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Displaying results 1041 - 1050 of 10000 in total
  1. Target

    Sodium/iodide cotransporter

    go.drugbank.com/bio_entities/BE0009346
    TargetTransporterHumans

    Can also mediate the transport of chlorate, thiocynate, nitrate and selenocynate (PubMed:12488351)

    Synonyms: Na(+)/I(-) symporter, Na(+)/I(-) cotransporter
  2. Drug

    PRGN-3006

    go.drugbank.com/drugs/DB17229
    Investigational

    PRGN-3006 are autologous CD3+ T cells genetically modified using a non-viral system to express a CD33 CAR, membrane-bound interleukin-15, and a truncated form of human HER1T (kill switch) on the cell surface

    Synonyms: Autologous CD3+ T cells genetically modified using a non-viral system to express a CD33 CAR, membrane bound Interleukin-15, and a truncated form of human HER1t (kill switch) on the cell surface, PRGN-3006 UltraCAR-T
  3. Drug

    Inositol

    go.drugbank.com/drugs/DB13178
    ApprovedInvestigationalWithdrawn

    [L2560] Inositol can be found as an ingredient of OTC products by Health Canada but all current product whose main ingredient is inositol are discontinued. … Inositol is a collection of nine different stereoisomers but the name is usually used to describe only the most common type of inositol, myo-inositol.

    Mixtures: Super Daily No 2, Vitamin B + C CapCategories: Vitamin B Complex
  4. Drug

    Quetiapine

    go.drugbank.com/drugs/DB01224
    ApprovedInvestigational

    Initially approved by the FDA in 1997, quetiapine is a second-generation atypical antipsychotic used in schizophrenia, major depression, and bipolar disorder. … It is well-tolerated and a suitable option for some patients with high sensitivity to other drugs, such as [clozapine] and [olanzapine].[A2189]

    Mixtures: Quetialan 4 Tage Startpackung - Filmtabletten, Seroquel 4-Tage Startpackung FilmtablettenCategories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, P-glycoprotein substrates
  5. Pathway

    Acylcarnitine (2Z)-2-(propan-2-yl)but-2-enedioylcarnitine

    smpdb.ca/view/SMP0123554
    Metabolic

    This reaction can occur in both directions, and L-acetylcarnitine and CoA can react to form acetyl-CoA and L-carnitine in certain circumstances. … Acetyl-CoA can go on to enter the TCA cycle, or it can react with L-carnitine to form L-acetylcarnitine in a reaction catalyzed by Carnitine O-acetyltransferase.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
  6. Drug

    Centella asiatica leaf

    go.drugbank.com/drugs/DB14687
    Investigational

    Synonyms: Ji xue cao leaf
  7. Drug

    Tenofovir alafenamide

    go.drugbank.com/drugs/DB09299
    ApprovedInvestigational

    Tenofovir alafenamide is a novel [tenofovir] prodrug developed in order to improve renal safety when compared to the counterpart [tenofovir disoproxil]. … [T239] Tenofovir alafenamide is an alanine ester form characterized for presenting low systemic levels but high intracellular concentration.

    Mixtures: GENVOYA ® TABLETAS RECUBIERTAS, DESCOVY® 200MG/10MG TABLETAS RECUBIERTASCategories: Antivirals used in combination for the treatment of HIV infections, Vitamin B Complex
  8. Target

    CAI-1 autoinducer synthase

    go.drugbank.com/bio_entities/BE0004287
    TargetVibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

    Required for the synthesis of the quorum-sensing autoinducer CAI-1 ((S)-3-hydroxytridecan-4-one) which probably functions as an intragenus signal.

    Polypeptides: CAI-1 autoinducer synthase
  9. Drug

    Strontium ranelate

    go.drugbank.com/drugs/DB09267
    ApprovedWithdrawn

    Available for prescription use for a time in some parts of the world as Protelos (strontium ranelate) 2 g granules for oral suspension by Servier, it was ultimately discontinued in 2016-2017 owing to an … Some reports have shown that strontium ranelate can slow down the progression of osteoarthritis of the knee.

    Mixtures: FULLBONE D3 2 G/800 IU EFERVESAN TABLET, 30 ADET, FULLBONE D3 2 G/800 IU EFERVESAN TABLET, 60 ADETCategories: Heterocyclic Compounds, 1-Ring
  10. Drug

    Phenelzine

    go.drugbank.com/drugs/DB00780
    ApprovedInvestigational

    [A15753] It was developed by Parke Davis and originally FDA approved on June 9th, 1961. It is currently approved under prescription by the name of Nardil. … Phenelzine, with the formula β-phenylethylhydrazine, is a monoamine oxidase inhibiting antidepressant that is effective in the treatment of panic disorder and social anxiety disorder.

    Categories: Monoamine Oxidase Inhibitors, Non-Selective, Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome