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Oxibendazole
go.drugbank.com/drugs/DB04910ExperimentalVet approvedOxibendazole is a polymerase inhibitor in phase III trials for the treatment of helminth intestinal infections.
Categories: Heterocyclic Compounds, 2-RingSynonyms: Methyl 5-n-propoxy-2-benzimidazole carbamate, Methyl 5-propoxy-2-benzimidazolecarbamateBufotenine
go.drugbank.com/drugs/DB01445ExperimentalIllicitBufotenin has been used as a tool in CNS studies and misused as a psychedelic. … A hallucinogenic serotonin analog found in frog or toad skins, mushrooms, higher plants, and mammals, especially in the brains, plasma, and urine of schizophrenics.
Categories: Heterocyclic Compounds, 2-Ring, Serotonin 5-HT1 Receptor AntagonistsSynonyms: 3-[2-(dimethylamino)ethyl]-5-indolol, 3-[2-(dimethylamino)ethyl]indol-5-olAlbuterol
go.drugbank.com/drugs/DB01001ApprovedInvestigationalVet approvedIt is 29 times more selective for beta2 receptors than beta1 receptors giving it higher specificity for pulmonary beta receptors versus beta1-adrenergic receptors located in the heart. … The R-isomer has 150 times greater affinity for the beta2-receptor than the S-isomer and the S-isomer has been associated with toxicity.
Mixtures: PRALAS 2,5 MG+0,5 MG/2,5 ML NEBÜLİZASYON ÇÖZELTİSİ, 20 ADET, PRALAS 100 MCG/20 MCG İNHALASYON İÇİN ÇÖZELTİ İÇEREN ÖLÇÜLÜ DOZLU AEROSOL, 1 ADETCategories: Adrenergic beta-2 Receptor Agonists, Selective Beta 2-adrenergic AgonistsLevocetirizine
go.drugbank.com/drugs/DB06282ApprovedInvestigationalLevocetirizine is a selective histamine H<sub>1</sub> antagonist used to treat a variety of allergic symptoms.[A181748,A181790,L7694] It is the R enantiomer of [cetirizine]. … [L7694] Levocetirizine has greater affinity for the histamine H<sub>1</sub> receptor than cetirizine.[L7694] Levocetirizine was granted FDA approval in 1995.[L7694]
Mixtures: LEVDAY PLUS 2,5 MG/120 MG EFERVESAN TABLET, 20 ADET, BROCRIPTIN® 10 MG/ 5 MGCategories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 SubstratesEniluracil
go.drugbank.com/drugs/DB03516InvestigationalEniluracil could improve 5-FU by increasing its effectiveness, reducing its side effects and/or making it orally available. … Eniluracil, which was previously under development by GlaxoSmithKline (GSK), is being developed by Adherex to enhance the therapeutic value and effectiveness of 5-fluorouracil (5-FU), one of the world’
Categories: Heterocyclic Compounds, 1-RingSynonyms: 5-EthynyluracilWNT-974
go.drugbank.com/drugs/DB12561InvestigationalWNT974 has been used in trials studying the treatment of Metastatic Colorectal Cancer and Squamous Cell Carcinoma, Head And Neck.
Synonyms: (2,4'-bipyridine)-5-acetamide, 2',3-dimethyl-N-(5-(2-pyrazinyl)-2-pyridinyl)-Categories: Heterocyclic Compounds, 1-RingHUB-101
go.drugbank.com/drugs/DB18656ExperimentalSynonyms: Adeno-associated viral 2/5 (AAV2/5) vector expressing the human KCNJ13 geneCyclic adenosine monophosphate
go.drugbank.com/drugs/DB02527InvestigationalCyclic adenosine monophosphate (cAMP, cyclic AMP or 3'-5'-cyclic adenosine monophosphate) is a molecule that is important in many biological processes; it is derived from adenosine triphosphate (ATP).
Categories: Heterocyclic Compounds, 2-RingSynonyms: 3',5'-cyclic AMP, Adenosine 3',5'-phosphateMetoprolol
go.drugbank.com/drugs/DB00264ApprovedInvestigationalMetoprolol is a selective beta-1 blocker commonly employed as the succinate and tartrate derivatives depending if the formulation is designed to be of immediate release or extended release. … [T274] To this date, it is one of the preferred beta-blockers in general clinical guidelines and it is widely prescribed in the Netherlands, New Zealand, and the US.
Mixtures: Implicor 50 mg/5 mg Filmtabletten, IMPLICOR FILM-COATED TABLET 50 mg/5 mgCategories: Adrenergic beta-1 Receptor Antagonists, Cytochrome P-450 Substrates1-[5-Methyl-2-(trifluoromethyl)furan-3-yl]-3-[5-[2-[[6-(1H-1,2,4-triazol-5-ylamino)pyrimidin-4-yl]amino]ethyl]-1,3-thiazol-2-yl]urea
go.drugbank.com/drugs/DB07789ExperimentalSynonyms: 1-[5-Methyl-2-(trifluoromethyl)furan-3-yl]-3-[5-[2-[[6-(1H-1,2,4-triazol-5-ylamino)pyrimidin-4-yl]amino]ethyl]-1,3-thiazol-2-yl]urea