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Displaying results 1131 - 1140 of 10000 in total
  1. Drug

    Dorzolamide

    go.drugbank.com/drugs/DB00869
    ApprovedInvestigational

    [L11377] It works by blocking an enzyme in the ciliary process that regulates ion balance and fluid pressure in the eyes. … [A1304] First marketed in 1995,[A190624] dorzolamide is available in ophthalmic solutions as monotherapy marketed as Trusopt [L11377] or in combination with [timolol] as Cosopt PF.[L11380]

    Mixtures: DORZOLAMIDE E TIMOLOLO EG, DORZOLAMIDE E TIMOLOLO EG
  2. Drug

    Calaspargase pegol

    go.drugbank.com/drugs/DB14730
    ApprovedInvestigational

    Asparagine is incorporated into most proteins, and the synthesis of proteins is stopped when asparagine is absent, which inhibits RNA and DNA synthesis, resulting in a halt in cellular proliferation. … Asparaginase is an important agent used to treat acute lymphoblastic leukemia (ALL) [A40270].

    Categories: Compounds used in a research, industrial, or household setting
  3. Drug

    Spirapril

    go.drugbank.com/drugs/DB01348
    ApprovedInvestigational

    ACE inhibitors are used primarily in treatment of hypertension and congestive heart failure. … Spirapril is an ACE inhibitor antihypertensive drug used to treat hypertension. Spirapril is converted to the active spiraprilat after administration.

    Categories: Agents Acting on the Renin-Angiotensin System
  4. Drug

    Talniflumate

    go.drugbank.com/drugs/DB09295
    Investigational

    Talniflumate has been approved for approximately 20 years in Argentina other countries (excluding the United States, Europe, and Japan) [L1405]. … In addition, it is used in inflammatory conditions such as rheumatoid arthritis.

  5. Drug

    Briakinumab

    go.drugbank.com/drugs/DB05459
    Investigational

    As of 2011 drug development for psoriasis has been discontinued in the U.S. and Europe.

  6. Drug

    Bupivacaine

    go.drugbank.com/drugs/DB00297
    ApprovedInvestigational

    Bupivacaine is a widely used local anesthetic agent.

    Mixtures: Marcaine E, Marcaine ESynonyms: 1-Butyl-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide
  7. Drug

    Doconexent

    go.drugbank.com/drugs/DB03756
    ApprovedInvestigational

    It is an omega-3 fatty acid and primary structural component of the human brain, cerebral cortex, skin, and retina thus plays an important role in their development and function.

    Mixtures: Live-well™ Toco-E Capsule, Virt-Pn DHASynonyms: 22:6(n-3)
  8. Drug

    Acarbose

    go.drugbank.com/drugs/DB00284
    ApprovedInvestigational

    Acarbose is a complex oligosaccharide that acts as an inhibitor of several enzymes responsible for the breakdown of complex carbohydrates in the intestines. … Acarbose is therefore used in conjunction with diet, exercise, and other pharmacotherapies for the management of blood sugar levels in patients with type 2 diabetes.

    Categories: Drugs Used in Diabetes
  9. Drug

    Lactic acid

    go.drugbank.com/drugs/DB04398
    ApprovedInvestigationalVet approved

    (From Stedman, 26th ed) Sodium lactate is the sodium salt of lactic acid, and has a mild saline taste. … Lactic acid was one of active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved by the FDA on May 2020.[L14120]

    Mixtures: SOLUCION DP PISA 2.5%(MODIFICADA EN MAGNESIO Y LACTATO), Dextrose in Lactated RingersProducts: Lactinol-E
  10. Drug

    Bronopol

    go.drugbank.com/drugs/DB13960
    Approved

    Compared to other aliphatic halogen-nitro compounds, bronopol is more stable to hydrolysis in aqueous media under normal conditions [A32792]. … First synthesized in 1897, bronopol was primarily used as a preservative for pharmaceuticals and was registered in the United States in 1984 for use in industrial bactericides, slimicides and preservatives

    Categories: Compounds used in a research, industrial, or household setting