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Zinc transporter ZIP2
go.drugbank.com/bio_entities/BE0009889TransporterHumansThe Zn(2+) uniporter activity is independent of H(+)-driving force, but is modulated by extracellular pH and membrane potential.
Synonyms: Zrt- and Irt-like protein 2Pulmonary surfactant-associated protein A1
go.drugbank.com/bio_entities/BE0004481TargetHumansIn presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal
Polypeptides: Pulmonary surfactant-associated protein A1Synonyms: 35 kDa pulmonary surfactant-associated proteinPulmonary surfactant-associated protein A2
go.drugbank.com/bio_entities/BE0016550TargetHumansIn presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal
Polypeptides: Pulmonary surfactant-associated protein A2Synonyms: 35 kDa pulmonary surfactant-associated proteinPulmonary surfactant-associated protein D
go.drugbank.com/bio_entities/BE0001107TargetHumansMay participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties … Interacts with compounds such as bacterial lipopolysaccharides, oligosaccharides and fatty acids and modulates leukocyte action in immune response.
Polypeptides: Pulmonary surfactant-associated protein DPulmonary surfactant-associated protein B
go.drugbank.com/bio_entities/BE0012543TargetHumansPulmonary surfactant-associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces.
Polypeptides: Pulmonary surfactant-associated protein BSynonyms: 18 kDa pulmonary-surfactant protein, Pulmonary surfactant-associated proteolipid SPL(Phe)3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2
go.drugbank.com/bio_entities/BE0000059TargetEnzymeHumans3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids.
Synonyms: 3-beta-HSD adrenal and gonadal typeP-type Ca(2+) transporter
go.drugbank.com/bio_entities/BE0009164TargetPlasmodium falciparumSynonyms: Sarcoplasmic and endoplasmic reticulum Ca-ATPaseZinc transporter ZIP6
go.drugbank.com/bio_entities/BE0009887TransporterTargetHumansThe SLC39A10-SLC39A6 heterodimer also controls NCAM1 phosphorylation and its integration into focal adhesion complexes during EMT (By similarity). … Zinc-influx transporter which plays a role in zinc homeostasis and in the induction of epithelial-to-mesenchymal transition (EMT) (PubMed:12839489, PubMed:18272141, PubMed:21422171, PubMed:23919497, PubMed
Synonyms: Zrt- and Irt-like protein 6Thioredoxin reductase
go.drugbank.com/bio_entities/BE0010144TargetMousePromotes disulfide bond formation between GPX4 and various sperm proteins and may play a role in sperm maturation by promoting formation of sperm structural components. … Homodimeric flavoprotein involved in the regulation of cellular redox reactions, growth and differentiation.
Synonyms: Thioredoxin and glutathione reductaseStabilin-1
go.drugbank.com/bio_entities/BE0010944TargetHumansBinds to both Gram-positive and Gram-negative bacteria and may play a role in defense against bacterial infection.
Synonyms: Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 1