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Displaying results 1071 - 1080 of 10000 in total
  1. Drug

    Carboxymethylcellulose

    go.drugbank.com/drugs/DB11059
    ApprovedInvestigational

    It is added in food products as a viscosity modifier or thickener and emulsifier. … Carboxymethylcellulose is a cellulose derivative that consists of the cellulose backbone made up of glucopyranose monomers and their hydroxyl groups bound to carboxymethyl groups.

    Mixtures: OPTIVE ®, OPTIVE ®Categories: Compounds used in a research, industrial, or household setting
  2. Drug

    Cinnamon oil

    go.drugbank.com/drugs/DB15986
    ApprovedInvestigational

    Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 CYP2C9 InhibitorsProducts: Nwk A-FV
  3. Drug

    Pemetrexed

    go.drugbank.com/drugs/DB00642
    ApprovedInvestigational

    Pemetrexed is a chemotherapy drug that is manufactured and marketed by Eli Lilly and Company under the brand name Alimta. … Its use in non-small cell lung cancer has also been investigated. Pemetrexed was first approved by the FDA in February 4, 2004.[A253907]

    Categories: OAT3/SLC22A8 Substrates with a Narrow Therapeutic Index, Drugs that are Mainly Renally Excreted with a Narrow Therapeutic IndexProducts: NEXTREXED 500 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE, PEMETREXED MASTERS® 500 MG POLVO LIOFILIZADO ESTÉRIL PARA RECONSTITUIR A SOLUCION INYECTABLE.
  4. Target

    L-lactate dehydrogenase A-like 6B

    go.drugbank.com/bio_entities/BE0000100
    TargetHumans

    Catalyzes the interconversion of L-lactate and pyruvate with nicotinamide adenine dinucleotide NAD(+) as a coenzyme

    Polypeptides: L-lactate dehydrogenase A-like 6B
  5. Target

    Serine/threonine-protein kinase A-Raf

    go.drugbank.com/bio_entities/BE0000434
    TargetHumans

    Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May also regulate the TOR signaling cascade. Phosphorylates PFKFB2 (PubMed:36402789)

    Polypeptides: Serine/threonine-protein kinase A-RafSynonyms: Proto-oncogene A-Raf, Proto-oncogene A-Raf-1
  6. Target

    Coenzyme A biosynthesis bifunctional protein CoaBC

    go.drugbank.com/bio_entities/BE0002020
    TargetEscherichia coli (strain K12)

    Catalyzes two sequential steps in the biosynthesis of coenzyme A.

    Polypeptides: Coenzyme A biosynthesis bifunctional protein CoaBC
  7. Target

    Chain A, Red Copper Protein Nitrosocyanin

    go.drugbank.com/bio_entities/BE0002711
    TargetNitrosomonas europaea (strain ATCC 19718 / NBRC 14298)

    Polypeptides: Chain A, Red Copper Protein Nitrosocyanin
  8. Target

    Peptidyl-prolyl cis-trans isomerase A

    go.drugbank.com/bio_entities/BE0004194
    TargetEscherichia coli (strain K12)

    PPIases accelerate the folding of proteins (Probable). It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (PubMed:2190212).

    Polypeptides: Peptidyl-prolyl cis-trans isomerase ASynonyms: PPIase A, Rotamase A
  9. Target

    Platelet-derived growth factor subunit A

    go.drugbank.com/bio_entities/BE0010246
    TargetHumans

    Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal lung alveolar septum ...

    Polypeptides: Platelet-derived growth factor subunit ASynonyms: PDGF subunit A, Platelet-derived growth factor A chain
  10. Target

    Esterase EstA

    go.drugbank.com/bio_entities/BE0003982
    TargetPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)

    In vitro, has pronounced esterase activities towards p-nitrophenyl esters of short acyl chain length (C4-C6) and Tween detergents. … Esterase whose enzymatic activity is required for rhamnolipid production, all kinds of cell motility (swimming, swarming, and twitching), and biofilm formation; the exact role of EstA in these processes

    Polypeptides: Esterase EstASynonyms: Autotransporter esterase EstA