Search
Tauroursodeoxycholic acid
go.drugbank.com/drugs/DB08834ApprovedInvestigationalWithdrawnTauroursodeoxycholic acid, also known as ursodoxicoltaurine, is a highly hydrophilic tertiary bile acid that is produced in humans at a low concentration. It is a taurine conjugate of ursodeoxycholic acid with comparable therapeutic effi...
Infigratinib
go.drugbank.com/drugs/DB11886ApprovedInvestigationalWithdrawnInfigratinib is a pan-fibroblast growth factor receptor (FGFR) kinase inhibitor. … [A198963] Infitratinib is a pan-FGFR inhibitor, as it is an ATP-competitive inhibitor of all four FGFR receptor subtypes.
Categories: Cytochrome P-450 Substrates, P-glycoprotein inhibitorsChlorpheniramine
go.drugbank.com/drugs/DB01114ApprovedInvestigationalA histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less dr...
Mixtures: Chlor-Tan A 12 Suspension, Pyrichlor PECategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 InhibitorsValine
go.drugbank.com/drugs/DB00161ApprovedInvestigationalNutraceuticalValine is a branched-chain essential amino acid that has stimulant activity. It promotes muscle growth and tissue repair. It is a precursor in the penicillin biosynthetic pathway.
Mixtures: Aminosyn-PF, Aminosyn-PFMiricorilant
go.drugbank.com/drugs/DB16234InvestigationalMiricorilant is under investigation in clinical trial NCT03818256 (Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Miricorilant (CORT118335) in Obese Adult Patients With Schizophrenia and Recent
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C19 SubstratesTransient receptor potential cation channel subfamily A member 1
go.drugbank.com/bio_entities/BE0001122TargetHumansAlso acts as an ionotropic cannabinoid receptor by being activated by delta(9)-tetrahydrocannabinol (THC), the psychoactive component of marijuana (PubMed:25389312).
Polypeptides: Transient receptor potential cation channel subfamily A member 1Synonyms: Wasabi receptorTransient receptor potential cation channel subfamily M member 8
go.drugbank.com/bio_entities/BE0001186TargetHumansNon-selective ion channel permeable to monovalent and divalent cations, including Na(+), K(+), and Ca(2+), with higher permeability for Ca(2+). Activated by multiple factors, such as temperature, voltage, pressure, and changes in osmolal...
Polypeptides: Transient receptor potential cation channel subfamily M member 8Synonyms: Transient receptor potential p8, Long transient receptor potential channel 6Low affinity immunoglobulin gamma Fc region receptor III-A
go.drugbank.com/bio_entities/BE0002097TargetHumansReceptor for the invariable Fc fragment of immunoglobulin gamma (IgG). … The ITAM-dependent signaling coupled to receptor phosphorylation by PKC mediates robust intracellular calcium flux that leads to production of pro-inflammatory cytokines, whereas in the absence of receptor
Polypeptides: Low affinity immunoglobulin gamma Fc region receptor III-ASynonyms: IgG Fc receptor III-2, IgG Fc receptor III-ALow affinity immunoglobulin gamma Fc region receptor II-c
go.drugbank.com/bio_entities/BE0002100TargetHumansReceptor for the Fc region of complexed immunoglobulins gamma. Low affinity receptor.
Polypeptides: Low affinity immunoglobulin gamma Fc region receptor II-cSynonyms: IgG Fc receptor II-cTransient receptor potential cation channel subfamily V member 3
go.drugbank.com/bio_entities/BE0003416TargetHumansNon-selective calcium permeant cation channel (PubMed:12077604, PubMed:12077606, PubMed:26818531, PubMed:37648856, PubMed:38691614). It is activated by innocuous (warm) temperatures and shows an increased response at noxious temperatures...
Polypeptides: Transient receptor potential cation channel subfamily V member 3Synonyms: Vanilloid receptor-like 3