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Displaying results 1231 - 1240 of 10000 in total
  1. Target

    Neutral amino acid transporter A

    go.drugbank.com/bio_entities/BE0000480
    TargetHumans

    Involved in homeostasis of D-serine, a coagonist of synaptic NMDA receptors. … In a tri-substrate transport cycle, exchanges neutral amino acids between the extracellular and intracellular compartments, coupled to the inward cotransport of at least one sodium ion (PubMed:24808181

    Polypeptides: Neutral amino acid transporter A
  2. Target

    U1 small nuclear ribonucleoprotein A

    go.drugbank.com/bio_entities/BE0002708
    TargetHumans

    In a snRNP-free form (SF-A) may be involved in coupled pre-mRNA splicing and polyadenylation process. May bind preferentially to the 5'-UGCAC-3' motif on RNAs

    Polypeptides: U1 small nuclear ribonucleoprotein ASynonyms: U1-A, U1 snRNP A
  3. Target

    DNA topoisomerase 4 subunit A

    go.drugbank.com/bio_entities/BE0003726
    TargetStreptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)

    Performs the decatenation events required during the replication of a circular DNA molecule.

    Polypeptides: DNA topoisomerase 4 subunit ASynonyms: Topoisomerase IV subunit A
  4. Target

    Myocardin-related transcription factor A

    go.drugbank.com/bio_entities/BE0004156
    TargetHumans

    Activity is also regulated by filamentous actin (F-actin) in the nucleus … The SRF-MRTFA complex activity responds to Rho GTPase-induced changes in cellular globular actin (G-actin) concentration, thereby coupling cytoskeletal gene expression to cytoskeletal dynamics.

    Polypeptides: Myocardin-related transcription factor ASynonyms: MRTF-A
  5. Target

    Ephrin type-A receptor 5

    go.drugbank.com/bio_entities/BE0005587
    TargetHumans

    Together with EFNA5 plays also a role in synaptic plasticity in adult brain through regulation of synaptogenesis. … Among GPI-anchored ephrin-A ligands, EFNA5 most probably constitutes the cognate/functional ligand for EPHA5.

    Polypeptides: Ephrin type-A receptor 5
  6. Target

    Ephrin type-A receptor 4

    go.drugbank.com/bio_entities/BE0009438
    TargetHumans

    In addition to its role in axonal guidance plays a role in synaptic plasticity. … In the nervous system, also plays a role in repair after injury preventing axonal regeneration and in angiogenesis playing a role in central nervous system vascular formation.

    Polypeptides: Ephrin type-A receptor 4
  7. Target

    Acyl-coenzyme A thioesterase 1

    go.drugbank.com/bio_entities/BE0016368
    EnzymeHumans

    Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels.

    Polypeptides: Acyl-coenzyme A thioesterase 1Synonyms: Palmitoyl-coenzyme A thioesterase, Inducible cytosolic acyl-coenzyme A thioester hydrolase
  8. Drug

    Mineral oil

    go.drugbank.com/drugs/DB11057
    ApprovedInvestigationalVet approved

    It is also used as a mild laxative for human or veterinary uses. … Mineral oil, or paraffin oil, is a mixture of higher alkanes from a mineral source, such as petroleum.

    Mixtures: I-defense, AGAROL CON SABOR A FRAMBUESAProducts: Gelee Laxative A LA Framboise, Clean It Zero Radiance
  9. Drug

    Vinblastine

    go.drugbank.com/drugs/DB00570
    ApprovedInvestigational

    Antitumor alkaloid isolated from Vinca rosea. (Merck, 11th ed.)

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, BSEP/ABCB11 Substrates with a Narrow Therapeutic IndexProducts: VINKO 1 MG/ML IV INFÜZYON ICIN COZELTİ ICEREN FLAKON, 1 ADET, VELBASTINE INJ 10MG
  10. Drug

    Bupivacaine

    go.drugbank.com/drugs/DB00297
    ApprovedInvestigational

    Bupivacaine is a widely used local anesthetic agent.

    Mixtures: Mlp A-2, Mlp A-1Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates