Search
Interleukin-10 receptor subunit beta
go.drugbank.com/bio_entities/BE0014312TargetHumansShared cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL28, and IFNL1. … The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity.
Polypeptides: Interleukin-10 receptor subunit betaSynonyms: IL-10 receptor subunit beta, Cytokine receptor class-II member 4TNF receptor-associated factor 6
go.drugbank.com/bio_entities/BE0021309TargetHumansAdapter protein that seems to play a role in signal transduction initiated via TNF receptor, IL-1 receptor and IL-17 receptor (PubMed:12140561, PubMed:19825828, PubMed:8837778).
Polypeptides: TNF receptor-associated factor 6G protein-coupled receptor 6
go.drugbank.com/bio_entities/BE0021832TargetHumansConstitutively active G protein-coupled receptor that maintains high cAMP levels and contributes to several processes including neuronal development, through activation of intracellular signaling pathways
Polypeptides: G protein-coupled receptor 6Synonyms: Sphingosine 1-phosphate receptor GPR6Pemigatinib
go.drugbank.com/drugs/DB15102ApprovedInvestigationalgrowth factor receptor 2 (FGFR2) gene fusion or other rearrangements as detected by an FDA-approved test. … With increasing research on the pathogenesis of cholangiocarcinoma and potential therapeutic targets for anticancer drug treatment, recent studies show that up to 45% of patients with intrahepatic cholangiocarcinoma
Categories: Fibroblast growth factor receptor (FGFR) tyrosine kinase inhibitors, Receptor, Fibroblast Growth Factor, Type 1, antagonists & inhibitorsProstaglandin E2 receptor EP1 subtype
go.drugbank.com/bio_entities/BE0000064TargetHumansReceptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(q) proteins which activate a phosphatidylinositol-calcium second messenger system.
Polypeptides: Prostaglandin E2 receptor EP1 subtypeSynonyms: PGE receptor EP1 subtype, Prostanoid EP1 receptorRetinoic acid receptor RXR-beta
go.drugbank.com/bio_entities/BE0000078TargetHumansReceptor for retinoic acid.
Polypeptides: Retinoic acid receptor RXR-betaSynonyms: Retinoid X receptor beta, Nuclear receptor subfamily 2 group B member 2Glutamate receptor ionotropic, kainate 1
go.drugbank.com/bio_entities/BE0000346TargetHumansThe receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist … Ionotropic glutamate receptor that functions as a cation-permeable ligand-gated ion channel, gated by L-glutamate and the glutamatergic agonist kainic acid.
Polypeptides: Glutamate receptor ionotropic, kainate 1Synonyms: Glutamate receptor 5, Excitatory amino acid receptor 3Prostaglandin E2 receptor EP2 subtype
go.drugbank.com/bio_entities/BE0000368TargetHumansReceptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. … The subsequent raise in intracellular cAMP is responsible for the relaxing effect of this receptor on smooth muscle
Polypeptides: Prostaglandin E2 receptor EP2 subtypeSynonyms: PGE receptor EP2 subtype, Prostanoid EP2 receptorRetinoic acid receptor RXR-alpha
go.drugbank.com/bio_entities/BE0000412TargetHumansReceptor for retinoic acid that acts as a transcription factor (PubMed:10874028, PubMed:11162439, PubMed:11915042, PubMed:37478846).
Polypeptides: Retinoic acid receptor RXR-alphaSynonyms: Retinoid X receptor alpha, Nuclear receptor subfamily 2 group B member 1Interleukin-11 receptor subunit alpha
go.drugbank.com/bio_entities/BE0000416TargetHumansReceptor for interleukin-11 (IL11). The receptor systems for IL6, LIF, OSM, CNTF, IL11 and CT1 can utilize IL6ST for initiating signal transmission.
Polypeptides: Interleukin-11 receptor subunit alphaSynonyms: IL-11 receptor subunit alpha