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Displaying results 1071 - 1080 of 10000 in total
  1. Drug

    Methadone

    go.drugbank.com/drugs/DB00333
    ApprovedInvestigational

    At higher doses, methadone use can result in respiratory depression, overdose, and death. … [A185882] Illegally purchased opioids present many other harms in addition to overdose as they can be injected and may be laced with other substances that increase the risk of harm or overdose.

    Categories: Drugs Used in Opioid Dependence, Drugs Used in Addictive DisordersProducts: Alphadone Syrup 10mg/ml, METADONA SOLUCIÓN ORAL 10MG/ML
  2. Drug

    Nalbuphine

    go.drugbank.com/drugs/DB00844
    ApprovedInvestigational

    It appears to be an agonist at kappa opioid receptors and an antagonist or partial agonist at mu opioid receptors. … Nalbuphine is the only opioid analgesic that is not a controlled substance in the United States.

    Synonyms: N-cyclobutylmethyl-4,5α-epoxy-3,6α,14-morphinantriolProducts: Nubain Injection 10mg/ml, Nubain Injection 20mg/ml
  3. Pathway

    Metabolism and Physiological Effects of N-alpha-Acetyl-L-arginine

    smpdb.ca/view/SMP0125530
    Metabolic

    N-Acetylarginine can also be classified as an alpha amino acid or a derivatized alpha amino acid. … Uremic toxins are a diverse group of endogenously produced molecules that, if not properly cleared or eliminated by the kidneys, can cause kidney damage, cardiovascular disease and neurological deficits

    Drugs: Pyridoxal phosphate · Arginine · Aspartic acid · Ornithine · L-Glutamine · Adenosine phosphate +10 more
  4. Pathway

    Ziconotide NMDA and Substance P Receptor Pain Inhibition Action Pathway

    smpdb.ca/view/SMP0126347
    Drug action

    Nociceptive pain signalling is a complex processing pathway involving peripheral nociceptors, primary afferent nerve fibres, and downstream CNS neurons located in the spinal cord such as the dorsal root … Ziconotide inhibits Voltage-dependent N-type calcium channels in presynaptic neurons.

    Drugs: Glutamic acid · Calcium · Sar9, Met (O2)11-Substance P · Ziconotide
  5. Drug

    Gadobenic acid

    go.drugbank.com/drugs/DB00743
    ApprovedInvestigational

    [A263166] As gadobenate dimeglumine is specifically taken up by hepatocytes and excreted through the biliary system, it is a useful contrast agent for liver MRI. … [A263086] It differs from other GBCAs due to the benzene ring that confers weak protein binding, thus leading to an increased R1 and R2 relaxivity.

    Categories: Compounds used in a research, industrial, or household settingProducts: MultiHance 0,5 mmol/ml Injektionslösung in einer Fertigspritze, MULTIHANCE TEK DOZLUK IV ENJEKSIYONLUK COZELTI ICEREN FLAKON, 5 ML
  6. Drug

    Glipizide

    go.drugbank.com/drugs/DB01067
    ApprovedInvestigational

    [A179485] Glipizide was first approved by the FDA in 1994 and is available in extended-release tablets under the brand name Glucotrol®, as well as in combination with metformin under the brand name Metaglip … Glipizide is an oral hypoglycemic agent in the second-generation sulfonylurea drug class that is used to control blood sugar levels in patients with type 2 diabetes mellitus.

    Mixtures: Glipizide and Metformin HCl, Glipizide and Metformin HClCategories: Drugs Used in Diabetes, Alimentary Tract and Metabolism
  7. Drug

    Lanthanum carbonate

    go.drugbank.com/drugs/DB06792
    Approved

    It is used to treat elevated phosphate levels, primarily in patients with chronic kidney disease, by binding to dietary phosphate and preventing its absorption in the intestine.[L50733] … It is a large pill that requires thorough chewing to avoid choking and other gastrointestinal adverse effects.

    Categories: Drugs for Treatment of Hyperkalemia and HyperphosphatemiaProducts: FOSRENOL CHEWABLE TABLETS 500MG, Fosrenol Chewable Tablets 500mg
  8. Drug

    Sodium chloride

    go.drugbank.com/drugs/DB09153
    ApprovedInvestigationalVet approved

    Sodium chloride, also known as salt, common salt, table salt or halite, is an ionic compound with the chemical formula NaCl, representing a 1:1 ratio of sodium and chloride ions. … Sodium chloride is the primary salt in seawater and in the extracellular fluid of many multicellular organisms. It is listed on the World Health Organization Model List of Essential Medicines.

    Mixtures: P-Care 100MX, Mencevax Ac Pws 50mcg/vialCategories: Alimentary Tract and Metabolism, Blood and Blood Forming Organs
  9. Drug

    Tenofovir disoproxil

    go.drugbank.com/drugs/DB00300
    ApprovedInvestigational

    This drug is prescribed in combination with other drugs for the management of HIV infection as well as for Hepatitis B therapy. Tenofovir disoproxil was initially approved in 2001 [FDA label]. … Tenofovir disoproxil fumarate (a prodrug of tenofovir), marketed by Gilead Sciences under the trade name _Viread_, belongs to a class of antiretroviral drugs known as nucleotide analogue reverse transcriptase

    Mixtures: STRIBILD 150MG/150MG/200MG/245MG FILM KAPLI TABLET, 90 ADET, STRIBILD 150MG/150MG/200MG/245MG FILM KAPLI TABLET, 30 ADETCategories: Antivirals used in combination for the treatment of HIV infections, Tenofovir and prodrugs
  10. Drug

    Cysteine

    go.drugbank.com/drugs/DB00151
    ApprovedInvestigationalNutraceutical

    A thiol-containing non-essential amino acid that is oxidized to form cystine.

    Mixtures: PF K-CAMINE %8 AMINO ASIT IV INFUZYON ICIN COZELTI, 1000 ML (SETLI), PF K-CAMINE %8 AMINO ASIT IV INFUZYON ICIN COZELTI, 1000 ML (SETSIZ)Categories: Amino Acids, Peptides, and Proteins