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Segesterone acetate
go.drugbank.com/drugs/DB14583ApprovedSegesterone acetate is a steroidal progestin or synthetic progesterone and a 19-norprogesterone derivative with no CH3 group radical in position 6 . In animal studies, segesterone acetate was shown to be one of the most potent progestins...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesInfigratinib
go.drugbank.com/drugs/DB11886ApprovedInvestigationalWithdrawnInfigratinib is a pan-fibroblast growth factor receptor (FGFR) kinase inhibitor. … [A198963] Infitratinib is a pan-FGFR inhibitor, as it is an ATP-competitive inhibitor of all four FGFR receptor subtypes.
Categories: Cytochrome P-450 Substrates, P-glycoprotein inhibitorsTauroursodeoxycholic acid
go.drugbank.com/drugs/DB08834ApprovedInvestigationalWithdrawnTauroursodeoxycholic acid, also known as ursodoxicoltaurine, is a highly hydrophilic tertiary bile acid that is produced in humans at a low concentration. It is a taurine conjugate of ursodeoxycholic acid with comparable therapeutic effi...
Fluciclovine (18F)
go.drugbank.com/drugs/DB13146ApprovedInvestigationalFluciclovine is a [18F]-tagged synthetic analog of the amino acid L-leucine. It presents excellent diagnostic properties to be used in positron emission tomography (PET) imaging. The structure of fluciclovine allows it to be uptaken by t...
Celivarone
go.drugbank.com/drugs/DB16012InvestigationalPlacebo Controlled Double-blind Dose Ranging Study of the Efficacy and Safety of SSR149744C 50, 100, 200 or 300 Mg OD With Amiodarone as Calibrator for the Maintenance of Sinus Rhythm in Patients With Recent
Low affinity immunoglobulin gamma Fc region receptor III-B
go.drugbank.com/bio_entities/BE0000901TargetHumansReceptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG.
Polypeptides: Low affinity immunoglobulin gamma Fc region receptor III-BSynonyms: IgG Fc receptor III-1Low affinity immunoglobulin gamma Fc region receptor II-b
go.drugbank.com/bio_entities/BE0002099TargetHumansReceptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. … Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor.
Polypeptides: Low affinity immunoglobulin gamma Fc region receptor II-bSynonyms: IgG Fc receptor II-bTransient receptor potential cation channel subfamily V member 6
go.drugbank.com/bio_entities/BE0005102TransporterTargetHumansCalcium selective cation channel that mediates Ca(2+) uptake in various tissues, including the intestine (PubMed:11097838, PubMed:11248124, PubMed:11278579, PubMed:15184369, PubMed:23612980, PubMed:29258289). Important for normal Ca(2+) ...
Polypeptides: Transient receptor potential cation channel subfamily V member 6Transient receptor potential cation channel subfamily M member 5
go.drugbank.com/bio_entities/BE0020643TargetHumansMonovalent cation-selective ion channel activated by intracellular Ca(2+) in a voltage- and temperature-dependent manner (PubMed:14634208). Mediates the transport of Na(+), K(+) and Cs(+) ions equally well (PubMed:14634208). Activated di...
Polypeptides: Transient receptor potential cation channel subfamily M member 5Synonyms: Long transient receptor potential channel 5Beta carotene
go.drugbank.com/drugs/DB06755ApprovedNutraceuticalBeta-carotene, with the molecular formula C40H56, belongs to the group of carotenoids consisting of isoprene units. The presence of long chains of conjugated double bonds donates beta-carotene with specific colors. It is the most abundan...
Mixtures: Virt-Pn, PR Natal 430