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Displaying results 1161 - 1170 of 10000 in total
  1. Drug

    Blinatumomab

    go.drugbank.com/drugs/DB09052
    ApprovedInvestigational

    In March 2018, it was approved under the FDA’s accelerated approval program for the treatment of CD19-positive B-cell precursor ALL in first or second complete remission with minimal residual disease ( … [A254836,L44311] CD3 is an antigen expressed on the surface of T-cells, while CD19 is mostly expressed on the surface of malignant B-cells.

  2. Drug

    Mitotane

    go.drugbank.com/drugs/DB00648
    ApprovedInvestigational

    It has been in use since 1959 for the treatment of inoperable adrenocortical carcinoma[A263010] and is used off-label for the management of Cushing's syndrome.[A263016] … Mitotane is an adrenolytic isomer of the insecticide dichlorodiphenyldichloroethane (DDD) - itself a metabolite of dichlorodiphenyltrichloroethane (DDT) - that inhibits cells of the adrenal cortex and

  3. Drug

    Naloxegol

    go.drugbank.com/drugs/DB09049
    ApprovedInvestigational

    It was approved by the FDA in September 2014 and is indicated for the treatment of opioid-induced constipation (OIC) in adult patients with chronic non‑cancer pain.

    Categories: Compounds used in a research, industrial, or household setting
  4. Indication

    Bone Giant Cell Tumor

    go.drugbank.com/conditions/DBCOND0112909
    Drugs: Denosumab
    Synonyms: Bone giant cell tumour, Giant Cell Tumors of Bone
  5. Indication

    Bone Marrow Transplant Rejection

    go.drugbank.com/conditions/DBCOND0030791
    Drugs: Cyclosporine
    Synonyms: Rejection of bone marrow graft, Bone Marrow Transplant Rejection
  6. Indication

    Bone and Joint Infections

    go.drugbank.com/conditions/DBCOND0051086
    Drugs: Amikacin · Amoxicillin · Aztreonam · Cefoperazone · Cefotetan · Cefoxitin +10 more
    Synonyms: Bone and joint infection, Bone and Joint Infections
  7. Drug

    Casirivimab

    go.drugbank.com/drugs/DB15941
    ApprovedInvestigational

    [L39130,L39135] Full safety and efficacy data are not yet available, and further evaluation of this investigational therapy will continue.[L23539,L23529,L14303] … [A221495] On November 21 2020, the FDA authorized emergency approval of REGEN-COV2 to treat mild to moderate COVID-19 in patients aged 12 years and older.

  8. Drug

    Adalimumab

    go.drugbank.com/drugs/DB00051
    ApprovedInvestigational

    This drug is available in a prefilled syringe form and convenient pen form for subcutaneous self-administered doses.[A39983] Several biosimilars to adalimumab. … A biosimilar marketed as Hyrimoz, a high-concentration formulation of adalimumab, is also available.[L45643,L45818].

    International brands: Humira PenProducts: AMGEVITA 40MG ILO I E PEN, AMGEVITA 40 MG ILO I E PEN
  9. Drug

    Atropine

    go.drugbank.com/drugs/DB00572
    ApprovedInvestigationalVet approved

    Oral atropine is only available in combination products. … [A251670,L42835] Atropine is generally available as a sulfate salt and can be administered by intravenous, subcutaneous, intramuscular, intraosseous, endotracheal and ophthalmic methods.

    Products: N/a, Atropin Accord 0,1 mg/ml Injektionslösung in einer Fertigspritze
  10. Drug

    Leniolisib

    go.drugbank.com/drugs/DB16217
    ApprovedInvestigational

    The FDA approved leniolisib on March 24, 2023, making it the first treatment for activated phosphoinositide 3-kinase delta syndrome (APDS). … [L45753] Investigations for using leniolisib in primary Sjögren’s syndrome are ongoing.[A258468]