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Indomethacin Action Pathway
smpdb.ca/view/SMP0000104Drug actionProstaglandin G/H synthase 1 and 2 catalyze the arachidonic acid to prostaglandin G2, and also catalyze prostaglandin G2 to prostaglandin H2 in the metabolism pathway. … It can be used to treat prostaglandin G/H synthase related fever, swelling, pain and inflammation.
Drugs: Glutamic acid · Glutathione · Indomethacin · Dinoprostone · Calcium · Magnesium cation +5 moreNabumetone Action Pathway
smpdb.ca/view/SMP0000114Drug actionNabumetone (also named Relafen and Relifex) is a nonsteroidal anti-inflammatory drug (NSAID). It can be used to relieve pain (analgesic) and reduce fever (antipyretic). … Prostaglandin G/H synthase 1 and 2 catalyze the arachidonic acid to prostaglandin G2, and also catalyze prostaglandin G2 to prostaglandin H2 in the metabolism pathway.
Antipyrine Action Pathway
smpdb.ca/view/SMP0000692Drug actionProstaglandin G/H synthase 1 and 2 catalyze the arachidonic acid to prostaglandin G2, and also catalyze prostaglandin G2 to prostaglandin H2 in the metabolism pathway. … Antipyrine can block prostaglandin synthesis by the action of inhibition of prostaglandin G/H synthase 1 and 2.
Antrafenine Action Pathway
smpdb.ca/view/SMP0000693Drug actionProstaglandin G/H synthase 1 and 2 catalyze the arachidonic acid to prostaglandin G2, and also catalyze prostaglandin G2 to prostaglandin H2 in the metabolism pathway. … Antrafenine can block prostaglandin synthesis by the action of inhibition of prostaglandin G/H synthase 1 and 2.
Drugs: Glutamic acid · Glutathione · Dinoprostone · Calcium · Magnesium cation · Antrafenine +5 moreCarprofen Action Pathway
smpdb.ca/view/SMP0000694Drug actionProstaglandin G/H synthase 1 and 2 catalyze the arachidonic acid to prostaglandin G2, and also catalyze prostaglandin G2 to prostaglandin H2 in the metabolism pathway. … Carprofen can block prostaglandin synthesis by the action of inhibition of prostaglandin G/H synthase 1 and 2.
Lumiracoxib Action Pathway
smpdb.ca/view/SMP0000699Drug actionProstaglandin G/H synthase 1 and 2 catalyze the arachidonic acid to prostaglandin G2, and also catalyze prostaglandin G2 to prostaglandin H2 in the metabolism pathway. … Lumiracoxib can block prostaglandin synthesis by the action of inhibition of prostaglandin G/H synthase 1 and 2.
Drugs: Glutamic acid · Glutathione · Dinoprostone · Lumiracoxib · Calcium · Magnesium cation +5 morePhosphatidylinositol Phosphate Metabolism
smpdb.ca/view/SMP0000463MetabolicThe specific localization and regulation of the phosphoinositide kinases and phosphatases thus controls the activity of the phosphoinositides. … Conversion between the different types of phosphoinositides is then done by a number of specific phosphoinositide kinases and phosphatases, which add (kinase) and remove (phosphatase) phosphates from the
Enzymes: Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTENSimeprevir Action Pathway
smpdb.ca/view/SMP0125950Drug actionThe lipoviroparticles attach to LDL-R and SR-B1, and then the virus binds to CD81 and subsequently claudin-1 and occludin, which mediate the late steps of viral entry. … , and NS5B.
Voxilaprevir Action Pathway
smpdb.ca/view/SMP0125962Drug actionThe lipoviroparticles attach to LDL-R and SR-B1, and then the virus binds to CD81 and subsequently claudin-1 and occludin, which mediate the late steps of viral entry. … NS5A, and NS5B.
Gemcitabine Action Pathway (old)
smpdb.ca/view/SMP0000446Drug actionGemcitabine is phosphorylated into gemcitabine monophosphate by deoxycytidine kinase, which is then subsequently phosphorylated into the diphosphate and triphosphate nucleotides by UMP-CMP kinase and nucleoside … Gemcitabine enters the cell via sodium nucleoside co-transporters (SLC29A1, SLC28A1, and SLC28A3), where it acts through multiple mechanisms to produce a cytotoxic effect.