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Cyclopropane mycolic acid synthase 2
go.drugbank.com/bio_entities/BE0001211TargetMycobacterium tuberculosiscyclopropanated ketomycolate or methoxymycolate through the conversion of a double bond to a cyclopropane ring at the proximal position of an oxygenated mycolic acid via the transfer of a methylene group from S-adenosyl-L-methionine
Synonyms: S-adenosylmethionine-dependent methyltransferaseAdalimumab
go.drugbank.com/drugs/DB00051ApprovedInvestigationalA high-concentration, citrate-free formulation of Cyltezo® (adalimumab-adbm), a biosimilar to Humira®, was approved by the FDA in May 2024 for the treatment of multiple chronic inflammatory diseases. … [A39984,A39999] It was originally launched by Abbvie in the U.S. and approved in 2002 by the FDA.[A39983] This drug is frequently known as _Humira_.
Products: HUMIRA 40MG ILO I E FER, AMGEVITA 40MG ILO I E FERCyclopropane mycolic acid synthase 3
go.drugbank.com/bio_entities/BE0002521TargetMycobacterium tuberculosisCatalyzes the conversion of a double bond to a cyclopropane ring at the proximal position of an alpha mycolic acid via the transfer of a methylene group from S-adenosyl-L-methionine.
Synonyms: S-adenosylmethionine-dependent methyltransferaseMorphine
go.drugbank.com/drugs/DB00295ApprovedInvestigationalMorphine, the main alkaloid of opium, was first obtained from poppy seeds in 1805.[A176035] It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse. … [A176050] Morphine is still routinely used today, though there are a number of semi-synthetic opioids of varying strength such as [codeine], [fentanyl], [methadone], [hydrocodone], [hydromorphone], [meperidine
Synonyms: (7R,7AS,12bs)-3-methyl-2,3,4,4a,7,7a-hexahydro-1H-4,12-methano[1]benzofuro[3,2-e]isoquinoline-7,9-diol, (5R,6S,9R,13S,14R)-4,5-epoxy-N-methyl-7-morphinen-3,6-diolCategories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Cytochrome P-450 SubstratesNeuronal Acetylcholine (nACh) Receptor Subunits
go.drugbank.com/bio_entities/BE0009927TargetHumansby a collection of nAChR subunits. … Component of neuronal acetylcholine receptors (nAChRs) that function as pentameric, ligand-gated cation channels with high calcium permeability. nAChRs are excitatory neurotrasnmitter receptors formed
Synonyms: nAChR7, NACHR alpha-10Magnesium oxide
go.drugbank.com/drugs/DB01377ApprovedInvestigationalMagnesium oxide is an inorganic compound that occurs in nature as the mineral periclase. In aqueous media combines quickly with water to form magnesium hydroxide. … It is used as an antacid and mild laxative and has many nonmedicinal uses.
Mixtures: WOMEN`S MULTIVITE WITH EVENING PRIMROSE OIL,ROYAL JELLY & KOREAN GINSENG, Se-Natal OneProducts: MAGNEZI KALSINE 100 G TOZ, 100 GProstaglandin E synthase
go.drugbank.com/bio_entities/BE0011075TargetHumansTerminal enzyme of the cyclooxygenase (COX)-2-mediated prostaglandin E2 (PGE2) biosynthetic pathway. Catalyzes the glutathione-dependent oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2) in response to inf...
Synonyms: Microsomal glutathione S-transferase 1-like 1Risankizumab
go.drugbank.com/drugs/DB14762ApprovedInvestigational[L39885] It gained its first global approval in Japan in March 2019, followed by approval in Canada, the US, and Europe in April 2019. … [A254716] Risankizumab is used to treat plaque psoriasis, psoriatic arthritis, and Crohn's disease.[L39885,L44191,L44231] Risankizumab is being investigated for atopic dermatitis.[A254716]
Products: Skyrizi 150 mg/ml Enjeksiyonluk Çözelti İçeren Kullanıma Hazır Kalem, 1 ADET, SKYRİZİ 150 MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADETStannous fluoride
go.drugbank.com/drugs/DB11092ApprovedInvestigationalIt is an FDA-approved over-the-counter product. … Stannous Fluoride, or Tn(II) Fluoride, is a compound commonly used in toothpastes for the prevention of gingivitis, dental infections, cavities, and to relieve dental hypersensitivity.
Categories: Compounds used in a research, industrial, or household settingProducts: H E B Restore and Defend, Complete Protection TPDibotermin alfa
go.drugbank.com/drugs/DB11639ApprovedInvestigationalThrough enhancing osteogenesis at the site of implantation, dibotermin alfa accelerates the healing of open tibial shaft fractures and reduces the need for secondary intervention [A31945]. … BMPs are subfamily of the transforming growth factor-β (TGF-β) superfamily that have different actions on the bone matrix [A31946].
Synonyms: BMP 2, BMP-2