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Displaying results 1041 - 1050 of 7181 in total
  1. Pathway

    Acylcarnitine (2Z)-2-(propan-2-yl)but-2-enedioylcarnitine

    smpdb.ca/view/SMP0123554
    Metabolic

    -yl)but-2-enedioylcarnitine from forming and thereby preventing it from being transported into the mitochondria. … The general role of acylcarnitines is to transport acyl-groups, organic acids and fatty acids, from the cytoplasm into the mitochondria so that they can be broken down to produce energy.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
  2. Drug

    Elasomeran

    go.drugbank.com/drugs/DB15654
    ApprovedInvestigational

    COVID-19 has high interpatient variability in symptoms, ranging from mild symptoms to severe illness. … In clinical trials, there were no differences in the safety profiles between younger and older (65 years of age and older) study participants.

  3. Drug

    Quinagolide

    go.drugbank.com/drugs/DB09097
    ApprovedWithdrawn

    These drugs are effective in patients who are intolerant or resistant to [DB01200]. … Quinagolide is currently available in several countries including Canada, but not approved for treatment in the United States.

    Synonyms: (+-)-N,N-Diethyl-N'-((3R*,4aR*,10aS*)-1,2,3,4,4a,5,10,10a-octahydro-6-hydroxy-1-propylbenzo(g)quinolin-3-yl)sulfamide
  4. Drug

    Technetium Tc-99m

    go.drugbank.com/drugs/DB14227
    Investigational

    Technetium-99m is the metastable isotope of technetium. It is commonly symbolized as 99mTc and used in the area of medical diagnosis. Technetium-99m is the most commonly used medical radioisotope.

    Synonyms: Tc 99, Technetium Tc 99mProducts: TECHNECIUM TC 99M GENERADOR
  5. Indication

    Stomach cramps

    go.drugbank.com/conditions/DBCOND0101060
    Drugs: Pinaverium · Simethicone
    Synonyms: Pain localized to upper abdomen
  6. Drug

    Coral snake (micrurus fulvius) immune globulin antivenin (equine)

    go.drugbank.com/drugs/DB13883
    Approved

    The antivenin is a refined, concentrated, and lyophilized preparation of serum globulins obtained by fractionating blood from healthy horses that have been immunized with eastern coral snake (Micrurus … It is intravenously administered so that the antivenin binds to and neutralizes coral snake venom.

  7. Drug

    Xenon Xe-129

    go.drugbank.com/drugs/DB17386
    ApprovedInvestigational

    They undergo a process that increases nuclear polarization up to five orders of magnitude, leading to a higher MRI signal. … [Helium-3] (He-3) is the one most commonly used due to its strong signal and favorable safety profile, but its use in other applications has affected its availability.

  8. Drug

    Pegaptanib

    go.drugbank.com/drugs/DB04895
    ApprovedWithdrawn

    Pegatinib aids neovascular age-related macular degeneration by binding to VEGF which in order reduces angiogenesis and vessel permeability. Pegaptanib was granted FDA approval on 17 September 2004.

  9. Drug

    Bamlanivimab

    go.drugbank.com/drugs/DB15718
    ApprovedInvestigational

    Bamlanivimab (LY-CoV555, also known as LY3819253), is a synthetic monoclonal antibody (mAb) derived from one of the first blood samples in the United States from a patient who recovered from COVID-19. … [A224044, L20974] It is set to enter phase 3 clinical trials.

  10. Drug

    Pepsin

    go.drugbank.com/drugs/DB13198
    ApprovedWithdrawn

    Studies on gastric digestion from 1820-1840 led to the discovery of pepsin as the substance which, in the presence of stomach acid, causes nutrients including meat or coagulated egg whites to dissolve. … Soon afterward, it was shown that these protein nutrients were cleaved by pepsin to products called _peptones_ [A32603].

    Mixtures: Glutamic Acid Hydrochloride Nu Life