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Displaying results 101 - 110 of 561 in total
  1. Target

    Protein-tyrosine kinase 2-beta

    go.drugbank.com/bio_entities/BE0000871
    TargetHumans

    Non-receptor protein-tyrosine kinase that regulates reorganization of the actin cytoskeleton, cell polarization, cell migration, adhesion, spreading and bone remodeling. Plays a role in the regulation of the humoral immune response, and ...

    Synonyms: Calcium-dependent tyrosine kinase, Calcium-regulated non-receptor proline-rich tyrosine kinase
  2. Target

    P-type Ca(2+) transporter

    go.drugbank.com/bio_entities/BE0009164
    TargetPlasmodium falciparum

    Synonyms: P-type calcium transporting ATPase
  3. Target

    Calpain-1 catalytic subunit

    go.drugbank.com/bio_entities/BE0003346
    TargetHumans

    Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction (PubMed:19617626, PubMed:21531719, PubMed:2400579

    Synonyms: Calcium-activated neutral proteinase 1Function: calcium ion binding
  4. Target

    Calpain-2 catalytic subunit

    go.drugbank.com/bio_entities/BE0012693
    TargetHumans

    Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.

    Synonyms: Calcium-activated neutral proteinase 2Function: calcium ion binding
  5. Target

    Ryanodine receptor 1

    go.drugbank.com/bio_entities/BE0000739
    TargetTransporterHumans

    Cytosolic calcium-activated calcium channel that mediates the release of Ca(2+) from the sarcoplasmic reticulum into the cytosol and thereby plays a key role in triggering muscle contraction following

    Synonyms: Skeletal muscle calcium release channel
  6. Target

    Protein S100-A10

    go.drugbank.com/bio_entities/BE0009033
    TargetHumans

    Because S100A10 induces the dimerization of ANXA2/p36, it may function as a regulator of protein phosphorylation in that the ANXA2 monomer is the preferred target (in vitro) of tyrosine-specific kinase

    Synonyms: S100 calcium-binding protein A10Function: calcium ion binding
  7. Target

    Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial

    go.drugbank.com/bio_entities/BE0000277
    TargetHumans

    Mitochondrial electrogenic aspartate/glutamate antiporter that favors efflux of aspartate and entry of glutamate and proton within the mitochondria as part of the malate-aspartate shuttle (PubMed:11566871, PubMed:38937634, PubMed:3894528...

    Synonyms: Calcium-binding mitochondrial carrier protein Aralar2
  8. Target

    PcrV

    go.drugbank.com/bio_entities/BE0002380
    TargetPseudomonas aeruginosa

    Synonyms: Low calcium response locus protein V
  9. Target

    Protein S100-A9

    go.drugbank.com/bio_entities/BE0008993
    TargetHumans

    S100A9 is a calcium- and zinc-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response (PubMed:12626582, PubMed:15331440, PubMed:16258195, PubMed:19122197

    Synonyms: S100 calcium-binding protein A9
  10. Target

    Phosphodiesterase enzymes

    go.drugbank.com/bio_entities/BE0009789
    TargetHumans

    Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes

    Polypeptides: Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B