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Ciclopirox
go.drugbank.com/drugs/DB01188ApprovedInvestigationalIn particular, the agent is especially effective in treating Tinea versicolor. … Ciclopirox olamine (used in preparations called Batrafen, Loprox, Mycoster, Penlac and Stieprox) is a synthetic antifungal agent for topical dermatologic treatment of superficial mycoses.
Cilastatin
go.drugbank.com/drugs/DB01597ApprovedInvestigationalSince the antibiotic, [imipenem], is one such antibiotic that is hydrolyzed by dehydropeptidase, cilastatin is used in combination with imipenem to prevent its metabolism. … [L7628] A newer triple-drug product was approved in July 2019 under the trade name Recarbrio which also contains [relebactam].[L4894]
Mixtures: Primaxin Im, Primaxin IVMidostaurin
go.drugbank.com/drugs/DB06595ApprovedInvestigationalIt was approved on April 28, 2017 and has shown to increase the overall survival rate in patients with AML as an adjunct therapy along with chemotherapeutic agents. … It was initially characterized as a potential broad-spectrum antineoplastic agent, with activity toward diverse solid and hematopoietic tumors [A19108].
Synonyms: 4'-N-benzoylstaurosporineOctocrylene
go.drugbank.com/drugs/DB09535ApprovedOctocrylene is a compound often used as an additive in sun screen, and is thought to have skin moisturizing effects because of its emollient properties. … Because of its effectiveness, the chemical has been approved across the globe for use in cosmetics and skin care products, but the concentrations of this ingredient are usually limited to no more than
Mixtures: Bullet Line, Bullet LineSerplulimab
go.drugbank.com/drugs/DB17451ApprovedInvestigationalIt was first approved in China - where it is indicated for a number of different cancers[L52963] - and has since been approved in several southeast Asian countries. … Most recently, it was approved in the EU in February 2025 for the treatment of extensive-stage small cell lung cancer.[L52968,L52953]
Ulceration of the mouth
go.drugbank.com/conditions/DBCOND0100372Drugs: Apremilast · Benzethonium · Benzocaine · Choline salicylate · Dequalinium · Lidocaine +7 moreSynonyms: Pain in oral cavityFacial Skin Wrinkles
go.drugbank.com/conditions/DBCOND0057699Drugs: Botulinum toxin type ASynonyms: Lined faceOdronextamab
go.drugbank.com/drugs/DB16684ApprovedInvestigationalThe partial clinical hold was later lifted in May 2021. … [A254187,A254197] Preliminary studies have shown that in patients with R/R NHL, the use of odronextamab does not lead to the development of neurologic toxicity; however, it can lead to the development
Elacestrant
go.drugbank.com/drugs/DB06374ApprovedInvestigational[L44918,L44948] It received a similar approval in the EU in September 2023. … [A256838,L44918] In January 2023, it was approved by the FDA for the treatment of ER-positive, HER2-negative, ESR1-mutated advanced or metastatic breast cancer.
Citric acid
go.drugbank.com/drugs/DB04272ApprovedInvestigationalNutraceuticalVet approvedA key intermediate in metabolism. It is an acid compound found in citrus fruits. The salts of citric acid (citrates) can be used as anticoagulants due to their calcium-chelating ability. … [L14120] It is also used in combination with magnesium oxide to form magnesium citrate, an osmotic laxative.[L43832]
Mixtures: Heparin Sodium In 0.9% Sodium Chloride Injection, Heparin Sodium In 5% Dextrose Injection, 25000unit/500mlCategories: Compounds used in a research, industrial, or household setting, Disinfectants (For Agents Used on Object)