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Glyburide
go.drugbank.com/drugs/DB01016ApprovedInvestigationalGlyburide is a second generation sulfonylurea used to treat patients with diabetes mellitus type II. … [L8117] A formulation with metformin was granted FDA approval on on 31 July 2000.[L8120]
Synonyms: 5-chloro-N-(2-(4-((((cyclohexylamino)carbonyl)amino)sulfonyl)phenyl)ethyl)-2-methoxybenzamideProducts: Nu-glyburide Tab 5mg, Nu-glyburide Tab 2.5mgOctinoxate
go.drugbank.com/drugs/DB09496ApprovedInvestigationalOctinoxate is a cinnamate ester and common ingredient in sunscreen and other skin care products to minimize DNA photodamage. … It was originally developed in 1950's as an organic UV-B filter that absorbs UV-B rays from sun.
Mixtures: Noevir N5, The Cover Classic Foundation SPF 24, No. N3Categories: Compounds used in a research, industrial, or household settingSalicylic acid
go.drugbank.com/drugs/DB00936ApprovedInvestigationalVet approvedA compound obtained from the bark of the white willow and wintergreen leaves, and also prepared synthetically. It has bacteriostatic, fungicidal, and keratolytic actions.
Mixtures: KINOR NF, KINOR NFProducts: ACIDO SALICILICO NA, JUMISO No pain No gain AC CURE spotTretinoin
go.drugbank.com/drugs/DB00755ApprovedInvestigationalNutraceutical[A257474] It is an oxidation product in the physiological pathway of vitamin A metabolism. … Tretinoin, also known as all-trans-retinoic acid (ATRA), is a naturally occurring derivative of [vitamin A] (retinol).
Synonyms: Vitamin A acid, all-trans-Vitamin A acidInternational brands: Stieva-APrednisolone acetate
go.drugbank.com/drugs/DB15566ApprovedInvestigationalVet approvedPrednisolone acetate is a [prednisolone] molecule bound to an acetate functional group by an ester bond.[L9449] Prednisolone acetate was granted FDA approval in 1955.[L9449]
Products: PRED NFPantothenic acid
go.drugbank.com/drugs/DB01783ApprovedInvestigationalNutraceuticalVet approvedPantothenic acid, also called pantothenate or vitamin B5 (a B vitamin), is a water-soluble vitamin discovered by Roger J. Williams in 1919. … Pantothenic acid is an ingredient in some hair and skin care products.
Mixtures: Folika-NC, Soluvit NProducts: Pantothenic Acid Tab 100mg Nu LifeFluorometholone
go.drugbank.com/drugs/DB00324ApprovedInvestigationalA glucocorticoid employed, usually as eye drops, in the treatment of allergic and inflammatory conditions of the eye. It has also been used topically in the treatment of various skin disorders.
Mixtures: FLUFORTE-N-LIQUIFILMProducts: FLUMETOL NF OFTENOIndapamide
go.drugbank.com/drugs/DB00808ApprovedInvestigational[A204155] Characterized by an office blood pressure of ≥140/90, hypertension is pervasive and impacts an estimated 25% of adults globally. … [A204134,A204161] Indapamide is characterized by both a methylindoline and a sulfamoyl chlorobenzamide functional group, with the former being largely responsible for the molecule’s lipid solubility
Mixtures: BIPRETERAX N 5MG/1.25MG, BIPRETERAX N 5MG/1.25MGProducts: Nu-indapamide, Nu-indapamide - Tab 2.5mgDienogest
go.drugbank.com/drugs/DB09123ApprovedInvestigationalDienogest is an orally-active semisynthetic progestogen which also possesses the properties of 17α-hydroxyprogesterone. It is a derivative of 19-nortestosterone and has antiandrogenic properties. … It is primarily used as a contraceptive in combination with ethinylestradiol, or in other combination form pills approved in United States and Europe however it is not available in the US by itself.
Products: Nra-dienogestTrabectedin
go.drugbank.com/drugs/DB05109ApprovedInvestigationalTrabectedin has a unique mechanism of action. It binds to the minor groove of DNA interfering with cell division and genetic transcription processes and DNA repair machinery. … Food and Drug Administration (FDA) have approved trabectedin as an orphan drug in soft tissue sarcomas and ovarian cancer.
Categories: Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic IndexProducts: Nat-trabectedin