 aadrenergic receptor agonist, since it displays preferential binding at alpha-2 adrenoceptors over alpha-1 receptors. … Brimonidine is an alpha-adrenergic agonist and 2-imidazoline derivative that was first introduced in 1996.
Synonyms: 5-Bromo-6-(2-imidazolin-2-ylamino)quinoxalineMixtures: SİMBRİNZA 10 MG/ML + 2 MG/ML GÖZ DAMLASI, SÜSPANSİYON, 5 ML, SIMBRINZA EYE DROPS, SUSPENSION 10 MG/ML + 2 MG/MLMacitentan
go.drugbank.com/drugs/DB08932ApprovedInvestigationalMacitentan is a dual endothelin receptor antagonist used in the treatment of pulmonary arterial hypertension (PAH).[L35890] It was first approved by the FDA in 2013. … A combination product (Opsynvi) comprising macitentan and [tadalafil] was approved in Canada in October 2021 for the treatment of PAH.[L39105] It was subsequently approved by the FDA in March 2024.
Mixtures: OPSYNVI® (MACITENTAN/TADALAFILO) 10MG/40 MG TABLETAS RECUBIERTASCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 Substrates