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Displaying results 1231 - 1240 of 6949 in total
  1. Drug

    Pepsin

    go.drugbank.com/drugs/DB13198
    ApprovedWithdrawn

    Interestingly, recent research has suggested that pepsin participates in the digestion of nucleic acids [L2391]. … Pepsin is often used as a replacement enzyme for those with pancreatic insufficiency [L2357].

  2. Drug

    Crotalus scutulatus antivenin

    go.drugbank.com/drugs/DB13891
    Approved

    Specimens with type A venom, which cause a different pattern of injury than other rattlesnakes, have been reported in southern California, Nevada, Utah, Arizona, Texas, and New Mexico [L2856]. … CroFab is more specifically tailored for crotalids of North America and is less allergenic than whole immunoglobulin antivenoms [L2861].

  3. Drug

    Ferrous gluconate

    go.drugbank.com/drugs/DB14488
    ApprovedInvestigational

    Mixtures: Supplement De Fer, Multi-force for Women Tab
  4. Drug

    Levonorgestrel

    go.drugbank.com/drugs/DB00367
    ApprovedInvestigational

    Levonorgestrel (LNG) is a synthetic progestogen similar to Progesterone used in contraception and hormone therapy. Also known as Plan B, it is used as a single agent in emergency contraception, and as a hormonal contraceptive released fr...

    Categories: Hormonal Contraceptives for Systemic Use
  5. Target

    Peroxisome proliferator-activated receptor alpha

    go.drugbank.com/bio_entities/BE0000071
    TargetHumans

    Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids.

    Polypeptides: Peroxisome proliferator-activated receptor alphaSynonyms: Nuclear receptor subfamily 1 group C member 1
  6. Target

    Glutamate receptor ionotropic, NMDA 1

    go.drugbank.com/bio_entities/BE0000365
    TargetHumans

    Component of N-methyl-D-aspartate (NMDA) receptors (NMDARs) that function as heterotetrameric, ligand-gated cation channels with high calcium permeability and voltage-dependent block by Mg(2+) (PubMed:21376300, PubMed:26875626, PubMed:26...

    Polypeptides: Glutamate receptor ionotropic, NMDA 1Synonyms: Glutamate [NMDA] receptor subunit zeta-1, N-methyl-D-aspartate receptor subunit NR1
  7. Target

    Glutamate receptor ionotropic, NMDA 2D

    go.drugbank.com/bio_entities/BE0000396
    TargetHumans

    Component of N-methyl-D-aspartate (NMDA) receptors (NMDARs) that function as heterotetrameric, ligand-gated cation channels with high calcium permeability and voltage-dependent block by Mg(2+) (PubMed:26875626, PubMed:27616483, PubMed:28...

    Polypeptides: Glutamate receptor ionotropic, NMDA 2DSynonyms: N-methyl D-aspartate receptor subtype 2D, Glutamate [NMDA] receptor subunit epsilon-4
  8. Target

    Glycine receptor subunit alpha-3

    go.drugbank.com/bio_entities/BE0000414
    TargetHumans

    Glycine receptors are ligand-gated chloride channels. Channel opening is triggered by extracellular glycine (PubMed:26416729, PubMed:9677400). Channel characteristics depend on the subunit composition; heteropentameric channels display f...

    Polypeptides: Glycine receptor subunit alpha-3
  9. Target

    Activin receptor type-1-like

    go.drugbank.com/bio_entities/BE0000459
    TargetHumans

    Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. … On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases.

    Polypeptides: Activin receptor type-1-likeSynonyms: Activin receptor-like kinase 1, TGF-B superfamily receptor type I
  10. Target

    Interleukin-1 receptor type 1

    go.drugbank.com/bio_entities/BE0000565
    TargetHumans

    Receptor for IL1A, IL1B and IL1RN (PubMed:2950091, PubMed:37315560). … Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits.

    Polypeptides: Interleukin-1 receptor type 1Synonyms: Interleukin-1 receptor alpha, Interleukin-1 receptor type I