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Probenecid
go.drugbank.com/drugs/DB01032ApprovedInvestigationalIt inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. … Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
Categories: combinations of sulfonamides, Preparations With No Effect on Uric Acid MetabolismProducts: PROBENECID TABLET 500 mgTetracaine
go.drugbank.com/drugs/DB09085ApprovedInvestigationalVet approvedTetracaine is an ester local anaesthetic currently available in combination with lidocaine as a cream and patch.
Mixtures: Pliaglis 70 mg/g + 70 mg/g Creme, Pliaglis 70 mg/g + 70 mg/g creamCategories: Esters of Aminobenzoic Acid, Agents for Treatment of Hemorrhoids and Anal Fissures for Topical UseMacitentan
go.drugbank.com/drugs/DB08932ApprovedInvestigationalMacitentan differs from its predecessor [bosentan] in part due to its lower risk of hepatotoxicity. … Macitentan is a dual endothelin receptor antagonist used in the treatment of pulmonary arterial hypertension (PAH).[L35890] It was first approved by the FDA in 2013.
Mixtures: OPSYNVI® (MACITENTAN/TADALAFILO) 10MG/40 MG TABLETAS RECUBIERTASProducts: MACITENT® 10 MG, MACITENTAN 10 MGPerflutren
go.drugbank.com/drugs/DB00556ApprovedInvestigationalDuring echocardiography, activated Perflutren enhances images of the inner edges or borders of the heart, producing an improved image that may enable physicians to better diagnose patients. … The difference in density between the gas-filled bubbles and the blood around them creates an increased level of contrast visible in the resulting ultrasound image.
Categories: Diagnostic Uses of Chemicals, Compounds used in a research, industrial, or household settingProducts: CIPROFLOXACINO TABLETAS X 500 MGDomperidone
go.drugbank.com/drugs/DB01184ApprovedInvestigationalVet approvedA specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
Mixtures: DEXGARD 30/30 MG MR KAPSUL, 60 ADET, LACOMBI 15/10 MG KAPSUL, 28 ADETProducts: Nu-domperidone 10 Mg Tablets, DOMPERIDONE FGPiperonyl butoxide
go.drugbank.com/drugs/DB09350ApprovedVet approvedIt has no pesticidal activity of its own, but acts to increase the activity of pesticides such as carbamates, pyrethrins, pyrethroids, and rotenone. … Piperonyl butoxide is a semisynthetic derivative of safrole.
Mixtures: Dg Health Lice Killing Maximum StrengthCategories: Compounds used in a research, industrial, or household settingIptacopan
go.drugbank.com/drugs/DB16200ApprovedInvestigational[A262581] This is of particular importance to PNH, where one of the disease hallmarks is the mutation of the PIGA gene. … [A262581] On December 6th, 2023, Iptacopan under the brand name Fabhalta was approved by the FDA for the treatment of adults with PNH.
Categories: Diagnostic Uses of Chemicals, Compounds used in a research, industrial, or household settingAprepitant
go.drugbank.com/drugs/DB00673ApprovedInvestigationalAprepitant has little or no affinity for serotonin (5-HT3), dopamine, and corticosteroid receptors, the targets of existing therapies for chemotherapy-induced nausea and vomiting (CI NV). … associated with initial and repeat courses of highly emetogenic cancer chemotherapy.
Mixtures: EMEND® 80 MG/125 MG, EMEND® 80 MG/125 MGProducts: Atanto 125 mg/80 mg Hartkapseln, Aprepitant ratiopharm 80 mg/125 mg HartkapselnPyrantel
go.drugbank.com/drugs/DB11156ApprovedVet approvedPyrantel is on the World Health Organization's List of Essential Medicines, which are the safest and most effective medicines required in a functioning health system [L1901], [L1902]. … A depolarizing neuromuscular-blocking agent causing longstanding nicotinic receptor activation, resulting in spastic paralysis of susceptible nematodes (worms).
Mixtures: PAMOATO DE OXANTEL 250 MG/5ML + PAMOATO DE PIRANTEL 250 MG/5 ML SUSPENSIÓN., PAMOXPEN - PAMOATO DE PIRANTEL100 MG+ PAMOATO DE OXANTEL 100 MG TABLETASProducts: NEMIOTINA 250 MG, BEARANTEL TABLETS 125 mgArtemether
go.drugbank.com/drugs/DB06697ApprovedInvestigationalThis combination therapy exerts its effects against the erythrocytic stages of <i>Plasmodium spp.
Mixtures: Riamet 20 mg/120 mg - Tabletten, ARTEMETERO 20 MG + LUMEFANTRINA 120 MG TABLETA