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Japanese encephalitis virus strain sa 14-14-2 antigen (formaldehyde inactivated)
go.drugbank.com/drugs/DB10769ApprovedInvestigationalSynonyms: Japanese encephalitis virus strain SA 14-14-2 antigen (formaldehyde inactivated)Products: IXIARO Suspension for Injection 0.5ml in pre-filled syringeCoagulation factor XIII A chain
go.drugbank.com/bio_entities/BE0000004TargetEnzymeHumansFactor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl-epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot
Polypeptides: Coagulation factor XIII A chainSynonyms: Transglutaminase A chain, Protein-glutamine gamma-glutamyltransferase A chainL-lactate dehydrogenase A chain
go.drugbank.com/bio_entities/BE0000425TargetHumansInterconverts simultaneously and stereospecifically pyruvate and lactate with concomitant interconversion of NADH and NAD(+)
Polypeptides: L-lactate dehydrogenase A chainSynonyms: LDH-ADNA topoisomerase 4 subunit A
go.drugbank.com/bio_entities/BE0000429TargetHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)Performs the decatenation events required during the replication of a circular DNA molecule.
Polypeptides: DNA topoisomerase 4 subunit ASynonyms: Topoisomerase IV subunit ADNA topoisomerase 4 subunit A
go.drugbank.com/bio_entities/BE0000798TargetEscherichia coli (strain K12)MukB stimulates the relaxation activity of topoisomerase IV and also has a modest effect on decatenation (PubMed:20921377).
Polypeptides: DNA topoisomerase 4 subunit ASynonyms: Topoisomerase IV subunit ARibose-5-phosphate isomerase A
go.drugbank.com/bio_entities/BE0001628TargetShigella flexneriCatalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
Polypeptides: Ribose-5-phosphate isomerase ASynonyms: Phosphoriboisomerase AGlyceraldehyde-3-phosphate dehydrogenase A
go.drugbank.com/bio_entities/BE0002057TargetEscherichia coli (strain K12)The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction … The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.
Polypeptides: Glyceraldehyde-3-phosphate dehydrogenase ASynonyms: GAPDH-AEndo-1,4-beta-xylanase A
go.drugbank.com/bio_entities/BE0002766TargetStreptomyces lividansContributes to hydrolyze hemicellulose, the major component of plant cell-walls. XLNA and XLNB seem to act sequentially on the substrate to yield xylobiose and xylose as carbon sources.
Polypeptides: Endo-1,4-beta-xylanase ASynonyms: Xylanase A, 1,4-beta-D-xylan xylanohydrolase ARibose-5-phosphate isomerase A
go.drugbank.com/bio_entities/BE0003268TargetHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
Polypeptides: Ribose-5-phosphate isomerase ASynonyms: Phosphoriboisomerase AEphrin type-A receptor 7
go.drugbank.com/bio_entities/BE0004140TargetHumansHas a repellent activity on axons and is for instance involved in the guidance of corticothalamic axons and in the proper topographic mapping of retinal axons to the colliculus. … Among GPI-anchored ephrin-A ligands, EFNA5 is a cognate/functional ligand for EPHA7 and their interaction regulates brain development modulating cell-cell adhesion and repulsion.
Polypeptides: Ephrin type-A receptor 7