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Mercaptopurine
go.drugbank.com/drugs/DB01033ApprovedInvestigationalIt interferes with nucleic acid synthesis by inhibiting purine metabolism and is used, usually in combination with other drugs, in the treatment of or in remission maintenance programs for leukemia. … An antimetabolite antineoplastic agent with immunosuppressant properties.
Categories: Drugs for Obstructive Airway Diseases, OAT3/SLC22A8 Substrates with a Narrow Therapeutic IndexSerplulimab
go.drugbank.com/drugs/DB17451ApprovedInvestigationalIt was first approved in China - where it is indicated for a number of different cancers[L52963] - and has since been approved in several southeast Asian countries. … Most recently, it was approved in the EU in February 2025 for the treatment of extensive-stage small cell lung cancer.[L52968,L52953]
Categories: PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitorsCasimersen
go.drugbank.com/drugs/DB14984ApprovedInvestigational[A218186] Casimersen is the most recent in a line of approved PMOs for treating DMD, including [eteplirsen] and [viltolarsen]. … [A218171, A218176, A229988] The application of antisense oligonucleotides in DMD patients with specific mutations allows for exon skipping to produce truncated BMD-like dystrophin proteins, which restore
Categories: Compounds used in a research, industrial, or household settingSodium carbonate
go.drugbank.com/drugs/DB09460ApprovedWithdrawnWhen dissolved in water, sodium carbonate forms carbonic acid and sodium hydroxide. As a strong base, sodium hydroxide neutralizes gastric acid thereby acting as an antacid.
Mixtures: GAVISCON® TABLETAS MASTICABLES SABOR A MENTA, Urologic G for IrrigationAdenosine phosphate
go.drugbank.com/drugs/DB00131ApprovedInvestigationalNutraceuticalWithdrawnAdenosine phosphate was withdrawn by the FDA since it was considered neither safe nor effective for its intended uses as a vasodilator and an anti-inflammatory.[L43937] … Adenosine phosphate, or adenylic acid, is an adenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position.
International brands: My-B-DenPiperidione
go.drugbank.com/drugs/DB13224ExperimentalPiperidione was cough medicine marketed by Roche under the trade name Sedulon.
Maribavir
go.drugbank.com/drugs/DB06234ApprovedInvestigationalMaribavir was approved by the FDA in November 2021, under the name Livtencity (Takeda), for the treatment of resistant CMV infections in post-transplant patients. … [L39322] Most standard CMV therapies, such as [ganciclovir] or [foscarnet], target CMV DNA polymerase - while generally effective, these medications tend to promote the development of CMV resistance to
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseButalbital
go.drugbank.com/drugs/DB00241ApprovedIllicitButalbital, or 5-allyl-5-isobutylbarbituric acid, is a derivative of barbituric acid which the hydrogens at position 5 are substituted by an allyl group and an isobutyl group. … [L10370] Butalbital‐containing analgesics can also produce a drug‐induced headache in addition to tolerance and dependence.
Mixtures: Vtol LQ, Alagesic LQSynonyms: 5-allyl-5-(2'-methyl-n-propyl) barbituric acidCetrorelix
go.drugbank.com/drugs/DB00050ApprovedInvestigationalWhen undergoing hormone treatment sometimes premature ovulation can occur, leading to eggs that are not ready for fertilization to be released. … GnRH controls another hormone that is called luteinizing hormone (LH), which is the hormone that starts ovulation during the menstrual cycle.
Products: Cetrotide 0.25 mg powder and solvent for solution for injection, Asporelix 0.25 (Cetrorelix 0.25mg Powder and Solvent for Solution for Injection)Maraviroc
go.drugbank.com/drugs/DB04835ApprovedInvestigationalIt was approved for use by the FDA in August, 2007. … Maraviroc (brand-named Selzentry, or Celsentri outside the U.S.) is a chemokine receptor antagonist drug developed by the drug company Pfizer that is designed to act against HIV by interfering with the
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic Use