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Fludrocortisone
go.drugbank.com/drugs/DB00687ApprovedInvestigationalFludrocortisone is a synthetic mineralocorticoid used in conjunction with [hydrocortisone] to replace missing endogenous corticosteroids in patients with adrenal insufficiency. … [A187169,A187187] It is functionally similar to [aldosterone], the body's primary endogenous mineralocorticoid, and is structurally analogous to [cortisol], differing only by a fluorine atom at the 9-position
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: ASTONIN-H 0,1 MG TABLET, 100 ADET, FLORINEF TABLET 0.1 mgAlfentanil
go.drugbank.com/drugs/DB00802ApprovedIllicitInvestigationalIt produces an early peak analgesic effect and fast recovery of consciousness. … Alfentanil is effective as an anesthetic during surgery, for supplementation of analgesia during surgical procedures, and as an analgesic for critically ill patients.
Synonyms: N-(1-(2-(4-Ethyl-5-oxo-2-tetrazolin-1-yl)ethyl)-4-(methoxymethyl)-4-piperidyl)propionanilideCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesEdetate calcium disodium anhydrous
go.drugbank.com/drugs/DB14598ApprovedInvestigational[L12774] It is on the World Health Organization Model List of Essential Medicines.[A204173] Edetate calcium disodium was granted FDA approval on 16 July 1953.[L12774]
Categories: Compounds used in a research, industrial, or household setting, Cytochrome P-450 CYP3A InhibitorsProducts: LIBENTA AMPUL 2ML, 10 ADET, LIBENTA AMPUL 2ML, 100 ADETStrontium ranelate
go.drugbank.com/drugs/DB09267ApprovedWithdrawnAvailable for prescription use for a time in some parts of the world as Protelos (strontium ranelate) 2 g granules for oral suspension by Servier, it was ultimately discontinued in 2016-2017 owing to an … It is therefore promoted as a "dual action bone agent" (DABA) indicated for use in treatment of severe osteoporosis.
Mixtures: FULLBONE D3 2 G/800 IU EFERVESAN TABLET, 30 ADET, FULLBONE D3 2 G/800 IU EFERVESAN TABLET, 60 ADETProducts: RASBY 2 G ORAL SUSPANSIYON ICIN GRANUL ,100 PAKET, DIOSS 2 G EFERVESAN TABLET, 56 ADETPhenylephrine
go.drugbank.com/drugs/DB00388ApprovedInvestigational[A187370] The action of phenylephrine, or neo-synephrine, was first described in literature in the 1930s.[A187376] Phenylephrine was granted FDA approval in 1939.[L9413] … Phenylephrine is an alpha-1 adrenergic receptor agonist used to treat hypotension,[L9416,L9410] dilate the pupil,[L9413] and induce local vasoconstriction.
Synonyms: (−)-m-hydroxy-α-(methylaminomethyl)benzyl alcohol, l-(3-Hydroxyphenyl)-N-methylethanolamineMixtures: DAYCOLD-HOT 500/10/15/100 MG SAŞE ,20 SAŞE, DEFLU 24/0.2/0.5 mg/ml ŞURUP, 100 MLRoflumilast
go.drugbank.com/drugs/DB01656ApprovedInvestigational[A251385] PDE4 is a major cyclic-3',5′-adenosinemonophosphate (cyclic AMP, cAMP)-metabolizing enzyme [L37564] expressed on nearly all immune and pro-inflammatory cells, in addition to structural cells … Roflumilast is a highly selective phosphodiesterase-4 (PDE4) inhibitor.
Categories: Phosphodiesterase 4 Inhibitors, Cytochrome P-450 SubstratesProducts: ROFLUNG 0,5 MG SAŞE ,30 SAŞE, ROFLUNG 0,5 MG SAŞE ,90 SAŞEIsoprenaline
go.drugbank.com/drugs/DB01064ApprovedInvestigational[L33204] Isoprenaline was granted FDA approval on 19 February 1948.[L33155] … Isoprenaline is a non-selective beta adrenergic receptor agonist indicated to treat heart block, Adams-Stokes attacks, bronchospasm in anesthesia, cadiac arrest, hypovolemic shocks, septic shock, hypoperfusion
Synonyms: 1-(3,4-dihydroxyphenyl)-2-(isopropylamino)ethanol, 1-(3,4-dihydroxyphenyl)-2-isopropylaminoethanolCategories: Adrenergic beta-2 Receptor Agonists, Compounds used in a research, industrial, or household settingCarbidopa
go.drugbank.com/drugs/DB00190ApprovedInvestigationalIt potently inhibits aromatic amino acid decarboxylase (DDC) and due to its chemical properties, it does not cross the blood-brain barrier. … therapy developed by Mayne Pharma in 1992.
Synonyms: L-3-(3,4-dihydroxyphenyl)-2-methyl-2-hydrazinopropionic acidMixtures: LEVO/CA/EN 100/25/200 STD, LEV/CAR/EN AL200/50/200Tenapanor
go.drugbank.com/drugs/DB11761ApprovedInvestigational[L8558] It was first designed and synthesized in 2012. … [A185492] As an inhibitor of the sodium/hydrogen exchanger isoform 3 (NHE3) transporter, it is the first and currently only medication within its class[A185489,A185492,A185495] and therefore exists as
Categories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 SubstratesProducts: XPHOZAH 10 mg, XPHOZAH 20 mgEtilefrine
go.drugbank.com/drugs/DB08985ApprovedWithdrawnEtilefrine is an adrenergic agonist that appears to interact with beta-1 and some alpha-adrenergic receptors. It has been used as a vasoconstrictor agent.
International brands: Eti-PurenCategories: Compounds used in a research, industrial, or household setting