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Displaying results 1161 - 1170 of 10000 in total
  1. Drug

    Pixantrone

    go.drugbank.com/drugs/DB06193
    ApprovedWithdrawn

    Pixantrone was designed to treat relapsed or refractory aggressive non-Hodgkin's lymphoma(NHL) in patients who have failed two prior lines of therapy. [2] For patients suffering from NHL, first line therapies … Pixantrone dimaleate, administered intravenously, was designed by Cell Therapeutics Incorporated as an alternative second line therapy in refractory or relapsed NHL.

    Categories: Topoisomerase II Inhibitors, Heterocyclic Compounds, 2-RingSynonyms: 6,9-bis((2-aminoethyl)amino)benzo(g)isoquinoline-5,10-dione
  2. Drug

    Valine

    go.drugbank.com/drugs/DB00161
    ApprovedInvestigationalNutraceutical

    Valine is a branched-chain essential amino acid that has stimulant activity. It promotes muscle growth and tissue repair. It is a precursor in the penicillin biosynthetic pathway.

    Mixtures: Aminosyn II 7% M In 10% Dextrose(dual Chamber), Aminosyn II in DextroseSynonyms: 2-Amino-3-methylbutyric acid, (2S)-2-Amino-3-methylbutanoic acid
  3. Drug

    Alanine

    go.drugbank.com/drugs/DB00160
    ApprovedInvestigationalNutraceutical

    Alanine is a non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. … It is involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and the central nervous system.

    Mixtures: Aminosyn II 7% M In 10% Dextrose(dual Chamber), Aminosyn II in DextroseSynonyms: L-α-alanine, (S)-2-aminopropanoic acid
  4. Indication

    Moderate to Severe Glabellar Frown Lines

    go.drugbank.com/conditions/DBCOND0042188
    Drugs: LetibotulinumtoxinA · TrenibotulinumtoxinE
    Synonyms: Moderate to Severe Glabellar Line, Moderate-severe Glabellar Lines
  5. Target

    4-hydroxy-3-methylbut-2-enyl diphosphate reductase

    go.drugbank.com/bio_entities/BE0004045
    TargetEscherichia coli (strain K12)

    Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). … In vitro, can also hydrate acetylenes to aldehydes and ketones via anti-Markovnikov/Markovnikov addition (PubMed:22948824).

    Synonyms: 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate reductase
  6. Target

    Integrin alpha-5

    go.drugbank.com/bio_entities/BE0008988
    TargetHumans

    It recognizes the sequence R-G-D in its ligands.

    Synonyms: CD49 antigen-like family member E
  7. Drug

    Leucine

    go.drugbank.com/drugs/DB00149
    ApprovedInvestigationalNutraceutical

    An essential branched-chain amino acid important for hemoglobin formation.

    Salts: L-Leucine hydrochlorideMixtures: Aminosyn II 7% M In 10% Dextrose(dual Chamber), Aminosyn II in Dextrose
  8. Indication

    Diabetic Ketoacidosis

    go.drugbank.com/conditions/DBCOND0000979
    Drugs: Insulin aspart · Insulin lispro · Somatostatin
    Synonyms: Ketoacidosis in diabetes mellitus
  9. Drug

    Calcium hypochlorite

    go.drugbank.com/drugs/DB15912
    Investigational

    Mixtures: POLYLAB T-EUSOL (SOLUTION A & B), POLYLAB T-EUSOL( SOLUTION A & B)Synonyms: Hypochlorite de calcium
  10. Drug

    Silver oxide

    go.drugbank.com/drugs/DB15668
    Investigational

    Synonyms: Silver(I) oxideProducts: Fullerene Silver Ion Bacteriostatic Solution