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Lincomycin
go.drugbank.com/drugs/DB01627ApprovedInvestigationalVet approvedLincomycin is a lincosamide antibiotic first isolated from the soil bacterium Streptomyces lincolnensis in Lincoln, Nebraska. Clinical use of lincomycin has largely been superseded by its semisynthetic derivative clindamycin due to its h...
Damoctocog alfa pegol
go.drugbank.com/drugs/DB14700ApprovedInvestigationalIn recent years, various extended half-life factor VIII and factor IX preparations have been studied and gained approval.
Remimazolam
go.drugbank.com/drugs/DB12404ApprovedInvestigational[L14647] Recent trends in anesthesia-related drug development have touted the benefits of so-called "soft drugs" - these agents, such as [remifentanil], are designed to be metabolically fragile and thus
High affinity immunoglobulin epsilon receptor subunit alpha
go.drugbank.com/bio_entities/BE0000015TargetHumansHigh-affinity receptor for immunoglobulin epsilon/IgE. Mediates IgE effector functions in myeloid cells.
Polypeptides: High affinity immunoglobulin epsilon receptor subunit alphaSynonyms: IgE Fc receptor subunit alphaHigh affinity immunoglobulin gamma Fc receptor I
go.drugbank.com/bio_entities/BE0000710TargetCarrierHumansHigh affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses.
Polypeptides: High affinity immunoglobulin gamma Fc receptor ISynonyms: IgG Fc receptor IGamma-aminobutyric acid receptor subunit alpha-6
go.drugbank.com/bio_entities/BE0000764TargetHumansAlpha subunit of the heteropentameric ligand-gated chloride channel gated by gamma-aminobutyric acid (GABA), a major inhibitory neurotransmitter in the brain (PubMed:8632757). GABA-gated chloride channels, also named GABA(A) receptors (G...
Polypeptides: Gamma-aminobutyric acid receptor subunit alpha-6Synonyms: GABA(A) receptor subunit alpha-6Tyrosine-protein phosphatase non-receptor type 4
go.drugbank.com/bio_entities/BE0000980TargetHumansPhosphatase that plays a role in immunity, learning, synaptic plasticity or cell homeostasis (PubMed:25825441, PubMed:27246854). Regulates neuronal cell homeostasis by protecting neurons against apoptosis (PubMed:20086240). Negatively re...
Polypeptides: Tyrosine-protein phosphatase non-receptor type 4Tumor necrosis factor receptor superfamily member 1A
go.drugbank.com/bio_entities/BE0001139TargetHumansReceptor for TNFSF2/TNF and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor.
Polypeptides: Tumor necrosis factor receptor superfamily member 1ASynonyms: Tumor necrosis factor receptor 1, Tumor necrosis factor receptor type ITriggering receptor expressed on myeloid cells 1
go.drugbank.com/bio_entities/BE0001288TargetHumansBy also promoting the amplification of inflammatory signals that are initially triggered by Toll-like receptor (TLR) and NOD-like receptor engagement, plays a major role in the pathophysiology of acute … Cell surface receptor that plays important roles in innate and adaptive immunity by amplifying inflammatory responses (PubMed:10799849, PubMed:21393102).
Polypeptides: Triggering receptor expressed on myeloid cells 1Synonyms: Triggering receptor expressed on monocytes 1Gamma-aminobutyric acid receptor subunit beta-1
go.drugbank.com/bio_entities/BE0002344TargetHumansBeta subunit of the heteropentameric ligand-gated chloride channel gated by gamma-aminobutyric acid (GABA), a major inhibitory neurotransmitter in the brain (PubMed:10449790, PubMed:16412217, PubMed:26950270). GABA-gated chloride channel...
Polypeptides: Gamma-aminobutyric acid receptor subunit beta-1Synonyms: GABA(A) receptor subunit beta-1