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Displaying results 1101 - 1110 of 2674 in total
  1. Target

    C-X-C chemokine receptor type 2

    go.drugbank.com/bio_entities/BE0010516
    TargetHumans

    Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor (PubMed:1891716). Binding of IL-8 to the receptor causes activation of neutrophils.

    Polypeptides: C-X-C chemokine receptor type 2Synonyms: GRO/MGSA receptor, IL-8 receptor type 2
  2. Target

    Tumor necrosis factor receptor superfamily member 16

    go.drugbank.com/bio_entities/BE0010540
    TargetHumans

    Low affinity receptor which can bind to NGF, BDNF, NTF3, and NTF4. … Forms a heterodimeric receptor with SORCS2 that binds the precursor forms of NGF, BDNF and NTF3 with high affinity, and has much lower affinity for mature NGF and BDNF (PubMed:24908487).

    Polypeptides: Tumor necrosis factor receptor superfamily member 16Synonyms: NGF receptor, Low affinity neurotrophin receptor p75NTR
  3. Target

    Antiviral innate immune response receptor RIG-I

    go.drugbank.com/bio_entities/BE0012418
    TargetHumans

    Innate immune receptor that senses cytoplasmic viral nucleic acids and activates a downstream signaling cascade leading to the production of type I interferons and pro-inflammatory cytokines (PubMed:15208624

    Polypeptides: Antiviral innate immune response receptor RIG-ISynonyms: RIG-I-like receptor 1
  4. Target

    Tumor necrosis factor receptor superfamily member 13C

    go.drugbank.com/bio_entities/BE0018598
    TargetHumans

    B-cell receptor specific for TNFSF13B/TALL1/BAFF/BLyS. Promotes the survival of mature B-cells and the B-cell response

    Polypeptides: Tumor necrosis factor receptor superfamily member 13CSynonyms: BAFF receptor, BLyS receptor 3
  5. Target

    Tumor necrosis factor receptor superfamily member 12A

    go.drugbank.com/bio_entities/BE0020009
    TargetHumans

    Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins

    Polypeptides: Tumor necrosis factor receptor superfamily member 12ASynonyms: Tweak-receptor
  6. Target

    Acetylcholine receptor subunit alpha-type acr-16

    go.drugbank.com/bio_entities/BE0027703
    TargetCaenorhabditis elegans

    A subunit of the levamisole-insensitive nicotinic receptor.

    Polypeptides: Acetylcholine receptor subunit alpha-type acr-16
  7. Drug

    Stearic acid

    go.drugbank.com/drugs/DB03193
    Approved

    Stearic acid (IUPAC systematic name: octadecanoic acid) is one of the useful types of saturated fatty acids that comes from many animal and vegetable fats and oils. It is a waxy solid.

    Mixtures: Jayjun Real Water Shining Cleansing Foa M, Jayjun Real Water Shining Vita Cleansing Foa M
  8. Drug

    Lazertinib

    go.drugbank.com/drugs/DB16216
    ApprovedInvestigational

    [A264289] It was approved by the FDA on August 19, 2024.[L51189] Lazertinib is used alone or in combination with other chemotherapeutic agents.[L51184] … Lazertinib is an oral, third-generation, epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI).

    Categories: Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors
  9. Drug

    Petrolatum

    go.drugbank.com/drugs/DB11058
    ApprovedInvestigational

    A colloidal system of semisolid hydrocarbons obtained from petroleum. It is used as an ointment base, topical protectant, and lubricant.

  10. Drug

    Mitomycin

    go.drugbank.com/drugs/DB00305
    ApprovedInvestigational

    [A193419] Mitomycin's cross-linking activity has resulted in its approval for the treatment of a variety of cancers - the most recent of which is an April 2020 approval for its use in low-grade Upper