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Displaying results 1151 - 1160 of 10000 in total
  1. Drug

    Methylnaltrexone

    go.drugbank.com/drugs/DB06800
    ApprovedInvestigational

    Methylnaltrexone is a pheriphally-acting μ-opioid antagonist that acts on the gastrointestinal tract to decrease opioid-induced constipation without producing analgesic effects or withdrawal symptoms.

    Categories: Alimentary Tract and MetabolismProducts: Relistor Solution For Injection 12mg/0.6mL, RELISTOR (TM) (SUBCUTANEOUS INJECTION,12MG/0.6ML PER VIAL)
  2. Drug

    Avelumab

    go.drugbank.com/drugs/DB11945
    ApprovedInvestigational

    [A261496] On September 18 and December 18 of the same year, it was also granted approval by EMA [L48126] and Health Canada,[L48171] respectively. … [A261496] Avelumab was first approved by the FDA on March 23, 2017.

    Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsProducts: BAVENCIO CONCENTRATE FOR SOLUTION FOR INFUSION 200MG/10ML, BAVENCIO 200 mg/10mL concentrate for solution for infusion
  3. Drug

    Tafamidis

    go.drugbank.com/drugs/DB11644
    ApprovedInvestigational

    Tafamidis and tafamidis meglumine (FX-1006A) are benzoxazole derivatives[A27206] developed by FoldRX.[A189717] Tafamidis is structurally similar to diflusinal. … [A189717] Tafamidis was granted an EMA market authorisation on 16 November 2011[L6247] and FDA approval on 3 May 2019.[L11280]

    Categories: Hormones, Hormone Substitutes, and Hormone AntagonistsProducts: VYNDAQEL SOFT GELATIN CAPSULE 20MG
  4. Drug

    Urofollitropin

    go.drugbank.com/drugs/DB00094
    ApprovedVet approvedWithdrawn

    It consists of two non-covalently linked, non-identical glycoproteins designated as the alpha- and beta- subunits. The alpha- and beta- subunits have 92 and 111 amino acids. … The alpha subunit is glycosylated at Asn 51 and Asn 78 while the beta subunit is glycosylated at Asn 7 and Asn 24.

    Categories: Amino Acids, Peptides, and Proteins, Gonadotropins and AntigonadotropinsProducts: BRAVELLE POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 75 IU, Fostimon 75 IU powder and solvent for solution for injection
  5. Target

    Splicing factor, proline- and glutamine-rich

    go.drugbank.com/bio_entities/BE0008965
    TargetHumans

    The SFPQ-NONO-NR5A1 complex binds to the CYP17 promoter and regulates basal and cAMP-dependent transcriptional activity. … DNA- and RNA binding protein, involved in several nuclear processes.

    Polypeptides: Splicing factor, proline- and glutamine-rich
  6. Drug

    Podophyllin

    go.drugbank.com/drugs/DB09094
    Approved

    Podophyllin is a resin extracted from the roots of _Podophyllum peltatum_ (American mandrake) and _Podophyllum emodi_, which contains numerous compounds, amongst which is podophyllin (as well as the drug

    Mixtures: PODOPHYLLIN PAINT, CO.Categories: Skin and Mucous Membrane Agents
  7. Drug

    Pentoxyverine

    go.drugbank.com/drugs/DB11186
    ApprovedWithdrawn

    Pentoxyverine, also referred to as carbetapentane, is a non-opioid central acting antitussive with antimuscarinic, anticonvulsant [A32717], and local anesthetic properties. … It is an active ingredient in over-the-counter cough suppressants in combination with guaifenesin and H1-receptor antagonists [A32160].

    Categories: Cough and Cold PreparationsProducts: PENTOXYVERIN AL 19MG/ML
  8. Drug

    Cod liver oil

    go.drugbank.com/drugs/DB11321
    ApprovedNutraceuticalVet approved

    It is used as an adjunct treatment and preventative therapy of rickets, osteomalacia and osteoporosis while meeting the consumption criteria. … Cod liver oil is extracted from the liver of cod fish and mainly consists of omega-3 fatty acids, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA).

    Mixtures: CURACID Dermal for cuts and burnsCategories: Diet, Food, and Nutrition
  9. Drug

    Orlistat

    go.drugbank.com/drugs/DB01083
    ApprovedInvestigational

    Obesity-related complications lead to significant personal and economic burden by reducing quality of life and increasing the cost of healthcare. … [L11130] This drug is a generally well-tolerated and effective weight-loss aid and is now available in both over-the-counter[L31963] and prescription preparations, depending on the dosage quantity.

    Categories: Alimentary Tract and MetabolismProducts: ORLISTAT 120MG, XENICAL CAPSULE 120MG
  10. Target

    Cocaine- and amphetamine-regulated transcript protein

    go.drugbank.com/bio_entities/BE0000867
    TargetHumans

    Satiety factor closely associated with the actions of leptin and neuropeptide Y; this anorectic peptide inhibits both normal and starvation-induced feeding and completely blocks the feeding response induced … It promotes neuronal development and survival in vitro

    Polypeptides: Cocaine- and amphetamine-regulated transcript protein