Search

Displaying results 1041 - 1050 of 10000 in total
  1. Drug

    Carvedilol

    go.drugbank.com/drugs/DB01136
    ApprovedInvestigational

    Carvedilol is a racemic mixture where the S(-) enantiomer is both a beta and alpha-1 adrenoceptor blocker, and the R(+) enantiomer is an alpha-1 adrenoceptor blocker. … [L7889,L7892] It is currently used to treat heart failure, left ventricular dysfunction, and hypertension.

    Mixtures: Co-Dilatrend 25 mg/12,5 mg - Filmtabletten, CARIVALAN 25/5Categories: Compounds used in a research, industrial, or household setting, P-glycoprotein inhibitors
  2. Pathway

    Congenital Lipoid Adrenal Hyperplasia (CLAH) or Lipoid CAH

    smpdb.ca/view/SMP0000371
    Disease

    Congenital Lipoid Adrenal Hyperplasia (CLA),also called steroid 20-22 desmolase deficiency and lipoid CAH, is an autosomal recessive disorder and caused by a defective cholesterol side-chain cleavage enzyme

    Drugs: NADH · Progesterone · Hydrocortisone · Mesoheme · Cholesterol · Corticosterone +1 more
  3. Pathway

    Congenital Lipoid Adrenal Hyperplasia (CLAH) or Lipoid CAH

    smpdb.ca/view/SMP0125798
    Disease

    Congenital Lipoid Adrenal Hyperplasia (CLA),also called steroid 20-22 desmolase deficiency and lipoid CAH, is an autosomal recessive disorder and caused by a defective cholesterol side-chain cleavage enzyme

    Drugs: NADH · Progesterone · Hydrocortisone · Mesoheme · Cholesterol · Corticosterone +1 more
  4. Drug

    Selenium

    go.drugbank.com/drugs/DB11135
    ApprovedInvestigationalVet approved

    Selenium is a trace metal in the human body particularly important as a component of glutathione peroxidase, an important enzyme in the prevention of cellular damage by free radicals and reactive oxygen

    Mixtures: Vitamine E 400 Ui and Selenium 50, Webber E Plus 3 CapCategories: Compounds used in a research, industrial, or household setting
  5. Drug

    Azithromycin

    go.drugbank.com/drugs/DB00207
    ApprovedInvestigational

    In March 2020, a small study was funded by the French government to investigate the treatment of COVID-19 with a combination of azithromycin and the anti-malaria drug [hydroxychloroquine]. … Azithromycin is a broad-spectrum macrolide antibiotic with a long half-life and a high degree of tissue penetration [A174172]. It was initially approved by the FDA in 1991 [A174175].

    Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: Zithromax Cap 250mg, ZITHROMAX TR-SAFT K B 25KG
  6. Drug

    Trimethoprim

    go.drugbank.com/drugs/DB00440
    ApprovedInvestigationalVet approved

    [L11893] Trimethoprim is often used in combination with [sulfamethoxazole] due to their complementary and synergistic mechanisms but may be used as a monotherapy in the treatment and/or prophylaxis of … Trimethoprim is an antifolate antibacterial agent that inhibits bacterial dihydrofolate reductase (DHFR), a critical enzyme that catalyzes the formation of tetrahydrofolic acid (THF) - in doing so, it

    Mixtures: EUSAPRIM K SUS F KDR, TRIMETROPINA SULFA F MKCategories: MATE 1 Inhibitors, MATE 1 Substrates
  7. Drug

    Edoxudine

    go.drugbank.com/drugs/DB13421
    ApprovedWithdrawn

    It was later recognized to be effective in vivo in a preclinical model of keratitis caused by herpes virus. … [A32643] It was developed by McNeil Pharmaceutical and approved by Health Canada on December 31, 1992. This medication was later discontinued from the market in 1998.[L1113]

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 2'-Deoxy-5-ethyluridine, 5-Ethyl-2'-deoxyuridine
  8. Indication

    Migraine With Aura

    go.drugbank.com/conditions/DBCOND0031385
    Drugs: Eletriptan · Frovatriptan · Meloxicam · Rimegepant · Rizatriptan · Ubrogepant
    Synonyms: Möbius' syndrome I
  9. Drug

    Moxifloxacin

    go.drugbank.com/drugs/DB00218
    ApprovedInvestigational

    Bayer AG developed the drug (initially called BAY 12-8039) and it is marketed worldwide (as the hydrochloride) under the brand name Avelox (in some countries also Avalox) for oral treatment. … Moxifloxacin is a synthetic fluoroquinolone antibiotic agent.

    Mixtures: TQ OFTAMOX D UD®, TQ OFTAMOX® D UDCategories: Topoisomerase II Inhibitors, 4-Quinolones
  10. Drug

    Mirtazapine

    go.drugbank.com/drugs/DB00370
    ApprovedInvestigational

    [A177946] This drug was first manufactured by Organon Inc., and received FDA approval in 1997 for the treatment of major depressive disorder. … [A178144,L6160] In addition to its beneficial effects in depression, mirtazapine has been reported to be efficacious in the off-label management of various other conditions.

    Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Cytochrome P-450 SubstratesSynonyms: 1,2,3,4,10,14b-Hexahydro-2-methylpyrazino(2,1-a)pyrido(2,3-c)benzazepine, 6-Azamianserin