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Displaying results 1071 - 1080 of 10000 in total
  1. Drug

    Umeclidinium

    go.drugbank.com/drugs/DB09076
    ApprovedInvestigational

    COPD is a progressive obstructive lung disease characterized by shortness of breath, cough, sputum production, and chronically poor airflow with a forced expiratory volume in 1 second (FEV1) of less than … [A7719] However, even though umeclidinium monotherapy is well-tolerated for up to 14 days, it is more likely to be used in combination therapy, as the international Gold Initiative for Chronic Obstructive

    Mixtures: TRELEGY ELLİPTA 100 MCG + 62,5 MCG +25 MCG KULLANIMA HAZIR İNHALASYON TOZU, 30 DOZ, TRELEGY ELLIPTA INHALATION POWDER 100 MCG/62.5 MCG/25 MCGCategories: Drugs for Obstructive Airway Diseases
  2. Drug

    Dextran

    go.drugbank.com/drugs/DB09255
    ApprovedInvestigationalVet approved

    [T121] Dextran 40 is a sterile, nonpyrogenic preparation of low molecular weight dextran (average mol. wt. 40,000) in 5% Dextrose Injection or 0.9% Sodium Chloride Injection. … Dextran is a polysaccharide that differs from others in that its glucose units are joined together 1:6 glucoside links.

    Salts: Dextran 40, Dextran 70Mixtures: Visine for Red Eye Cool, Visine for Red Eye Workplace
  3. Drug

    Molsidomine

    go.drugbank.com/drugs/DB09282
    ApprovedWithdrawn

    Interestingly, it is being studied as being a preventive measure in cerebral infarction [A31932].

    Categories: Heterocyclic Compounds, 1-RingProducts: Nesidom 16 mg - Retardtabletten, MOLSIDOMIN 8 RET 1A PHARMA
  4. Drug

    Fluvastatin

    go.drugbank.com/drugs/DB01095
    ApprovedInvestigational

    Fluvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. … HMG-CoA reductase catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting step in cholesterol biosynthesis.

    Categories: Hypolipidemic Agents Indicated for HyperlipidemiaProducts: FLUVASTATIN 1A PH 80MG RET, Lescol MR 80 mg - Filmtabletten
  5. Drug

    Desipramine

    go.drugbank.com/drugs/DB01151
    Approved

    See toxicity section below for a complete listing of side effects. … TCAs also block histamine-H<sub>1</sub> receptors, &alpha;<sub>1</sub>-adrenergic receptors and muscarinic receptors, which accounts for their sedative, hypotensive and anticholinergic effects (e.g. blurred

    Categories: Antidepressive Agents Indicated for Depression, Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic IndexProducts: DESIPRAM 25 MG TABLET, 100 ADET, Desipramine-10 - Tab 10mg
  6. Drug

    Tafluprost

    go.drugbank.com/drugs/DB08819
    Approved

    Chemically, tafluprost is a fluorinated analog of prostaglandin F2-alpha. Tafluprost was approved for use in the U.S. on February 10, 2012. … A prostaglandin analogue ester prodrug used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension.

    Mixtures: Taptiqom 15 Mikrogramm/ml + 5 mg/ml Augentropfen, Lösung im Einzeldosisbehältnis, TAPCOM-S ophthalmic solution 15 micrograms/ml + 5 mg/ml, solution in single-dose containerProducts: SAFLUTAN 15 MCG/ML TEK DOZLUK GOZ DAMLASI, 30 ADET, Saflutan 15 Mikrogramm/ml Augentropfen, Lösung
  7. Target

    NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial

    go.drugbank.com/bio_entities/BE0000081
    TargetHumans

    Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The ...

    Polypeptides: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial
  8. Target

    Solute carrier family 2, facilitated glucose transporter member 10

    go.drugbank.com/bio_entities/BE0005220
    TransporterHumans

    Facilitative glucose transporter required for the development of the cardiovascular system

    Polypeptides: Solute carrier family 2, facilitated glucose transporter member 10Synonyms: GLUT-10, Glucose transporter type 10
  9. Drug

    Ofatumumab

    go.drugbank.com/drugs/DB06650
    ApprovedInvestigational

    [L12753] The FDA subsequently approved ofatumumab for the treatment of RMS on August 20, 2020. … [L12612] Although it has a similar molecular mechanism of action as [rituximab], another CD-20 monoclonal antibody used in the treatment of rheumatoid arthritis and B-cell non-Hodgkin's lymphoma, ofatumumab

    Categories: CD20 (Clusters of Differentiation 20) inhibitorsProducts: Jemvy 20 mg/0,4 mL Enjeksiyonluk Çözelti İçeren Kullanıma Hazır Kalem, 1 ADET, JEMVY 20 MG/0,4 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET
  10. Drug

    Medronic acid

    go.drugbank.com/drugs/DB14078
    ApprovedInvestigational

    Products: MON MDP KIT 10 MG IV ENJEKSİYON İÇİN LİYOFİLİZE TOZ İÇEREN FLAKON, 5 ADET