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Fluvastatin
go.drugbank.com/drugs/DB01095ApprovedInvestigationalHMG-CoA reductase catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting step in cholesterol biosynthesis. … Fluvastatin belongs to a class of medications called statins and is used to reduce plasma cholesterol levels and prevent cardiovascular disease.
Categories: Cytochrome P-450 CYP2B6 Inducers, Cytochrome P-450 CYP1A1 SubstratesProducts: LESCOL XL TABLET 80 mg, FLUVASTATIN HOLSTEN 80 MGPrednisolone acetate
go.drugbank.com/drugs/DB15566ApprovedInvestigationalVet approvedPrednisolone acetate is a [prednisolone] molecule bound to an acetate functional group by an ester bond.[L9449] Prednisolone acetate was granted FDA approval in 1955.[L9449]
Mixtures: BLEPHAMIDE % 0,2 + % 10 GÖZ DAMLASI, SÜSPANSİYON, 5 ML, SUPRENIL STERIL OFTALMIK SUSPANSIYON 5 MLCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersPapain
go.drugbank.com/drugs/DB11193ApprovedWithdrawnWhile it has been used for the treatment of inflammation and pain via topical administration, papain has also shown to have anthelmintic and tooth-whitening properties. … The enzyme is found to be localized in the skin of papaya, and is collected from slashed unripe papayas as a crude latex. Papain is used in food, pharmaceutical, textile, and cosmetic industries.
Mixtures: Herbalax Forte No 70 Tab, NATURE'S BOUNTY NATUREL B-COMPLEX AND B-12 TABLET, 90 ADETProducts: Papaya Enzyme - Tablet 30 mg, NORIPAPAIN 10 000 USP UNITS TABLETPivampicillin
go.drugbank.com/drugs/DB01604ApprovedWithdrawnPivalate ester analog of ampicillin.
Categories: Penicillin GProducts: PIVACIL KAPSUL 350 MG, 16 ADET, PIVACIL KAPSUL 350 MG, 1000 ADETAvelumab
go.drugbank.com/drugs/DB11945ApprovedInvestigationalAvelumab is a human IgG1 lambda monoclonal antibody that binds programmed cell death ligand-1 (PD-L1) to block its interaction with its receptors found on T cells and antigen-presenting cells. … [A261496] Avelumab was first approved by the FDA on March 23, 2017.
Products: BAVENCIO 200 MG/10 ML IV İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 FLAKON, BAVENCIO 200 mg/10mL concentrate for solution for infusionRitodrine
go.drugbank.com/drugs/DB00867ApprovedWithdrawnAdrenergic beta-agonist used to control premature labor.
Products: PRE-PAR 50 MG/5 ML IM/IV ÇÖZELTİ İÇEREN AMPUL, 1 AMPULThyrotropin alfa
go.drugbank.com/drugs/DB00024ApprovedInvestigationalVet approvedThe beta subunit (TSHB) bestows its receptor specificity due to the uniqueness to TSH. The amino acid sequence of thyrotropin alfa is identical to that of human pituitary thyroid stimulating hormone. … It is also used along with a radioactive agent to destroy remaining thyroid tissue in certain patients who have had their thyroid gland removed because of thyroid cancer.
Categories: Agents used to treat hypothyroidismProducts: THYROGEN 0,9 MG/1,08 ML IM ENJEKSİYONLUK ÇÖZELTİ İÇİN TOZ İÇEREN FLAKON, 2 FLAKON, Thyrogen 0.9 mg Powder for Solution for InjectionSufentanil
go.drugbank.com/drugs/DB00708ApprovedInvestigationalThis route of administration is intended to be a simple, effective, non-invasive analgesic option to enable healthcare professionals to rapidly manage acute pain without difficult intravenous or epidural … It is administered by the intravenous, epidural and sublingual routes.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Cytochrome P-450 SubstratesProducts: Sufentanil-hameln 10 Mikrogramm/ml Injektions-/Infusionslösung, Sufentanil Panpharma 50 Mikrogramm/ml InjektionslösungAprotinin
go.drugbank.com/drugs/DB06692ApprovedInvestigationalWithdrawnFor this use, it is typically administered by injection. … The goal of using of aprotinin was subsequently to minimize end-organ damage resulting from hypotension due to blood loss in surgery and to reduce the necessity for blood transfusions during surgery.
Mixtures: ARTISS 10 ML ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTOR, 1 ADET, TISSEEL 10 ML ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR 1 ADETProducts: Trasylol 10 000 KIE/ml Infusionslösung, TRASYLOL INJECTION 500,000 kiu/50 mlRanolazine
go.drugbank.com/drugs/DB00243ApprovedInvestigational[L3580] With a mechanism of action different from drugs used to treat the same condition, ranolazine is a promising anti-anginal therapy. It was originally approved by the FDA in 2006.[L5440]
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 InhibitorsProducts: RAZİNA 1000 MG UZATILMIŞ SALIMLI TABLET, 60 ADET, RAZİNA 500 MG UZATILMIŞ SALIMLI TABLET, 60 ADET