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Displaying results 1111 - 1120 of 10000 in total
  1. Drug

    Parathyroid hormone

    go.drugbank.com/drugs/DB05829
    ApprovedInvestigational

    Preos is a registered trade mark owned by NPS Pharmaceuticals, Inc. The name Preos and the New Drug Application is pending approval by the U.S. Food and Drug Administration (FDA). … Parathyroid hormone (PTH) is a single-chain polypeptide composed of 84 amino acids.

    Synonyms: PTH(1-84), rPTH(1-84)
  2. Drug

    Simenepag isopropyl

    go.drugbank.com/drugs/DB12977
    Investigational

    Simenepag isopropyl has been used in trials studying the treatment of Ocular Hypertension and Glaucoma, Open-Angle.

  3. Drug

    Evodenoson

    go.drugbank.com/drugs/DB12295
    Investigational

    Evodenoson has been used in trials studying the treatment of Open-angle Glaucoma and Ocular Hypertension.

    Categories: Heterocyclic Compounds, 1-Ring
  4. Drug

    Taprenepag

    go.drugbank.com/drugs/DB12623
    Investigational

    Taprenepag has been used in trials studying the treatment of Ocular Hypertension and Glaucoma, Open-Angle.

    Categories: Receptors, Prostaglandin E, EP2 Subtype, agonists
  5. Drug

    Bamosiran

    go.drugbank.com/drugs/DB12256
    Investigational

    Bamosiran has been used in trials studying the treatment of Glaucoma, Ocular Hypertension, and Open Angle Glaucoma.

  6. Drug

    Carbazochrome

    go.drugbank.com/drugs/DB09012
    ApprovedWithdrawn

    Carbazochrome is a hemostatic agent that promotes clotting, preventing blood loss from open wounds. It is an oxidation product of adrenaline which enhances the microcirculatory tone [A19747]. … It is not FDA-approved but is available as tablets or IM/SC injections in the treatment of hemorrhages in a number of countries.

    Mixtures: Igatan FCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inhibitors
  7. Drug

    N4-Hydroxycytidine

    go.drugbank.com/drugs/DB15660
    Experimental

    N4-Hydroxyctidine, or EIDD-1931, is a ribonucleoside analog which induces mutations in RNA virions. … [A193017] N4-hydroxycytodine has been shown to inhibit SARS-CoV-2 as well as other human and bat coronaviruses in mice and human airway epithelial cells.

    Synonyms: beta-D-N-4-Hydroxycytidine, 4-N-HydroxycytidineCategories: Heterocyclic Compounds, 1-Ring
  8. Drug

    MRK-409

    go.drugbank.com/drugs/DB13993
    Experimental

    MRK-409 is a GABA-A receptor agonist [A31972].

  9. Pathway

    Non-Ketotic Hyperglycinemia

    smpdb.ca/view/SMP0000223
    Disease

    Non Ketotic Hyperglycinemeia (Glycine encephalopathy; Glycine cleavage system deficiency; NKH) is caused by mutations in several genes in the mitochondrial glycine cleavage system. These include the genes encoding P protein (GLDC), T pro...

    Drugs: Pyridoxal phosphate · Tetrahydrofolic acid · Ademetionine · Pyruvic acid · Arginine · Adenosine phosphate +26 more
    Enzymes: Betaine--homocysteine S-methyltransferase 1
  10. Pathway

    3-Phosphoglycerate Dehydrogenase Deficiency

    smpdb.ca/view/SMP0000721
    Disease

    3-Phosphoglycerate dehydrogenase deficiency is a disorder of L-serine biosynthesis that is characterized by congenital microcephaly, psychomotor retardation, and seizures.The disorder is caused by homozygous or compound heterozygous or h...

    Drugs: Pyridoxal phosphate · Tetrahydrofolic acid · Ademetionine · Pyruvic acid · Arginine · Adenosine phosphate +26 more
    Enzymes: Betaine--homocysteine S-methyltransferase 1