Search

Displaying results 1041 - 1050 of 10000 in total
  1. Drug

    Iodine povacrylex

    go.drugbank.com/drugs/DB09537
    Approved

    It is a broad spectrum antiseptic and can provide almost 99.9% antiseptic conditions. It is intended for local use only. … DuraPrep solution is indicated for use as a patient preoperative skin preparation, for the preparation of the skin prior to surgery and to help reduce bacteria that can potentially cause skin infection

  2. Drug

    Alprazolam

    go.drugbank.com/drugs/DB00404
    ApprovedIllicitInvestigational

    [A18125] Alprazolam's adverse effects are generally related to the sedation it can cause. … [A18125] Alprazolam has been mixed with alcohol as a drug of abuse to potentiate the sedative effects of the drug which may lead to coma and death.

    Synonyms: 8-Chloro-1-methyl-6-phenyl-4H-s-triazolo(4,3-a)(1,4)benzodiazepineMixtures: NEUPAX DUO-S
  3. Drug

    Perampanel

    go.drugbank.com/drugs/DB08883
    ApprovedInvestigational

    It is marketed under the name Fycompa™ and is indicated as an adjunct in patients over 12 years old for the treatment of partial-onset seizures that may or may not occur with generalized seizures. … The FDA label includes an important black-boxed warning of serious or life-threatening behavioral and psychiatric reactions in patients taking Fycompa™.

    Synonyms: 3-(2-Cyanophenyl)-5-(2-pyridyl)-1-phenyl-1,2-dihydropyridin-2-oneCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 Inducers
  4. Drug

    Ketamine

    go.drugbank.com/drugs/DB01221
    ApprovedInvestigationalVet approved

    Ketamine is an NMDA receptor antagonist with a potent anesthetic effect.[A31869] It was developed in 1963 as a replacement for phencyclidine (PCP) by Calvin Stevens at Parke Davis Laboratories. … It was FDA approved in 1970, and from there, it has been used as an anesthetic for children or patients undergoing minor surgeries but mainly for veterinary purposes.[L1332]

    Synonyms: 2-(2-Chloro-phenyl)-2-methylamino-cyclohexanone, 2-(methylamino)-2-(2-chlorophenyl)cyclohexanoneCategories: Cytochrome P-450 Substrates, N-Methylaspartate, agonists
  5. Drug

    Solifenacin

    go.drugbank.com/drugs/DB01591
    ApprovedInvestigational

    Solifenacin is a competitive muscarinic receptor antagonist indicated to treat an overactive bladder with urinary incontinence, urgency, and frequency. … [L7511] It has a long duration of action as it is usually taken once daily.[L7511] Solifenacin was granted FDA approval on 19 November 2004.[L7511]

    Mixtures: VESOMNI®, VESOMNİ 6 MG/0.4 MG DEĞİŞTİRİLMİŞ SALIMLI TABLET, 30 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A1 Substrates
  6. Drug

    Emapalumab

    go.drugbank.com/drugs/DB14724
    ApprovedInvestigational

    Emapalumab, also known as NI-0501, is a fully human monoclonal antibody that targets interferon gamma.

  7. Drug

    Lorazepam

    go.drugbank.com/drugs/DB00186
    ApprovedInvestigational

    Lorazepam is a short-acting and rapidly cleared benzodiazepine used commonly as a sedative and anxiolytic.

    Synonyms: o-Chloroxazepam, o-ChlorooxazepamProducts: ATIVAN® 1 MG TABLETAS, LORANS 1 TABLET 1 mg
  8. Target

    Baculoviral IAP repeat-containing protein 5

    go.drugbank.com/bio_entities/BE0003408
    TargetHumans

    May counteract a default induction of apoptosis in G2/M phase (PubMed:9859993). The acetylated form represses STAT3 transactivation of target gene promoters (PubMed:20826784). … May play a role in neoplasia (PubMed:10626797). Inhibitor of CASP3 and CASP7 (PubMed:21536684). Essential for the maintenance of mitochondrial integrity and function (PubMed:25778398).

    Polypeptides: Baculoviral IAP repeat-containing protein 5
  9. Target

    Baculoviral IAP repeat-containing protein 7

    go.drugbank.com/bio_entities/BE0010707
    TargetHumans

    May contribute to caspase inhibition, by blocking the ability of DIABLO/SMAC to disrupt XIAP/BIRC4-caspase interactions (PubMed:16729033).

    Polypeptides: Baculoviral IAP repeat-containing protein 7
  10. Drug

    Tea tree oil

    go.drugbank.com/drugs/DB11218
    ApprovedNutraceutical

    It may be referred to as _Melaleuca alternifolia_ oil. … Tea tree oil is an essential oil derived mainly from the Australian native plant _Melaleuca alternifolia_ via steam distillation of the of the leaves and terminal branches [A32439].

    Mixtures: I Dew Care Tea Tree O Starterkit