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Baricitinib
go.drugbank.com/drugs/DB11817ApprovedInvestigationalthe use of baricitinib for the treatment of COVID-19 in May 2022. … [A248405] While baricitinib was granted emergency use as a treatment for COVID-19 in combination with [remdesivir] under the Emergency Use Authorization (EUA) in November 2020,[L22619] the FDA fully approved
Categories: Heterocyclic Compounds, 1-Ring, Experimental Unapproved Treatments for COVID-19Products: UNAMİTY 2 MG FİLM KAPLI TABLET, 14 ADET, UNAMİTY 4 MG FİLM KAPLI TABLET, 14 ADETSodium zirconium cyclosilicate
go.drugbank.com/drugs/DB14048ApprovedInvestigational[L2933] The treatment effect was maintained for up to 12 months.[L2933] … [L2933] Approval of the medication is supported by data from three double-blind, placebo-controlled trials and two open-label trials which showed that the onset of action was approximately 1.0 hour and
Categories: Compounds used in a research, industrial, or household settingProducts: SIMKELMA 10 G ORAL SÜSPANSİYON HAZIRLAMAK İÇİN TOZ, 28 ADET, SIMKELMA 10 G ORAL SÜSPANSİYON HAZIRLAMAK İÇİN TOZ, 11 ADETFesoterodine
go.drugbank.com/drugs/DB06702ApprovedFesoterodine is an antimuscarinic prodrug for the treatment of overactive bladder syndrome.
Products: FOSETAZ 4 MG UZATILMIŞ SALIMLI FİLM KAPLI TABLET, 28 ADET, FOSETAZ 8 MG UZATILMIŞ SALIMLI FİLM KAPLI TABLET, 28 ADETDequalinium
go.drugbank.com/drugs/DB04209Approved[A249255] First used as an antiseptic and disinfectant in the 1950s, dequalinium is still found in various OTC products to treat conditions of oral infections and inflammation. … [A249255] It is also used in vaginal tablets to treat bacterial vaginosis.[L42190]
Categories: Heterocyclic Compounds, 2-RingSynonyms: 1,1'-(1,10-Decanediyl)bis(4-amino-2-methylquinolinium) dichlorideAbatacept
go.drugbank.com/drugs/DB01281ApprovedInvestigational[L20504,L42715] Structurally, abatacept is a glycosylated fusion protein with a MALDI-MS molecular weight of 92,300 Da and it is a homodimer of two homologous polypeptide chains of 357 amino acids each … Although approved for the treatment of rheumatoid arthritis, Repligen has entered a slightly different formulation of CTLA4-Ig into clinical trials (RG2077).
Products: ORENCIA 250 MG KON.PERFUZYONLUK COZ.ICIN TOZ ICEREN FLAKON, ORENCIA® 250 MG - POLVO LIOFILIZADO PARA SOLUCIÓN INYECTABLE INTRAVENOSACobimetinib
go.drugbank.com/drugs/DB05239ApprovedInvestigationalCobimetinib is an orally active, potent and highly selective small molecule inhibiting mitogen-activated protein kinase kinase 1 (MAP2K1 or MEK1), and central components of the RAS/RAF/MEK/ERK signal transduction … It has been approved in Switzerland and the US, in combination with vemurafenib for the treatment of patients with unresectable or metastatic BRAF V600 mutation-positive melanoma.
Categories: Heterocyclic Compounds, 1-Ring, MAP Kinase Kinase 1, antagonists & inhibitorsProducts: COTELLIC FILM-COATED TABLET 20 MG, COTELLIC® (COBIMETINIB) 20 MG TABLETAS RECUBIERTASUrea C-13
go.drugbank.com/drugs/DB09510ApprovedInvestigationalUrea 13C is a urea molecule radiolabelled with the non-radioactive element carbon-13. … Radiolabelled urea is available in two forms as 13C and 14C.
Synonyms: Urea 13 C, Urea C 13Products: Diabact UBT 50 mg Tabletten, Tablet 100 mgMagnesium hydroxide
go.drugbank.com/drugs/DB09104ApprovedInvestigationalMagnesium hydroxide can be used as an antacid or a laxative in either an oral liquid suspension or chewable tablet form. … Magnesium hydroxide is an inorganic compound. It is naturally found as the mineral brucite.
Mixtures: ACİDPASS 10 MG/800 MG/165 MG ÇİĞNEME TABLETİ, 2 ADET, TRIGAST 10 MG/800 MG/165 MG ÇİĞNEME TABLETİ, 12 ADETProducts: MAGCINE 5 GR 20 POSET, MAGCINE 5 GR 10 POSETMeropenem
go.drugbank.com/drugs/DB00760ApprovedInvestigationalIn August 2017, a combination antibacterial therapy under the market name vabomere was approved for treatment of adult patients with complicated urinary tract infections (cUTI).
Categories: Heterocyclic Compounds, 2-RingSynonyms: (4R,5S,6S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]thio}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acidAgomelatine
go.drugbank.com/drugs/DB06594ApprovedInvestigationalAgomelatine is a potent agonist at melatonin receptors and an antagonist at serotonin-2C (5-HT2C) receptors, tested in an animal model of depression. … The Committee for Medical Products for Human Use (CHMP) recommended refusal of marketing authorization on 27 July 2006. The major concern was that efficacy had not been sufficiently shown.
Products: VALDOXAN 25 MG, VALDOXAN® 25 MG