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Displaying results 1051 - 1060 of 10000 in total
  1. Target

    Prelamin-A/C

    go.drugbank.com/bio_entities/BE0010877
    TargetHumans

    Lamin A and C are present in equal amounts in the lamina of mammals (PubMed:10080180, PubMed:10580070, PubMed:10587585, PubMed:10814726, PubMed:11799477, PubMed:12075506, PubMed:12927431, PubMed:15317753 … Lamins provide a framework for the nuclear envelope, bridging the nuclear envelope and chromatin, thereby playing an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere

    Polypeptides: Prelamin-A/C
  2. Drug

    Carboplatin

    go.drugbank.com/drugs/DB00958
    ApprovedInvestigational

    Carboplatin is an organoplatinum antineoplastic alkylating agent used in the treatment of advanced ovarian carcinoma.[L32253] Early clinical studies of carboplatin were performed in 1982. … [A230523] Carboplatin was developed as an analog of [cisplatin] with reduced nephrotoxicity and vomiting.[A230463,A230523] Carboplatin was granted FDA approval on 3 March 1989.[L32248]

    Categories: Compounds used in a research, industrial, or household settingSynonyms: Cis-(1,1-cyclobutanedicarboxylato)diammineplatinum(II), Cis-diammine(1,1-cyclobutanedicarboxylato)platinum(II)
  3. Drug

    Salicylic acid

    go.drugbank.com/drugs/DB00936
    ApprovedInvestigationalVet approved

    A compound obtained from the bark of the white willow and wintergreen leaves, and also prepared synthetically. It has bacteriostatic, fungicidal, and keratolytic actions. … Its salts, the salicylates, are used as analgesics.

    Synonyms: 2-Carboxyphenol, O-carboxyphenolMixtures: Keeva 3 In 1 Acne Treatment, Keeva 3 In 1 Acne Treatment
  4. Target

    Probable arabinosyltransferase A

    go.drugbank.com/bio_entities/BE0000034
    TargetMycobacterium tuberculosis

    Arabinosyl transferase responsible for the polymerization of arabinose into the arabinan of arabinogalactan.

    Polypeptides: Probable arabinosyltransferase A
  5. Target

    Aurora kinase A

    go.drugbank.com/bio_entities/BE0000991
    TargetHumans

    Plays a role in microtubule remodeling during neurite extension (PubMed:19668197). … Associates with the centrosome and the spindle microtubules during mitosis and plays a critical role in various mitotic events including the establishment of mitotic spindle, centrosome duplication, centrosome

    Polypeptides: Aurora kinase ASynonyms: Serine/threonine-protein kinase aurora-A
  6. Target

    Bacteriochlorophyll a protein

    go.drugbank.com/bio_entities/BE0001362
    TargetChlorobium tepidum (strain ATCC 49652 / DSM 12025 / TLS)

    Intermediary in the transfer of excitation energy from the chlorophyll to the reaction centers.

    Polypeptides: Bacteriochlorophyll a protein
  7. Target

    Beta-glucosidase A

    go.drugbank.com/bio_entities/BE0001810
    TargetEnzymeThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)

    Polypeptides: Beta-glucosidase A
  8. Target

    Complement C4-A

    go.drugbank.com/bio_entities/BE0004685
    TargetHumans

    Precursor of non-enzymatic components of the classical, lectin and GZMK complement pathways, which consist in a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that

    Polypeptides: Complement C4-A
  9. Target

    Pepsin A-5

    go.drugbank.com/bio_entities/BE0009737
    TargetHumans

    Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent

    Polypeptides: Pepsin A-5
  10. Target

    Pepsin A-4

    go.drugbank.com/bio_entities/BE0012524
    TargetHumans

    Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent

    Polypeptides: Pepsin A-4