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Methylnaltrexone
go.drugbank.com/drugs/DB06800ApprovedInvestigationalMethylnaltrexone is a pheriphally-acting μ-opioid antagonist that acts on the gastrointestinal tract to decrease opioid-induced constipation without producing analgesic effects or withdrawal symptoms. … It is also a weak CYP2D6 inhibitor. FDA approved in 2008.
Categories: Drugs for Constipation, Heterocyclic Compounds with 4 or More RingsProducts: RELISTOR (TM) (SUBCUTANEOUS INJECTION,12MG/0.6ML PER VIAL), Relistor Solution For Injection 12mg/0.6mLEravacycline
go.drugbank.com/drugs/DB12329ApprovedInvestigationalEravacycline has demonstrated superior potency to that of antibiotics that are currently being marketed for intraabdominal infections [A38727]. … Eravacycline, known as _Xerava_ by Tetraphase Pharmaceuticals, is a fully synthetic fluorocycline antibiotic of the tetracycline class with activity against clinically significant gram-negative, gram-positive
Categories: Monoamine Oxidase A Substrates, Antibacterials for Systemic UseProducts: XERAVA POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 50MG PER VIALTimolol
go.drugbank.com/drugs/DB00373ApprovedInvestigationalTimolol is a nonselective beta-adrenergic antagonist given in an eye drop solution to reduce intraocular pressure, or pressure in the eyes. … [L6724] It is also used in tablet form as a drug to treat hypertension.[L6727] Timolol was first approved by the FDA in 1978.
Mixtures: Tim-Dor-Lat, Tim-Brim-Dor-LatProducts: TIMOLOL-POS 0.5% EYE DROPS, TIMOLOL-POS EYE DROPS 0.5%Colloidal oatmeal
go.drugbank.com/drugs/DB11286ApprovedNutraceuticalColloidal oatmeal is a FDA-approved skin protectant that temporarily protects and helps relieve minor skin irritation and itching due to rashes, eczema, poison ivy, oak, sumac, or insect bites. … It is available in topical products as a skin soothing agent.
Products: La Roche Posay Laboratoire Dermatologique Lipikar Eczema Relief, La Roche Posay Laboratoire Dermatologique Lipikar Eczema Soothing ReliefCalcitriol
go.drugbank.com/drugs/DB00136ApprovedInvestigationalNutraceuticalCalcitriol is marketed under various trade names including Rocaltrol (Roche), Calcijex (Abbott) and Decostriol (Mibe, Jesalis). … It is also available in topical form for the treatment of mild to moderate plaque psoriasis in adults.
Categories: Antipsoriatics for Topical UseProducts: CITRIOPOR CAPSULAS POR 0.25 MCG, K-LAMXylose
go.drugbank.com/drugs/DB09419ApprovedWithdrawnThe levorotary form, L-xylose, can refer to the form that is synthesized. … D-Xylose is a sugar widely used as a diabetic sweetener in food and beverage. Xylose has also been used as a diagnostic agent to observe malabsorption.
Products: Xylo-tol Pwr 25gm/pckCilastatin
go.drugbank.com/drugs/DB01597ApprovedInvestigational[L7628] A newer triple-drug product was approved in July 2019 under the trade name Recarbrio which also contains [relebactam].[L4894] … Cilastatin is an inhibitor of renal dehydropeptidase, an enzyme responsible for both the metabolism of thienamycin beta-lactam antibiotics as well as conversion of leukotriene D4 to leukotriene E4.
Mixtures: IMIPENEM/CILASTATINA POLVO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE, ARZOMEBA PISA 500MG/500MG (IMIPENEM+CILASTATINA) POLVO PARA RECONSTITUIR A SOLUCIÓN INYECTABLESynonyms: (Z)-(S)-6-carboxy-6-[(S)-2,2-dimethylcyclopropanecarboxamido]hex-5-enyl-L-cysteine, (L)-7-(2-Amino-2-carboxy-ethylsulfanyl)-2-[(2,2-dimethyl-cyclopropanecarbonyl)-amino]-hept-2-enoic acidBleomycin
go.drugbank.com/drugs/DB00290ApprovedInvestigationalIt inhibits DNA metabolism and is used as an antineoplastic, especially for solid tumors. Bleomycin A2 is used as the representative structure for Bleomycin. … A complex of related glycopeptide antibiotics from <i>Streptomyces verticillus</i> consisting of bleomycin A2 and B2 (B2 CAS # 9060-10-0).
Products: BLEOMICINA POLVO LIOFILIZADO PARA INYECCION VIAL POR 15 UI., Bleomycin for InjectionBetaine
go.drugbank.com/drugs/DB06756ApprovedInvestigationalNutraceuticalIt is a naturally occurring choline derivative commonly ingested through diet, with a role in regulating cellular hydration and maintaining cell function. … Betaine is a methyl group donor that functions in the normal metabolic cycle of methionine.
Mixtures: Pro Gest Tab, Face It Hd Perfect Bb Spf30 Pa 02Products: Dr.g Pore Purifing Toner, Betaine Anhydrous For Oral SolutionQuinine
go.drugbank.com/drugs/DB00468ApprovedInvestigationalIt was used commonly and as a bitter and flavoring agent, and is still useful for the treatment of babesiosis. … Quinine is also a mild antipyretic and analgesic and has been used in common cold preparations for that purpose.
Products: Pro-quinine - 200, Pro-quinine - 300