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Metoprolol
go.drugbank.com/drugs/DB00264ApprovedInvestigational[A175162] Metoprolol was developed since 1969 by US Pharmaceutical Holdings I and FDA approved in 1978.[L5527] … [A175159, L5530] The possibility of the generation of these formulations comes from the lower systemic bioavailability of the succinate derivative.
Categories: Antihypertensive Agents Indicated for HypertensionProducts: METOPROLOL ABZ 0.K. 50MG, METOPROLOL ABZ 0.K. 100MGAmorolfine
go.drugbank.com/drugs/DB09056ApprovedWithdrawnIt is approved for sale over the counter in Australia and the UK (recently re-classified to over the counter status), and is approved for the treatment of toenail fungus by prescription in other countries … It is available in the form of a 5% amorolfine nail lacquer used to treat onychomycosis (fungal infection of the toe- and fingernails).
Categories: Antifungals for Topical Use, Antifungals for Dermatological UseGelatin
go.drugbank.com/drugs/DB11242ApprovedInvestigationalVet approvedWithdrawnAn increasing number of novel applications have been found for collagen and gelatin.[A32426] Gelatin is generally recognized as safe (GRAS) by the FDA to be a non-hazardous food or food ingredient. … [A32432] Some alternative raw substances have recently garnered attention from both researchers and the industry not only because they overcome religious concerns shared by both Jews and Muslims but
Mixtures: Gelaspan Solution for infusionRevefenacin
go.drugbank.com/drugs/DB11855ApprovedInvestigational[A40025] From the LAMA group, revefenacin is the first once-daily nebulized LAMA treatment.[A40026] It was developed by Theravance Biopharma and FDA approved on November 9, 2018.[L4818] … The LAMA group falls into a parent category known as long-acting inhaled bronchodilators and this type of agents are recommended as a maintenance therapy for chronic obstructive pulmonary disease (COPD
Categories: Drugs for Obstructive Airway DiseasesIobenguane
go.drugbank.com/drugs/DB06704ApprovedInvestigationalThe radioisotope used can either be iodine-123 for imaging or iodine-131 for destruction of tissues that metabolize noradrenaline. … Iodine 123 is a cyclotron-produced radionuclide that decays to Te 123 by electron capture. Images are produced by a I123 MIBG scintigraphy. FDA approved on September 19, 2008.
Categories: Compounds used in a research, industrial, or household settingElbasvir
go.drugbank.com/drugs/DB11574ApprovedApproved in January 2016 by the FDA, Zepatier is indicated for the treatment of HCV genotypes 1 and 4 with or without [ribavirin] depending on the presence of resistance-associated amino acid substitutions … [A193257] While these results are suggestive of antiviral efficacy, follow-up clinical trials are required to validate elbasvir as a potential therapy against SARS-CoV-2.
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseTestosterone cypionate
go.drugbank.com/drugs/DB13943ApprovedInvestigationalTestosterone cypionate is a synthetic derivative of testosterone in the form of an oil-soluble 17 (beta)-cyclopentylpropionate ester. … It was developed by the company Pharmacia and Upjohn and FDA approved on July 25, 1979.
Protein c-Fos
go.drugbank.com/bio_entities/BE0001126TargetHumansNuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. … In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites.
Polypeptides: Protein c-FosSynonyms: Cellular oncogene fos, Proto-oncogene c-FosNonoxynol-9
go.drugbank.com/drugs/DB06804ApprovedWithdrawnIt is the most commonly used spermicidal contraceptive in the UK and the USA. In several European countries, spermicides are no longer on the market. … N-9 has been in use for more than 30 years as an over-the-counter (OTC) drug in creams, gels, foams and condom lubricants.
Categories: Hormonal Contraceptives for Systemic Use, Contraceptive Agents, MaleZotepine
go.drugbank.com/drugs/DB09225ApprovedWithdrawnIt was designed and synthesized by Fujisawa Pharmaceutical Co Ltd.[A31855] It has been used as an antipsychotic in Japan, India and some places in Europe like UK and Germany since 1980's. … In the EMA, by 2015 it was under pharmacovigilance studies for the potential treatment of acute renal failure.[L1314]